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- 1. HIV感染患者における心血管リスク（脂質異常症を含む）のマネージメント management of cardiovascular risk including dyslipidemia in the hiv infected patient
English Journal
- Drug metabolism enzymes in a steatotic model of rat treated with a high fat diet and a low dose of streptozotocin.
- Vornoli A1, Pozzo L2, Della Croce CM2, Gervasi PG1, Longo V3.
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.Food Chem Toxicol.2014 Aug;70:54-60. doi: 10.1016/j.fct.2014.04.042. Epub 2014 May 9.
- Herein we have characterized CYPs and antioxidant enzymes in a new steatotic rat model induced with a high fat diet (HFD) combined with a low dose of streptozotocin (STZ). This model was recently put forward in order to better replicate the NAFLD human pathology. HFD/STZ rats developed hyperglycemia
- PMID 24815820
- Role of 20-HETE in the impaired myogenic and TGF responses of the Af-Art of Dahl Salt-sensitive rats.
- Ge Y1, Murphy SR2, Fan F3, Williams JM3, Falck JR4, Liu R3, Roman RJ5.
- American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2014 Jul 9. pii: ajprenal.00273.2014. [Epub ahead of print]
- Previous studies have indicated that a deficiency in the renal formation of 20-hydroxyeicosatetraenoic acid (20-HETE) in Dahl S (SS) rats contributes to the development of hypertension. The present study examined whether 20-HETE production is also reduced in the renal vasculature and if the defect i
- PMID 25007877
- Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
- Zhang Y1, Hoda MN1, Zheng X2, Li W3, Luo P4, Maddipati KR5, Seki T1, Ergul A1, Wang MH6.
- American journal of physiology. Regulatory, integrative and comparative physiology.Am J Physiol Regul Integr Comp Physiol.2014 Jul 2. pii: ajpregu.00422.2013. [Epub ahead of print]
- 20-Hydroxyeicosatetraenoic acid (20-HETE), Cyp4a-derived eicosanoid, is a lipid mediator that promotes tumor growth as well as causing detrimental effects in cerebral circulation. We determined whether concurrent inhibition of cyclooxygenase-2 (COX-2) and 20-HETE affects colon tumor growth and ische
- PMID 24990856
Japanese Journal
- Kidney Cadmium Toxicity, Diabetes and High Blood Pressure: The Perfect Storm
- The Tohoku Journal of Experimental Medicine 241(1), 65-87, 2017
- NAID 130005306321
- Interactions Among <i>CYP2C8</i>, <i>EPHX2</i>, and <i>CYP4A11</i> Variants and CYP Plasma Metabolite Levels in Ischemic Stroke
- Ｊｏｕｒｎａｌ ｏｆ Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ ａｎｄ Ｔｈｒｏｍｂｏｓｉｓ 23(11), 1286-1293, 2016
- NAID 130005268298
- フタル酸ビス（2-エチルヘキシル）およびフェノバルビタール反復投与による生体内ホルモン変動の作用機序検討
- 日本毒性学会学術年会 43.1(0), P-267, 2016
- NAID 130005260824
Related Links
- ... (AA) by the cytochrome P450 CYP2C epoxygenase and CYP4A ω-hydroxylase gene subfamilies, have been identified as potent and high-affinity ligands of PPARα in vitro and as PPARα activators in transient we demonstrate ...
- 1. J Biol Chem. 1998 Nov 20;273(47):31581-9. Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. Kroetz DL, Yook P, Costet P, Bianchi P, Pineau T. ...
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★リンクテーブル★
| リンク元 | 「alkane 1-monooxygenase」 |
| 拡張検索 | 「CYP4Aタンパク質」 |
「alkane 1-monooxygenase」
- 関
- CYP4A
「CYP4Aタンパク質」
- 英
- (n