Andes virus

アンデスウイルス

関

hantavirus

WordNet

1. a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
2. (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
3. a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
4. a mountain range in South America running 5000 miles along the Pacific coast

PrepTutorEJDIC

1. ビールス,ろ過性病原体
2. 《the ~》アンデス山脈(南米西部の大山脈)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/03/08 20:51:39」(JST)

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Andes virus
Virus classification
Group:	Group V ((-)ssRNA)
Family:	Bunyaviridae
Genus:	Hantavirus
Species:	Andes virus

Andes virus (ANDV) is a hantavirus, which, in South America, is a major causative agent of Hantavirus cardiopulmonary syndrome (HCPS or HPS).

Background

Due to the Andes virus infection, HCPS has a case fatality percentage of about 25–35% in Argentina and of 37% in Chile. ANDV, lineage ANDV-Sout, is the only hantavirus for which a person-to-person transmission has been described. Several ANDV strains are co-circulating in Argentina, e.g. Bermejo, Lechiguanas, Maciel, Oran and Pergamino, whereas HCPS cases were also reported in Bolivia, Brazil, Paraguay and Uruguay. Only for Chile and Argentina can they be strictly associated with ANDV.

In Argentina and Chile, the long-tailed rice rat, Oligoryzomys longicaudatus, and other species of the genus Oligoryzomys represent the reservoir for ANDV. Another unique characteristic of ANDV is the availability of an animal model. ANDV causes lethal disease in the Syrian Hamster that closely models the course of disease progression in humans, including a rapid progression from first symptoms to death, including fluid in the pleural cavity and the histopathology of the lungs and spleen. Lethality of ANDV in hamsters is not true of all HCPS viruses, as challenge with Sin Nombre virus shows no symptoms of disease. The availability of this model allows for the study of various drugs and other treatments that may have an impact on the treatment of all HCPS-causing hantavirus infections.

See also

• Hantavirus
• Sin Nombre virus

References

Using Wikipedia for research

External links

• CDC's Hantavirus Technical Information Index page
• Viralzone: Hantavirus
• Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae
• Occurrences and deaths in North and South America

UpToDate Contents

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• 1. ハンタウイルス感染の疫学および診断 epidemiology and diagnosis of hantavirus infections
• 2. ハンタウイルス心肺症候群 hantavirus cardiopulmonary syndrome
• 3. ハンタウイルス感染による腎疾患（腎症候性出血熱） renal involvement with hantavirus infection hemorrhagic fever with renal syndrome
• 4. ハンタウイルス感染の病因 pathogenesis of hantavirus infections
• 5. 東アジアへの旅行によって感染する可能性のある疾患 diseases potentially acquired by travel to east asia

English Journal

• Epidemiology of Hantavirus infections in humans: A comprehensive, global overview.

• Watson DC, Sargianou M, Papa A, Chra P, Starakis I, Panos G.Author information Division of Infectious Diseases, Department of Internal Medicine, Patras University General Hospital , Patras , Greece .AbstractAbstract Hantaviruses comprise an emerging global threat for public health, affecting about 30 000 humans annually. Infection may lead to Hantavirus pulmonary syndrome (HPS) in the Americas and hemorrhagic fever with renal syndrome (HFRS) in the Europe and Asia. Humans are spillover hosts, acquiring infection primarily through the inhalation of aerosolized excreta from infected rodents and insectivores. Risk factors for infection include involvement in outdoor activities, such as rural- and forest-related activities, peridomestic rodent presence, exposure to potentially infected dust and outdoor military training; prolonged, intimate contact with infected individuals promotes transmission of Andes virus, the only Hantavirus known to be transmitted from human-to-human. The total number of Hantavirus case reports is generally on the rise, as is the number of affected countries. Knowledge of the geographical distribution, regional incidence and associated risk factors of the disease are crucial for clinicians to suspect and diagnose infected individuals early on. Climatic, ecological and environmental changes are related to fluctuations in rodent populations, and subsequently to human epidemics. Thus, prevention may be enhanced by host-reservoir control and human exposure prophylaxis interventions, which likely have led to a dramatic reduction of human cases in China over the past decades; vaccination may also play a role in the future.
• Critical reviews in microbiology.Crit Rev Microbiol.2014 Aug;40(3):261-72. doi: 10.3109/1040841X.2013.783555. Epub 2013 Apr 22.
• Abstract Hantaviruses comprise an emerging global threat for public health, affecting about 30 000 humans annually. Infection may lead to Hantavirus pulmonary syndrome (HPS) in the Americas and hemorrhagic fever with renal syndrome (HFRS) in the Europe and Asia. Humans are spillover hosts, acquiri
• PMID 23607444

• Programmed hepatocytes cell death associated with FLIP downregulation in response to extracellular PreS1/2.

