WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
informal term for information; "give me the gen on your new line of computers"

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1. 頭蓋骨縫合早期癒合症候群 craniosynostosis syndromes
2. 外陰部異常を有する幼児の評価 evaluation of the infant with ambiguous genitalia
3. 再発性または転移性子宮体癌の治療 treatment of recurrent or metastatic endometrial cancer
4. 頭蓋骨縫合早期癒合症の概要 overview of craniosynostosis
5. 肺移植：死亡ドナーの評価およびマネージメント lung transplantation deceased donor evaluation and management

Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets.

Qian Z1, Zhu G, Tang L, Wang M, Zhang L, Fu J, Huang C, Fan S, Sun Y, Lv J, Dong H, Gao B, Su X, Yu D, Zang J, Zhang X, Ji J, Ji Q.
Genes, chromosomes & cancer.Genes Chromosomes Cancer.2014 Nov;53(11):883-94. doi: 10.1002/gcc.22196. Epub 2014 Jun 17.
Gastric cancer is the second leading cause of death from cancer worldwide, with an approximately 20% 5-year survival rate. To identify molecular subtypes associated with the clinical prognosis, in addition to genetic aberrations for potential targeted therapeutics, we conducted a comprehensive whole
PMID 24935174

Mutually exclusive FGFR2, HER2, and KRAS gene amplifications in gastric cancer revealed by multicolour FISH.

Das K1, Gunasegaran B2, Tan IB3, Deng N2, Lim KH4, Tan P5.
Cancer letters.Cancer Lett.2014 Oct 28;353(2):167-75. doi: 10.1016/j.canlet.2014.07.021. Epub 2014 Jul 30.
Gastric cancer (GC) is a major cause of global cancer mortality. Previous genomic studies have reported that several RTK-RAS pathway components are amplified in GC, with individual tumours often amplifying one component and not others ("mutual exclusivity"). Here, we sought to validate these finding
PMID 25086186

Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity.

Yasuda K1, Torigoe T1, Mariya T2, Asano T2, Kuroda T3, Matsuzaki J1, Ikeda K4, Yamauchi M4, Emori M1, Asanuma H5, Hasegawa T5, Saito T3, Hirohashi Y1, Sato N1.
Laboratory investigation; a journal of technical methods and pathology.Lab Invest.2014 Oct 20. doi: 10.1038/labinvest.2014.122. [Epub ahead of print]
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are defined as a small population of cells within cancer that contribute to cancer initiation and progression. Cancer-associated fibroblasts (CAFs) are stromal fibroblasts surrounding tumor cells, and they have important roles in tumor gro
PMID 25329002

A novel insertion in the FGFR2 gene in a patient with Crouzon phenotype and sacrococcygeal tail

Evaluation of the Quality of Porcine Somatic Cell Nuclear Transfer Embryo by Gene Transcription Profiles

MIYAZAKI Koji,TOMII Ryo,KUROME Mayuko,UEDA Hideto,HIRAKAWA Kazumasa,UENO Satoshi,HIRUMA Katsumi,NAGASHIMA Hiroshi
Journal of Reproduction and Development 51(1), 123-131, 2005
… This study aimed to evaluate the quality of porcine somatic cell nuclear transfer (SCNT) embryos by examining its gene transcription patterns. …
NAID 130000054761