English Journal

Disease burden of the most commonly detected respiratory viruses in hospitalized patients calculated using the disability adjusted life year (DALY) model.

Gaunt ER, Harvala H, McIntyre C, Templeton KE, Simmonds P.SourceDepartment of Medicine, University of Cambridge, Level 5, Box 157, Addenbrooke's hospital, Cambridge CB2 0QQ, UK.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.J Clin Virol.2011 Nov;52(3):215-21. Epub 2011 Aug 30.
BACKGROUND: The most common acute infections occur in the respiratory tract. Recent discoveries of several novel viruses have markedly increased the repertoire of agents understood to cause presentations of acute respiratory disease.OBJECTIVES: Further understanding is needed of the relative importa
PMID 21880543

1H, 13C, and 15N resonance assignment of the central domain of hRSV transcription antitermination factor M2-1.

Dubosclard V, Blondot ML, Eleouet JF, Bontems F, Sizun C.SourceUnite de Virologie et Immunologie Moleculaires, INRA UR0892, 78350, Jouy-en-Josas, France.
Biomolecular NMR assignments.Biomol NMR Assign.2011 Oct;5(2):237-9. Epub 2011 Apr 27.
M2-1 is an essential co-factor of the respiratory syncytial virus, an important respiratory pathogen in infants and calves. It acts as a transcription antitermination factor which enhances the processivity of the polymerase. Within the polymerase complex, M2-1 interacts with a second co-factor, the
PMID 21523439