UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. ヌクレオシド系逆転写酵素阻害剤の薬理学 pharmacology of nucleoside reverse transcriptase inhibitors
- 2. HIV抗レトロウイルス療法に関する臨床試験：ヌクレオシド系逆転写酵素阻害剤を使用した3剤療法 clinical trials of hiv antiretroviral therapy triple regimens using nucleoside reverse transcriptase inhibitors
- 3. HIVヌクレオシド系逆転写酵素阻害剤のミトコンドリア毒性 mitochondrial toxicity of hiv nucleoside reverse transcriptase inhibitors
- 4. 未治療HIV感染患者のための選択的抗レトロウイルス療法 selecting antiretroviral regimens for the treatment naive hiv infected patient
- 5. 非ヌクレオシド系逆転写酵素阻害剤の薬理学 pharmacology of non nucleoside reverse transcriptase inhibitors
English Journal
- HIV-1 RNA and HIV-1 DNA persistence during suppressive ART with PI-based or nevirapine-based regimens.
- Kiselinova M1, Geretti AM2, Malatinkova E1, Vervisch K1, Beloukas A2, Messiaen P3, Bonczkowski P1, Trypsteen W1, Callens S4, Verhofstede C5, De Spiegelaere W1, Vandekerckhove L6.
- The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2015 Dec;70(12):3311-6. doi: 10.1093/jac/dkv250. Epub 2015 Aug 31.
- OBJECTIVES: Whether ART regimens differ in their propensity to allow persistent HIV-1 detection remains unclear. To investigate this, we performed a cross-sectional study to characterize HIV-1 persistence in peripheral blood during suppressive therapy with NRTIs plus a PI or nevirapine.METHODS: Resi
- PMID 26324076
- HIV Salvage Therapy Does Not Require Nucleoside Reverse Transcriptase Inhibitors: A Randomized, Controlled Trial.
- Tashima KT, Smeaton LM, Fichtenbaum CJ, Andrade A, Eron JJ, Gandhi RT, Johnson VA, Klingman KL, Ritz J, Hodder S, Santana JL, Wilkin T, Haubrich RH; A5241 Study Team.
- Annals of internal medicine.Ann Intern Med.2015 Nov 24:908-917. doi: 10.7326/M15-0949. [Epub ahead of print]
- Background: Nucleoside reverse transcriptase inhibitors (NRTIs) are often included in antiretroviral regimens in treatment-experienced patients in the absence of data from randomized trials.Objective: To compare treatment success between participants who omit versus those who add NRTIs to an optimiz
- PMID 26595748
- Neurocognitive function at first-line failure and on second-line antiretroviral therapy in Africa: Analyses from the EARNEST Trial.
- Kambugu A1, Thompson J, Hakim J, Tumukunde D, van Oosterhout JJ, Mwebaze R, Hoppe A, Abach J, Kwobah C, Arenas-Pinto A, Walker AS, Paton NI.
- Journal of acquired immune deficiency syndromes (1999).J Acquir Immune Defic Syndr.2015 Nov 16. [Epub ahead of print]
- OBJECTIVE: To assess neurocognitive function at first-line antiretroviral therapy failure and change on second-line therapy DESIGN:: Randomized controlled trial conducted in 5 sub-Saharan African countries.METHODS: Patients failing first-line therapy according to WHO criteria after >12 months on
- PMID 26579985
Japanese Journal
- Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia
- Tada K.,Kobayashi M.,Takiuchi Y.,Iwai F.,Sakamoto T.,Nagata K.,Shinohara M.,Io K.,Shirakawa K.,Hishizawa M.,Shindo K.,Kadowaki N.,Hirota K.,Yamamoto J.,Iwai S.,Sasanuma H.,Takeda S.,Takaori-Kondo A.
- Science Advances 1(3), 2015-04-24
- … We analyzed the cytotoxic effects of various nucleoside analog reverse transcriptase inhibitors (NRTIs) for HIV-1 on ATL cells and found that abacavir potently and selectively kills ATL cells. … Although NRTIs have minimal genotoxicities on host cells, the therapeutic concentration of abacavir induced numerous DNA double-strand breaks (DSBs) in the chromosomal DNA of ATL cells. …
- NAID 120005601014
- 抗HIV治療薬
- 鯉渕 智彦
- ウイルス 63(2), 199-208, 2013
- 抗HIV治療薬は，逆転写酵素阻害薬，プロテアーゼ阻害薬（PI: protease inhibitor），インテグラーゼ阻害薬（INSTI: integrase strand transfer inhibitor），侵入阻害薬（CCR5阻害薬）に大別され，さらに逆転写酵素阻害薬はヌクレオシド系（NRTI: nucleoside/nucleotide reverse transcriptase in …
- NAID 130004713425
- Vitamin A and Beta-Carotene Concentrations in Adults with HIV/AIDS on Highly Active Antiretroviral Therapy
- KAIO Daniella Junko,RONDÓ Patricia Helen Carvalho,SOUZA José Maria Pacheco,FIRMINO Aline Vale,LUZIA Liania Alves,SEGURADO Aluisio Augusto
- Journal of Nutritional Science and Vitaminology 59(6), 496-502, 2013
- … Patients were divided into 3 groups according to their HAART regimen: combination of nucleoside analog reverse transcriptase inhibitors (NRTIs) and non-NRTIs; … combination of NRTIs, protease inhibitors, and ritonavir; … combination of NRTIs and other classes. …
- NAID 130003393745
Related Links
- 概要 ①何について何をする技術なのか? ・核磁気共鳴による赤錆防止・配管延命工法 ②従来はどのような技術で対応していたのか? ・エポキシライニング工法 ③公共工事のどこに適用できるのか? ・給水・空調冷温水・冷却水配管等の ...
- NETIS(新技術情報提供システム)についてご説明します。NETIS登録商品を活用することで工事成績アップにつながります。 ... NETISとは 新技術情報提供システム(New Technology Information System) 。 国土交通省が有用な新技術の ...
Related Pictures
★リンクテーブル★
| 拡張検索 | 「NNRTIs」 |
| 関連記事 | 「NRTI」「NRT」 |
「NNRTIs」
- 関
- Non-nucleoside reverse transcriptase inhibitors