Eotaxin 2

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Chelidonine, a principal isoquinoline alkaloid of Chelidonium majus, attenuates eosinophilic airway inflammation by suppressing IL-4 and eotaxin-2 expression in asthmatic mice.

Kim SH1, Hong JH2, Lee YC3.
Pharmacological reports : PR.Pharmacol Rep.2015 Dec;67(6):1168-77. doi: 10.1016/j.pharep.2015.04.013. Epub 2015 May 11.
BACKGROUND: Chelidonine, a major bioactive, isoquinoline alkaloid ingredient in Chelidonium majus, exhibits anti-inflammatory and other pharmacological properties. However, its molecular mechanisms in asthma remain unclear. In this work we investigated chelidonine's effect and mechanism in airway in
PMID 26481537

Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome.

Landi A1, Broadhurst D2, Vernon SD3, Tyrrell DL4, Houghton M5.
Cytokine.Cytokine.2015 Nov 23;78:27-36. doi: 10.1016/j.cyto.2015.11.018. [Epub ahead of print]
Recently, differences in the levels of various chemokines and cytokines were reported in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) as compared with controls. Moreover, the analyte profile differed between chronic ME/CFS patients of long duration versus patients with d
PMID 26615570

Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy.

Li H1, Meng YH1, Shang WQ1, Liu LB1, Chen X1, Yuan MM1, Jin LP2, Li MQ3, Li DJ4.
Reproduction (Cambridge, England).Reproduction.2015 Nov;150(5):417-27. doi: 10.1530/REP-15-0119. Epub 2015 Aug 27.
Chemokine CCL24, acting through receptor CCR3, is a potent chemoattractant for eosinophil in allergic diseases and parasitic infections. We recently reported that CCL24 and CCR3 are co-expressed by trophoblasts in human early pregnant uterus. Here we prove with evidence that steroid hormones estradi
PMID 26316550

Suppression of eosinophilia by Petalonia binghamiae polysaccharides may relate to their eotaxin-binding ability

Wogonin, a plant flavone from <i>Scutellariae</i> radix, attenuated ovalbumin-induced airway inflammation in mouse model of asthma via the suppression of IL-4/STAT6 signaling