WordNet

a thin pliable sheet of material
a pliable sheet of tissue that covers or lines or connects the organs or cells of animals or plants (同)tissue layer

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(生物の)膜,皮膜

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/12/10 16:13:49」(JST)

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Descemet's membrane is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea. It is composed of a different kind of collagen (Type IV)^[1] than the stroma. The endothelial layer is located at the posterior of the cornea. Descemet's membrane, as the basement membrane for the endothelial layer, is secreted by the single layer of squamous epithelial cells that compose the endothelial layer of the cornea.

Its thickness ranges from 3 μm at birth to 8-10 μm in adults.^[2]

It is also known as the Posterior limiting lamina, posterior elastic lamina, lamina elastica posterior, and membrane of Demours. It was named after French physician Jean Descemet (1732–1810).

Significant damage to the membrane may require a corneal transplant as the endothelial cells depend on it for support and cannot re-grow after injury without it.^{[citation needed]}

References

Histology A text and atlas. Michael H.Ross and Wojciech Pawlina 5th Edition 2006

^ http://emedicine.medscape.com/article/1197057-overview
^ Johnson DH, Bourne WM, Campbell RJ: The ultrastructure of Descemet's membrane. I. Changes with age in normal cornea. Arch Ophthalmol 100:1942, 1982

External links

BU Histology Learning System: 08002loa
Descemet+membrane at the US National Library of Medicine Medical Subject Headings (MeSH)
Diagram at dryeyezone.com

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English Journal

Correlation between visual acuity and interface reflectivity measured by pentacam following DSAEK.

Heinzelmann S, Böhringer D, Maier PC, Reinhard T.Author information University Eye Hospital, Freiburg im Breisgau, Germany.AbstractPurpose: Descemet-stripping automated endothelial keratoplasty (DSAEK) is an advanced method of lamellar endothelial keratoplasty. In comparison with penetrating keratoplasty, visual rehabilitation seems to be faster. Final visual outcome of DSAEK, however, seems to be limited, especially in comparison with Descemet membrane endothelial keratoplasty (DMEK). DSAEK cases without graft failure often do not show any definite correlate for the reduced optical performance. In this study, we tried to correlate visual acuity following DSAEK with interface reflectivity as measured by a rotating Scheimpflug system. Methods: We examined 14 eyes of 13 patients with the pentacam for 2-11 months following DSAEK. Reflectivity of the interface region in the centre of the optical axis as well as central corneal thickness was determined. Statistical correlation between interface reflectivity and best spectacle-corrected visual acuity, central corneal thickness and follow-up time was drawn (multifactorial linear regression analysis). Results: Statistically significant correlation between interface reflectivity and BSCVA as well as follow-up time was found. Reflectivity was highest in regions of interface (metal) particles. There was no statistically significant correlation between interface reflectivity and central corneal thickness. Conclusion: We present a measurable correlate for reduced visual outcome following DSAEK despite a clear graft. Inverse correlation between interface reflectivity and best spectacle-corrected visual acuity (BSCVA) indicates that irregularities or scarring in the interface region may influence the optical quality following DSAEK.
Acta ophthalmologica.Acta Ophthalmol.2014 Feb;92(1):e1-4. doi: 10.1111/aos.12217. Epub 2013 Jul 26.
Purpose: Descemet-stripping automated endothelial keratoplasty (DSAEK) is an advanced method of lamellar endothelial keratoplasty. In comparison with penetrating keratoplasty, visual rehabilitation seems to be faster. Final visual outcome of DSAEK, however, seems to be limited, especially in comp
PMID 23889769

Intraoperative Anterior Segment Optical Coherence Tomography: A Novel Assessment Tool during Deep Anterior Lamellar Keratoplasty.

De Benito-Llopis L1, Mehta JS2, Angunawela RI3, Ang M4, Tan DT5.Author information 1Singapore National Eye Centre, Singapore. Electronic address: lauradeb@hotmail.com.2Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Department of Ophthalmology, National University Health System, Singapore; Duke-NUS Graduate Medical School, Singapore.3Singapore National Eye Centre, Singapore.4Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore.5Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Department of Ophthalmology, National University Health System, Singapore.AbstractPURPOSE: To describe the use of high-resolution anterior segment optical coherence tomography (AS-OCT) during deep anterior lamellar keratoplasty (DALK).
American journal of ophthalmology.Am J Ophthalmol.2014 Feb;157(2):334-341.e3. doi: 10.1016/j.ajo.2013.10.001. Epub 2013 Oct 8.
PURPOSE: To describe the use of high-resolution anterior segment optical coherence tomography (AS-OCT) during deep anterior lamellar keratoplasty (DALK).DESIGN: Prospective case series.METHODS: At the Singapore National Eye Centre we performed sequential intraoperative AS-OCT scans using iVue 100-2
PMID 24332371

Corneal changes in xeroderma pigmentosum: a clinicopathologic report.

