WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

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Ovarian cancer stem-like cells differentiate into endothelial cells and participate in tumor angiogenesis through autocrine CCL5 signaling.

Tang S1, Xiang T2, Huang S1, Zhou J1, Wang Z1, Xie R3, Long H4, Zhu B5.
Cancer letters.Cancer Lett.2016 Jun 28;376(1):137-47. doi: 10.1016/j.canlet.2016.03.034. Epub 2016 Mar 23.
Cancer stem cells (CSCs) are well known for their self-regeneration and tumorigenesis potential. In addition, the multi-differentiation potential of CSCs has become a popular issue and continues to attract increased research attention. Recent studies demonstrated that CSCs are able to differentiate
PMID 27033454

Immunohistochemical differentiation of eosinophilic esophageal myositis from eosinophilic esophagitis.

Sato H1, Nakajima N1, Hasegawa G2, Kawata Y1, Sato Y1, Suzuki K1, Honma T3, Terai S1.
Journal of gastroenterology and hepatology.J Gastroenterol Hepatol.2016 Jun 5. doi: 10.1111/jgh.13466. [Epub ahead of print]
BACKGROUND AND AIM: Eosinophilic esophagitis (EoE) is a Th2-mediated allergic disease of the esophageal epithelium, associated with antigen. We previously reported a case series for eosinophilic esophageal myositis (EoEM)-a novel eosinophilic gastrointestinal disorder (EoGID) defined as eosinophilic
PMID 27262491

Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells.

Huang G1, Tao L1, Shen S2, Chen L1.
Scientific reports.Sci Rep.2016 Jun 2;6:27152. doi: 10.1038/srep27152.
Tumor hypoxia is one of the important features of lung adenocarcinoma. Chemokines might mediate the effects caused by tumor hypoxia. As confirmed in tumor tissue and serum of patients, CC chemokine 28 (CCL28) was the only hypoxia induced chemokine in lung adenocarcinoma cells. CCL28 could promote tu
PMID 27250766

A Novel CC-Chemokine Receptor 3 Antagonist, Ki19003, Inhibits Airway Eosinophilia and Subepithelial/Peribronchial Fibrosis Induced by Repeated Antigen Challenge in Mice

Komai Masato,Tanaka Hiroyuki,Nagao Koichi [他],ISHIZAKI Masayuki,KAJIWARA Daisuke,MIURA Toru,OHASHI Hiroshi,HABA Tomoko,KAWAKAMI Kazuki,SAWA Eiji,YOSHIE Osamu,INAGAKI Naoki,NAGAI Hiroichi
Journal of pharmacological sciences 112(2), 203-213, 2010-02-20
… CC-chemokine receptor 3 (CCR3) is a chemokine receptor for which major ligands, CC-chemokine ligand (CCL) 11, CCL24, and CCL26, are known to be involved in chemotaxis for eosinophils. … In the present study, we evaluated the effect of a low molecular weight CCR3-receptor antagonist, Ki19003 (4-[[5-(2,4-dichlorobenzylureido)pentyl][1-(4-chlorophenyl)ethyl]amino]butanoic acid), on airway remodeling in a mouse model of allergic asthma. …
NAID 10029888930

Production and Regulation of Eotaxin-2/CCL24 in a Differentiated Human Leukemic Cell Line, HT93(Biochemistry)

Yoshida Naomi,Aizu-Yokota Eriko,Sonoda Yoshiko [他],MORIWAKI Yasuhiro,KISHI Kenji,KASAHARA Tadashi
Biological & pharmaceutical bulletin 30(10), 1826-1832, 2007-10-01
… Both CD11b and CC chemokine receptor, CCR3 expression were upregulated, while CD71 expression was downregulated by ATRA or ATRA+IL-5. … Since only 20 to 30% cells incubated with ATRA became positive for CCR3, CCR3^+ population was enriched by a magnetic activated cell sorter (MACS). …
NAID 110006436358