WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

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1. 適応細胞性免疫応答 the adaptive cellular immune response
2. アポトーシスと自己免疫疾患 apoptosis and autoimmune disease
3. 大顆粒T細胞リンパ球性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of t cell large granular lymphocyte leukemia
4. 母体 - 胎児接点の免疫 immunology of the maternal fetal interface
5. 原発性免疫不全症の診断のためのフローサイトメトリー flow cytometry for the diagnosis of primary immunodeficiencies

Wu SS, Chen LG, Lin RJ, Lin SY, Lo YE, Liang YC.SourceDepartment of Orthopedics, Shuang Ho Hospital, Taipei Medical University , Taipei , Taiwan.
Drug and chemical toxicology.Drug Chem Toxicol.2013 Jul;36(3):313-9. doi: 10.3109/01480545.2012.720990. Epub 2012 Oct 3.
Vitis thunbergii var. taiwaniana (VTT) is an indigenous Taiwanese wild grape and is used as a folk medicine in Taiwan. VTT is rich in polyphenols, especially quercetin and resveratrol derivatives, which were demonstrated to exhibit inhibitory activities against carcinogenesis and prevent some neurod
PMID 23030068

Rapold RA, Wueest S, Knoepfel A, Schoenle EJ, Konrad D.SourceDivision of Pediatric Endocrinology and Diabetology and Children's Research Centre.
Journal of lipid research.J Lipid Res.2013 Jan;54(1):63-70. doi: 10.1194/jlr.M028035. Epub 2012 Oct 21.
Fas (CD95) is a member of the tumor necrosis factor (TNF) receptor superfamily and plays a crucial role in the induction of apoptosis. However, like TNF, Fas can induce nonapoptotic signaling pathways. We previously demonstrated that mice lacking Fas specifically in adipocytes are partly protected f
PMID 23089915

Type-I Interferon is Critical for FasL Expression on Lung Cells to Determine the Severity of Influenza

Fujikura Daisuke,Chiba Satoko,Muramatsu Daisuke,Kazumata Mika,Nakayama Yosuke,Kawai Taro,Akira Shizuo,Kida Hiroshi,Miyazaki Tadaaki
PLoS One 8(2), e55321, 2013-02-08
… FasL is a specific ligand of Fas, which is a type-I transmembrane protein to induce cell death. … More importantly, it was also reported that functional mutation of the FasL gene protects the host against influenza A virus infection. … These observations suggest that induction of FasL signal is functionally associated with the severity of influenza. …
NAID 120005228345

3-Oxoolean-12-en-27-oic Acid Isolated from Aceriphyllum rossii Induces Caspase-8-Dependent Apoptosis in Human Promyelocytic Leukemia HL-60 Cells(Pharmacognosy)

Kim Sung-Su,Won So-Jung,Kim Nam Jae [他],YOO Jae Kuk,BAE KiHwan,LEE Kyung-Tae
Biological & pharmaceutical bulletin 32(1), 91-98, 2009-01-01
… Furthermore, 3-OA increased Fas-related protein contents and the mRNA expressions of Fas ligand (FasL), Fas, and Fas-associated death domain (FADD). … Preincubation with anti-Fas or anti-FasL blocking antibodies completely prevented 3-OA-induced apoptosis. … Taken together, these results suggest that 3-oxoolean-12-en-27-oic acid induces apoptosis by activating caspase-8 via FasL-stimulated death receptor signaling. …
NAID 110007021748

Inhibition of Insulin-like Growth Factor 1 Receptor Signaling Enhanced Silibinin-Induced Activation of Death Receptor and Mitochondrial Apoptotic Pathways in Human Breast Cancer MCF-7 Cells

Wang Hong-jun,Tashiro Shin-ichi,Onodera Satoshi [他],IKEJIMA Takashi
Journal of pharmacological sciences 107(3), 260-269, 2008-07-20
… Expressions of Fas ligand (FasL), Fas-associated death domain protein (FADD), and Bax were significantly up-regulated in silibinin-treated cells, whilst silibinin induced a conspicuous translocation of Bax to mitochondria and release of cytochrome <i>c</i> … It was also found that silibinin markedly decreased protein expression of SIRT1, a mammalian homologue of yeast Sir2, which was proved to have a role in sequestering Bax away from mitochondria. …
NAID 10024321265