ブラストミセス・デルマティティディス
- 関
- B. dermatitidis、Blastomyces
WordNet
- genus of pathogenic yeastlike fungi (同)genus Blastomyces
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/11/15 19:05:03」(JST)
[Wiki en表示]
Blastomyces |
|
Blastomyces dermatitidis |
Scientific classification |
Kingdom: |
Fungi |
Phylum: |
Ascomycota |
Class: |
Ascomycetes |
Subclass: |
Incertae sedis |
Order: |
Incertae sedis |
Family: |
Incertae sedis |
Genus: |
Blastomyces |
Blastomyces is a fungal genus responsible for the medical condition blastomycosis.
The most well known species of the genus is Blastomyces dermatitidis. B. dermatitidis is a dimorphic fungal pathogen, found primarily in the Mid-West and Northern United States and Canada. It exists in the soil in a filamentous form that produces spores directly upon the wall of the hyphae, lacking any kind of fruiting body to aid in aerosolization/dissemination of the spores. The natural reservoir of this organism in the environment is not clearly defined, but it seems to be associated with rivers and lakes. Blastomyces is endemic to the Mississippi and Ohio river valleys and the vicinity of the Great Lakes. Outbreaks of blastomycosis are often associated with disruptions of the soil that might lead to the artificial elevation of spore and/or hyphal fragments in the air. These agents infect human and animal hosts when they are inhaled. At the elevated temperature of 37°C in a host, the fungus undergoes a phase transition to the pathogenic yeast form. Yeast form cells multiply in the lung and may cause disease in immuno-competent hosts, sometimes disseminating to the skin, central nervous system and bones. Blastomycosis is more commonly diagnosed in pets than in humans, especially dogs.
References
Klein, B. S., Vergeront, J. M., Weeks, R. J. (1986) "Isolation of Blastomyces dermatitidis in soil associated with a large outbreak of blastomycosis in Wisconsin". N. Engl. J. Med. 314, 529-534.
Disalvo, A.F. (1992) "Ecology of Blastomyces dermatitidis" in: Blastomycosis (Al-Doory, Y. and Disalvo, A. F., eds), 43-73, Plenum Publishing Corp.
External links
- Blastomyces at the US National Library of Medicine Medical Subject Headings (MeSH)
- http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dimorphic_Pathogens/Blastomyces/
- http://pathmicro.med.sc.edu/mycology/mycology-6.htm
UpToDate Contents
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English Journal
- Interleukin 1 Enhances Vaccine-Induced Antifungal T-Helper 17 Cells and Resistance Against Blastomyces dermatitidis Infection.
- Wüthrich M, Lebert V, Galles K, Hu-Li J, Ben-Sasson SZ, Paul WE, Klein BS.SourceDepartment of Pediatrics.
- The Journal of infectious diseases.J Infect Dis.2013 Jul 11. [Epub ahead of print]
- Vaccine-induced T-helper 17 (Th17) cells are necessary and sufficient to protect against fungal infection. Although live fungal vaccines are efficient in driving protective Th17 responses and immunity, attenuated fungi may not be safe for human use. Heat-inactivated formulations and subunit vaccines
- PMID 23788728
- Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling.
- Marty AJ, Wüthrich M, Carmen JC, Sullivan TD, Klein BS, Cuomo CA, Gauthier GM.SourceDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin - Madison, 1550 Linden Drive, Microbial Sciences Building, Room 4335A, Madison, WI 53706, USA. Electronic address: ajvanden@wisc.edu.
- Fungal genetics and biology : FG & B.Fungal Genet Biol.2013 Jul;56:1-8. doi: 10.1016/j.fgb.2013.03.001. Epub 2013 Mar 14.
- Blastomyces dermatitidis belongs to a group of thermally dimorphic fungi that grow as sporulating mold in the soil and convert to pathogenic yeast in the lung following inhalation of spores. Knowledge about the molecular events important for fungal adaptation and survival in the host remains limited
- PMID 23499858
- Structure and Function of a Fungal Adhesin that Binds Heparin and Mimics Thrombospondin-1 by Blocking T Cell Activation and Effector Function.
- Brandhorst TT, Roy R, Wüthrich M, Nanjappa S, Filutowicz H, Galles K, Tonelli M, McCaslin DR, Satyshur K, Klein B.SourceDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
- PLoS pathogens.PLoS Pathog.2013 Jul;9(7):e1003464. doi: 10.1371/journal.ppat.1003464. Epub 2013 Jul 11.
- Blastomyces adhesin-1 (BAD-1) is a 120-kD surface protein on B. dermatitidis yeast. We show here that BAD-1 contains 41 tandem repeats and that deleting even half of them impairs fungal pathogenicity. According to NMR, the repeats form tightly folded 17-amino acid loops constrained by a disulfide bo
- PMID 23853587
Japanese Journal
- Adult hemophagocytic lymphohistiocytosis with severe pulmonary hypertension and a novel perforin gene mutation
- GERARD Lauren M.,XING Katharine,SHERIFI Ines,GRANTON John,BARTH David,ABDELHALEEM Mohamed,BERGERON Catherine,WEITZMAN Sheila,CSERTI-GAZDEWICH Christine
- International journal of hematology 95(4), 445-450, 2012-04-01
- NAID 10030632732
- In vitro activities of voriconazole, itraconazole, and amphotericin B against Blastomyces dermatitidis, Coccidioides immitis, and Histoplasma capsulatum
- Extensive Extraaxial Blastomycosis Granuloma at the Skull Base : Case Report
- GOEL Atul,BHAYANI Rajan,DESAI Anand P.,GOEL Naina
- Neurologia medico-chirurgica 36(6), 393-395, 1996-06-15
- … A 37-year-old female presented with a rare case of intradural, extraaxial Blastomyces dermatitidis granuloma involving a large part of the skull base. …
- NAID 110002278809
Related Links
- 15 Mar 2012 ... Blastomycosis is a disease caused by the fungus Blastomyces dermatitidis. The fungus lives in moist soil and in association with decomposing organic matter such as wood and leaves. Lung infection can occur after a person ...
- The most well known species of the genus is Blastomyces dermatitidis, responsible for the medical condition blastomycosis in humans and other animals. Other former speices have been redefined to other genuses. For example, Blastomyces ...
Related Pictures
![Blastomyces dermatitidis - right in the](https://1mg.info/0/a/h/1371.jpg)
![Blastomyces dermatitidis](https://1mg.info/0/e/3/0722.jpg)
![Blastomyces dermatitidis - unbranched](https://1mg.info/0/e/3/0723.jpg)
![Blastomyces dermatitidis - Conidia seen](https://1mg.info/0/e/3/0724.jpg)
![Blastomyces dermatitidis - Large budding](https://1mg.info/0/e/3/0725.jpg)
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- 関
- Blastomyces dermatitidis
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- Blastomyces dermatitidis、B. dermatitidis
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