関: leucine enkephalin

WordNet

the 12th letter of the Roman alphabet (同)l
the basic unit of money in Moldova
the basic unit of money in Romania
an endorphin having opiate qualities that occurs in the brain and spinal cord and elsewhere

PrepTutorEJDIC

lira(イタリアの貨幣単位リラ)
レウ(ルーマニアの貨幣単位)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/03/05 19:38:56」(JST)

wiki en

Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine. Leu-enkephalin has agonistic actions at both the μ- and δ-opioid receptors, with significantly greater preference for the latter. It has little to no effect on the κ-opioid receptor.

References

This biochemistry article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. ACTH、CRH、および他の視床下部／下垂体ペプチドの測定 measurement of acth crh and other hypothalamic and pituitary peptides
2. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
3. コルチコトロピン-放出ホルモン（CRH）の生理学 physiology of corticotropin releasing hormone
4. ゴケグモによる咬刺傷の臨床症状および診断 clinical manifestations and diagnosis of widow spider bites
5. 病的賭博の概要 overview of gambling disorder

English Journal

Nylon nanoweb with TiO2 nanoparticles as a solid matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Kim JI1, Ryu SY, Park JM, Noh JY, Kang MJ, Kwak SY, Pyun JC.
Rapid communications in mass spectrometry : RCM.Rapid Commun Mass Spectrom.2014 Nov 30;28(22):2427-36. doi: 10.1002/rcm.7036.
RATIONALE: The solid matrices used for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) enable the analysis of small molecules by preventing fragmentations of organic matrix molecules in the low mass-to-charge ratio (m/z) range. In this work, a nylon nanoweb
PMID 25303471

Simple Setup for Gas-Phase H/D Exchange Mass Spectrometry Coupled to Electron Transfer Dissociation and Ion Mobility for Analysis of Polypeptide Structure on a Liquid Chromatographic Time Scale.

Mistarz UH1, Brown JM, Haselmann KF, Rand KD.
Analytical chemistry.Anal Chem.2014 Nov 20. [Epub ahead of print]
Gas-phase hydrogen/deuterium exchange (HDX) is a fast and sensitive, yet unharnessed analytical approach for providing information on the structural properties of biomolecules, in a complementary manner to mass analysis. Here, we describe a simple setup for ND3-mediated millisecond gas-phase HDX ins
PMID 25375223

The human cuneate nucleus contains discrete subregions whose neurochemical features match those of the relay nuclei for nociceptive information.

Del Fiacco M1, Quartu M, Serra MP, Boi M, Demontis R, Poddighe L, Picci C, Melis T.
Brain structure & function.Brain Struct Funct.2014 Nov;219(6):2083-101. doi: 10.1007/s00429-013-0625-4. Epub 2013 Aug 23.
The present paper is aimed at defining distinctive subdivisions of the human cuneate nucleus (Cu), evident from prenatal to old life, whose occurrence has never been clearly formalized in the human brain, or described in other species so far. It extends our early observations on the presence of gray
PMID 23975345

Japanese Journal

高次元アルゴリズム (HA : Hamiltonian Algorithm) を用いた Enkephalin の立体構造の分子動力学的研究 : HAに現れる mixing 係数の効果

土屋恭平,寺前裕之,渡邊寿雄 [他],石元孝佳,長嶋雲兵
Journal of computer chemistry, Japan 6(5), 275-282, 2007-12-15
… Leu-EnkephalinとMet-Enkephalinの二種類のタンパク質を計算対象とした。 …
NAID 130000056887

ジアジリン型光反応性リガンドによるオピオイド結合細胞接着分子(OBCAM)の光アフィニティーラベリング

定金豊,北本英二郎,友廣岳則 [他],木葉敬子,川原正博,畑中保丸
九州保健福祉大学研究紀要 8, 179-185, 2007-03-25
… しかしながら、[Leu]-エンケファリン,[D-Ala^2, D-Leu^5]-エンケファリンおよびβ-エンドルフィンを過剰に加えても、この複合体形成を阻害できなかった。 …
NAID 110006407510

高次元アルゴリズム(HA: Hamiltonian Algorithm)を用いたEnkephalinの立体構造の分子動力学的研究 : HAに現れるmixing 係数の効果

土屋恭平,寺前裕之,渡邊寿雄,石元孝佳,長嶋雲兵
Journal of Computer Chemistry, Japan 6(5), 275-282, 2007
… Leu-Enkephalin とMet-Enkephalin の二種類のタンパク質を計算対象とした。 …
NAID 120005520445

Related Pictures

★リンクテーブル★

リンク元	「leucine enkephalin」
関連記事	「L」

「leucine enkephalin」

Leu-enkephalin
	IUPAC name (2R)-2-[[(2R)-2-[[2-[[2-[[(2R)-2-amino-3-; (4-hydroxyphenyl)propanoyl]amino]acetyl]; amino]acetyl]amino]-3-phenylpropanoyl]; amino]-4-methylpentanoic acid
Identifiers
CAS number	58822-25-6
PubChem	10415290
ChemSpider	21106451
ChEMBL	CHEMBL8234
IUPHAR ligand	1613
Jmol-3D images	Image 1
	SMILES Oc2ccc(C[C@H](N)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(O)=O)cc2 ;
	InChI InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22+,23-/m0/s1 ; Key: URLZCHNOLZSCCA-ZRBLBEILSA-N InChI=1/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22+,23-/m0/s1; Key: URLZCHNOLZSCCA-ZRBLBEILBT ;
Properties
Molecular formula	C28H37N5O7
Molar mass	555.62268 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references