WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
the 5th letter of the Roman alphabet (同)e

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Sanders RW.SourceLaboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands. r.w.sanders@amc.uva.nl
BMC biology.BMC Biol.2013 Dec 7;10:99. doi: 10.1186/1741-7007-10-99.
In the absence of a vaccine or a cure, identification of novel HIV-1 inhibitors remains important. A paper in Retrovirology describes a rationally designed bi-specific protein that irreversibly damages the viral envelope glycoprotein complex via a two-punch mechanism. In contrast to traditional drug
PMID 23216951

Low complexity regions (LCRs) contribute to the hypervariability of the HIV-1 gp120 protein.

María Velasco A, Becerra A, Hernández-Morales R, Delaye L, Jiménez-Corona ME, Ponce-de-Leon S, Lazcano A.SourceFacultad de Ciencias, UNAM, Ciudad Universitaria, Apdo. Postal 70-407, México D. F. 04510, Mexico; Laboratorios de Biológicos y Reactivos de México, Amores 1240, Colonia Del Valle, México D. F. 03100, Mexico.
Journal of theoretical biology.J Theor Biol.2013 Dec 7;338:80-6. doi: 10.1016/j.jtbi.2013.08.039. Epub 2013 Sep 8.
Low complexity regions (LCRs) are sequences of nucleic acids or proteins defined by a compositional bias. Their occurrence has been confirmed in sequences of the three cellular lineages (Bacteria, Archaea and Eucarya), and has also been reported in viral genomes. We present here the results of a det
PMID 24021867

Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice.

Perron H, Dougier-Reynaud HL, Lomparski C, Popa I, Firouzi R, Bertrand JB, Marusic S, Portoukalian J, Jouvin-Marche E, Villiers CL, Touraine JL, Marche PN.SourceGeneuro, Plan-les-Ouates, Geneva, Switzerland ; Geneuro-Innovation, Lyon, France ; Université Lyon-1, Lyon, France.
PloS one.PLoS One.2013 Dec 6;8(12):e80128. doi: 10.1371/journal.pone.0080128.
Multiple sclerosis (MS) is a complex multifactorial disease of the central nervous system (CNS) for which animal models have mainly addressed downstream immunopathology but not potential inducers of autoimmunity. In the absence of a pathogen known to cause neuroinflammation in MS, Mycobacterial lysa
PMID 24324591

The NP-2 cell system for analyses of the coreceptor usage of human and simian immunodeficiency viruses

Hoshino Hiroo
北関東医学 62(1), 1-14, 2012
… The cell tropi sm of HIV and the det erm inants of a cell'ssusceptibility to HIV infection have been mainly explained by thecombination of HIV surface proteins, Env, and expression ofCD4 andcoreceptors on the target cells. …
NAID 130002096501