- 関
- Non-nucleoside reverse transcriptase inhibitors
- 同
- non-nucleoside reverse transcriptase inhibibors
UpToDate Contents
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English Journal
- Increase in transmitted HIV drug resistance among persons undergoing genotypic resistance testing in Ontario, Canada, 2002-09.
- Burchell AN, Bayoumi AM, Rourke SB, Major C, Gardner S, Sandstrom P, Rachlis A, Taylor D, Mazzulli T, Fisher M, Brooks J; on behalf of the OHTN Cohort Study Research Team.SourceOntario HIV Treatment Network, Toronto, Canada.
- The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2012 Nov;67(11):2755-2765. Epub 2012 Jul 24.
- OBJECTIVES: To characterize persons undergoing HIV genotypic resistance testing (GRT) while treatment naive and to estimate the prevalence of transmitted HIV drug resistance (TDR) among HIV-positive outpatients in Ontario, Canada.METHODS: We analysed data from a multi-site cohort of persons receivin
- PMID 22833637
- Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine.
- Frasco MA, Mack WJ, Van Den Berg D, Aouizerat BE, Anastos K, Cohen M, De Hovitz J, Golub ET, Greenblatt RM, Liu C, Conti DV, Pearce CL.SourceaDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles bSchool of Nursing cInstitute for Human Genetics, University of California, San Francisco, California dDepartment of Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York eDepartment of Medicine, Stroger Hospital and Rush University, Chicago, Illinois fDepartment of Preventive Medicine and Community Health, SUNY Health Sciences Center, Brooklyn, New York gDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland hDepartment of Clinical Pharmacy, Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California iDepartment of Medicine, Georgetown University School of Medicine, Washington, District of Columbia, USA.
- AIDS (London, England).AIDS.2012 Oct 23;26(16):2097-2106.
- OBJECTIVE:: CYP2B6 variation predicts pharmacokinetic characteristics of its substrates. Consideration for underlying genetic structure is critical to protect against spurious associations with the highly polymorphic CYP2B6 gene. DESIGN:: The effect of CYP2B6 variation on response to its substrates,
- PMID 22951632
Japanese Journal
- Efficacy and safety of antiretroviral regimens including raltegravir to treat HIV-infected patients with hemophilia
- Mass Spectrometric Characterization of HIV-1 Reverse Transcriptase Interactions with Non-nucleoside Reverse Transcriptase Inhibitors
- Efficacy and safety of antiretroviral regimens including raltegravir to treat HIV-infected patients with hemophilia
Related Links
- In contrast, NNRTIs have a completely different mode of action. NNRTIs block reverse transcriptase by binding at a different site on the enzyme, compared to NRTIs and NtRTIs. NNRTIs are not incorporated into the viral DNA but instead inhibit ...
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非ヌクレオシド系逆転写酵素阻害薬 nonnucleoside reverse transcriptase inhibitor