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1. 皮膚リーシュマニア症：臨床症状と診断 cutaneous leishmaniasis clinical manifestations and diagnosis
2. 皮膚リーシュマニア症：治療 cutaneous leishmaniasis treatment

An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis.

Costa Duarte M1, Dos Reis Lage LM1, Lage DP2, Mesquita JT3, Salles BC2, Lavorato SN4, Menezes-Souza D1, Roatt BM1, Alves RJ5, Tavares CA6, Tempone AG3, Coelho EA7.
Veterinary parasitology.Vet Parasitol.2016 Feb 15;217:81-8. doi: 10.1016/j.vetpar.2016.01.002. Epub 2016 Jan 7.
The development of new therapeutic strategies to treat leishmaniasis has become a priority. In the present study, the antileishmanial activity of 8-hydroxyquinoline (8-HQN) was investigated against in vitro promastigotes and in vivo intra-macrophage amastigotes of three Leishmania species: Leishmani
PMID 26827866

Clinical and epidemiological features of leishmaniasis in northwestern-Argentina through a retrospective analysis of recent cases.

García Bustos MF1, González-Prieto G2, Ramos F2, Mora MC2, Hashiguchi Y3, Parodi C4, Basombrío MA4, Moreno S5, Monroig S6, Beckar J6, Jaime D7, Sajama J8, Yeo M9, Marco JD4, Locatelli FM10, Barrio A11.
Acta tropica.Acta Trop.2016 Feb;154:125-32. doi: 10.1016/j.actatropica.2015.11.008. Epub 2015 Nov 21.
Leishmaniasis is a parasitic disease caused by hemoflagellates of the genus Leishmania and is transmitted to humans by the bite of infected phlebotomine sandflies. Depending on the Leishmania species, the disease has different clinical forms including cutaneous, mucocutaneous, and visceral manifesta
PMID 26611809

Prenylated Acylphloroglucinols with Leishmanicidal Activity from the Fern Elaphoglossum lindbergii.

Socolsky C1, Salamanca E2, Giménez A2, Borkosky SA3, Bardón A1.
Journal of natural products.J Nat Prod.2016 Jan 22;79(1):98-105. doi: 10.1021/acs.jnatprod.5b00767. Epub 2015 Dec 21.
Purification of a diethyl ether extract of the Argentinian fern Elaphoglossum lindbergii afforded five new prenylated acylphloroglucinols, lindbergins E-I (1-5), of which two showed significant in vitro leishmanicidal activity against promastigotes of Leishmania braziliensis and L. amazonensis. The
PMID 26689830

Regulation of Cytochrome c- and Quinol Oxidases, and Piezotolerance of Their Activities in the Deep-Sea Piezophile Shewanella violacea DSS12 in Response to Growth Conditions

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Bioscience, Biotechnology, and Biochemistry 77(7), 1522-1528, 2013
… Even in the membranes of the non-piezophile Shewanella amazonensis, quinol oxidase was more piezotolerant than cytochrome c oxidase, although both were highly piezosensitive as compared to the activities in DSS12. …
NAID 130003361160

Ba1-1 Shewanella amazonensis由来GH99エンド-α-マンノシダーゼの基質特異性の解析(糖質関連酵素(α-グルコシダーゼ,マンノシダーゼ,フルクトシダーゼ他),一般講演,日本応用糖質科学会平成24年度大会(第61回))

Synthesis, Antitumor, Antitrypanosomal and Antileishmanial Activities of Benzo[4,5]canthin-6-ones Bearing the N′-(Substituted benzylidene)-carbohydrazide and N-Alkylcarboxamide Groups at C-2

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Chemical and Pharmaceutical Bulletin 60(11), 1372-1379, 2012
… A series of novel benzo[4,5]canthin-6-ones, bearing the N′-(substituted benzylidene)-carbohydrazide (11a–e) and N-alkylcarboxamide (13a–g) moieties at position-2, were synthesized and screened for their in vitro antitumor activity, against seven human cancer cell lines, and for antitrypanosomal and antileishmanial activities against Trypanosoma cruzi and Leishmania amazonensis. …
NAID 130001852377