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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/27 02:46:02」(JST)
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English Journal
- EpCAM expression in the prostate cancer makes the difference in the response to growth factors.
- Yoshida GJ, Saya H.SourceDivision of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address: medical21go@yahoo.co.jp.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2013 Dec 2. pii: S0006-291X(13)01995-5. doi: 10.1016/j.bbrc.2013.11.093. [Epub ahead of print]
- INTRODUCTION: Epithelial cell adhesion molecule (EpCAM) is expressed in tumors with an epithelial cell of origin, in a heterogeneous manner. Prostate cancer stem-like cells highly express EpCAM. However, little is known about how EpCAM is involved in the ability of cells to adapt to micro-environmen
- PMID 24309103
- L-methionine placental uptake: characterization and modulation in gestational diabetes mellitus.
- Araújo JR, Correia-Branco A, Ramalho C, Gonçalves P, Pinho MJ, Keating E, Martel F.Source1Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Porto, Portugal.
- Reproductive sciences (Thousand Oaks, Calif.).Reprod Sci.2013 Dec;20(12):1492-507. doi: 10.1177/1933719113488442. Epub 2013 May 7.
- Our aim was to investigate the influence of gestational diabetes mellitus (GDM) and GDM-associated conditions upon the placental uptake of (14)C-l-methionine ((14)C-l-Met). The (14)C-l-Met uptake by human trophoblasts (TBs) obtained from normal pregnancies (normal trophoblast [NTB] cells) is mainly
- PMID 23653387
- Protein Synthesis in Skeletal Muscle of Neonates Is Enhanced by Administration of β-Hydroxy-β-Methylbutyrate.
- Wheatley SM, El-Kadi SW, Suryawan A, Boutry C, Orellana RA, Nguyen HV, Davis SR, Davis TA.Source1Baylor College of Medicine.
- American journal of physiology. Endocrinology and metabolism.Am J Physiol Endocrinol Metab.2013 Nov 5. [Epub ahead of print]
- Many low birth weight infants experience failure to thrive. The amino acid, leucine, stimulates protein synthesis in skeletal muscle of the neonate but less is known about the effects of the leucine metabolite, β-hydroxy-β-methylbutyrate (HMB). To determine the effects of HMB on protein synthesis
- PMID 24192287
Japanese Journal
- LAT1 Is a Central Transporter of Essential Amino Acids in Human Umbilical Vein Endothelial Cells
- Hayashi Keitaro,Jutabha Promsuk,Kamai Takao [他]
- Journal of pharmacological sciences 124(4), 511-513, 2014-04
- NAID 40020051393
- LAT1 Is a Central Transporter of Essential Amino Acids in Human Umbilical Vein Endothelial Cells
- Hayashi Keitaro,Jutabha Promsuk,Kamai Takao,Endou Hitoshi,Anzai Naohiko
- Journal of Pharmacological Sciences, 2014
- … Here we show that L-type amino acid transporter 1 (LAT1) is a major transporter of essential amino acids in human umbilical vein endothelial cells (HUVECs). … Growing HUVECs express a certain level of LAT1. … A LAT1-specific inhibitor suppressed leucine uptake, cell proliferation, and tube formation of HUVECs. … Therefore, LAT1 acts to support effective uptake of amino acids, which is critical for the optimal function of HUVECs for angiogenesis. …
- NAID 130003391512
- 癌細胞におけるc-MycによるLAT1の発現制御
- 林 啓太朗,安西 尚彦
- Dokkyo journal of medical sciences 40(2), 137, 2013-07-25
- NAID 110009673625
Related Links
- トランスポーターは生体を正常に機能させるために重要ですが、例えばLAT1（L-type amino acid transporter 1; SLC7A5）と名付けられた多くの必須アミノ酸を輸送する トランスポーターは、がん（腫瘍）細胞で特にその発現が増加していることが分かりました （ ...
- での高発現を見出して単離した必須アミノ酸トランスポーター（LAT1）であり、開発する抗 がん薬は. LAT1 機能を選択的に阻害する ... がん患者選別には、内視鏡下に採取され るがん生検組織中の LAT １の発現強度を抗 LAT1 抗体により. 確立したがんの悪性度 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「large neutral amino acid-transporter 1」「大型中性アミノ酸輸送体1」 |
| 関連記事 | 「LA」 |