Chaurasia S1, Mulay K2, Ramappa M3, Sangwan V3, Murthy S3, Nair R4, Vemuganti G5.Author information 1Cornea and Anterior Segment Services, L.V. Prasad Eye Institute, Hyderabad, India. Electronic address: sunita@lvpei.org.2Ocular Pathology Services, L.V. Prasad Eye Institute, Hyderabad, India.3Cornea and Anterior Segment Services, L.V. Prasad Eye Institute, Hyderabad, India.4School of Medical Sciences, University of Hyderabad, Hyderabad, India.5Ocular Pathology Services, L.V. Prasad Eye Institute, Hyderabad, India; School of Medical Sciences, University of Hyderabad, Hyderabad, India.AbstractPURPOSE: To report the clinicopathologic features of corneal involvement in patients with xeroderma pigmentosum.
American journal of ophthalmology.Am J Ophthalmol.2014 Feb;157(2):495-500.e2. doi: 10.1016/j.ajo.2013.10.016. Epub 2013 Nov 6.
PURPOSE: To report the clinicopathologic features of corneal involvement in patients with xeroderma pigmentosum.DESIGN: Retrospective review of corneal histopathology.METHODS: Thirteen corneal specimens of 11 patients with xeroderma pigmentosum who underwent keratoplasty (lamellar/full-thickness) fo
PMID 24211864

Japanese Journal

CLINICAL INVESTIGATION : Histologic findings of recipient corneas obtained via deep anterior lamellar keratoplasty

Ishimaru Shimpei,Senoo Tadashi,Gotoh Norihito [他]
Japanese journal of ophthalmology : the official international journal of the Japanese Ophthalmological Society 58(4), 342-347, 2014-07
NAID 40020124503

白内障手術に伴う広汎な Descemet 膜剥離を両眼に生じSF_6ガス前房内注入を要した1例

魚谷竜,井上幸次
あたらしい眼科 = Journal of the eye 30(5), 699-702, 2013-05-30
NAID 10031176178

白内障手術に伴う広汎なDescemet膜剝離を両眼に生じSF₆ガス前房内注入を要した1例

魚谷竜,井上幸次
あたらしい眼科 30(5), 699-702, 2013-05
NAID 40019691622

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★リンクテーブル★

リンク元	「デスメ膜」
関連記事	「membrane」

「デスメ膜」

Descemet's membrane
	Vertical section of human cornea from near the margin. (Waldeyer.) Magnified.; 1. Epithelium.; 2. Anterior elastic lamina.; 3. substantia propria.; 4. Posterior elastic lamina.; (Descemet's membrane); 5. Endothelium of the anterior chamber.; a. Oblique fibers in the anterior layer of the substantia propria.; b. Lamellæ the fibers of which are cut across, producing a dotted appearance.; c. Corneal corpuscles appearing fusiform in section.; d. Lamellæ the fibers of which are cut longitudinally.; e. Transition to the sclera, with more distinct fibrillation, and surmounted by a thicker epithelium.; f. Small bloodvessels cut across near the margin of the cornea.
Latin	l. limitans posterior corneae
Gray's	subject #225 1008

　　[★]

英: Descemet membrane
同: Descemet膜、後境界板 posterior limiting layer lamina limitans posterior
関: 角膜

「membrane」

　　[★]

n.

膜、メンブラン

[1] ttp://emedicine.medscape.com/article/1197057-overview

[2] Johnson DH, Bourne WM, Campbell RJ: The ultrastructure of Descemet's membrane. I. Changes with age in normal cornea. Arch Ophthalmol 100:1942, 1982

Descemet's membrane

Vertical section of human cornea from near the margin. (Waldeyer.) Magnified. 1. Epithelium. 2. Anterior elastic lamina. 3. substantia propria. 4. Posterior elastic lamina. (Descemet's membrane) 5. Endothelium of the anterior chamber. a. Oblique fibers in the anterior layer of the substantia propria. b. Lamellæ the fibers of which are cut across, producing a dotted appearance. c. Corneal corpuscles appearing fusiform in section. d. Lamellæ the fibers of which are cut longitudinally. e. Transition to the sclera, with more distinct fibrillation, and surmounted by a thicker epithelium. f. Small bloodvessels cut across near the margin of the cornea.
Latin	l. limitans posterior corneae
Gray's	subject #225 1008

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Descemet membrane