• Rojas MD, Peterson DL, Barboza L, Terán-Ángel G, Labastida-Moreno CA, Berrueta L, Salmen S.Author information Instituto de Inmunología Clínica, Universidad de Los Andes, Merida, Venezuela.AbstractChronic hepatitis B virus (HBV) infection involves liver damage resulting in continuous cell injury and death. During HBV infection, hepatocytes exhibit changes in death receptor expression and in their susceptibility to death. These changes are observed not only in infected cells but also in bystander cells. Because excess viral surface protein (HBsAg) is secreted in large amounts as soluble particles containing preS proteins, the role of soluble preS1/2 in hepatocyte (HepG2) death modulation is an important issue to be explored. An increase of cell death induced by preS1/2 was observed. Also, cell death was associated with the down-regulation of FLIP and activation of caspase 8, caspase 9, and BID. Additionally, hepatocytes exhibited a sensitization to death mediated by the Fas receptor. These results, may contribute to understanding the role of envelope proteins (preS1/2) in the pathogenesis of HBV infection. J. Med. Virol. 86:496-504, 2014. © 2013 Wiley Periodicals, Inc.
• Journal of medical virology.J Med Virol.2014 Mar;86(3):496-504. doi: 10.1002/jmv.23859. Epub 2013 Nov 19.
• Chronic hepatitis B virus (HBV) infection involves liver damage resulting in continuous cell injury and death. During HBV infection, hepatocytes exhibit changes in death receptor expression and in their susceptibility to death. These changes are observed not only in infected cells but also in bystan
• PMID 24248906

• Plasma B-type natriuretic peptide (BNP) in acute Puumala hantavirus infection.

• Rajaniemi SM, Hautala N, Sironen T, Vainio O, Vapalahti O, Vaheri A, Vuolteenaho O, Ruskoaho H, Kauma H, Hautala T.Author information Institute of Diagnostics, Department of Medical Microbiology, University of Oulu , Oulu , Finland.AbstractAbstract Background. Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome (HFRS) caused by Puumala hantavirus (PUUV). Acute infection causes transient kidney injury, permeability disorder, and fluid retention, for example. Methods. B-type natriuretic peptide (BNP) and N-terminal peptide (NT-proBNP) during NE were investigated; disease severity and development of clinical symptoms were considered. Results. Mean concentrations were 80.2 pg/mL and 55.2 pg/mL for BNP, and 2362.5 pg/mL and 1057.0 pg/mL for NT-proBNP in males and females, respectively. Hospitalization was 6.3 versus 5.2 days (P = 0.01) and 5.9 versus 4.4 days (P = 0.01) for patients with elevated BNP (> 100 pg/mL) or NT-proBNP (> 300 pg/mL), respectively, compared to those with normal peptide concentrations. Weight change during hospitalization was -2.8 or -0.3 kg (P <0.05) in patients with elevated or normal BNP, respectively. Heart rate (r = -0.46, P = 0.001 and r = -0.37, P = 0.01), creatinine clearance (r = -0.46, P = 0.001 and r = -0.56, P = 0.000), blood haemoglobin concentration (r = -0.55, P = 0.000 and r = -0.52, P = 0.000), and C-reactive protein (r = -0.47, P = 0.001 and r = -0.36, P = 0.01) measured when the peptide samples were collected correlated with BNP and NT-proBNP, respectively. In addition, anterior chamber depth of eye and plasma BNP (r = -0.39, P < 0.05) displayed a correlation. Conclusions. BNP and NT-proBNP levels are associated with severity of several clinical features of acute NE.
• Annals of medicine.Ann Med.2014 Feb;46(1):38-43. doi: 10.3109/07853890.2013.862960. Epub 2014 Jan 6.
• Abstract Background. Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome (HFRS) caused by Puumala hantavirus (PUUV). Acute infection causes transient kidney injury, permeability disorder, and fluid retention, for example. Methods. B-type natriuretic peptide (BNP) and N-terminal p
• PMID 24393073

Related Links

• Andes virus - definition of Andes virus by Medical dictionary

A serologically distinct member of the Hantavirus group found in 1995 in the Andes which may cause renal failure and hantavirus pulmonary syndrome; Andes virus infection carries a 30–50% mortality Andes virus (an'dēz), a species ...

• Andes_virus - bionity.com - Das Fachportal für Biotechnologie ...

Andes virus This article needs additional citations for verification.Please help improve this article by adding reliable references. Unsourced material may be ... my.bionity.com With an accout for my.bionity.com you can always see ...

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★リンクテーブル★

リンク元	「hantavirus」「アンデスウイルス」
関連記事	「virus」

「hantavirus」

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• ハンタウイルス

関

Andes virus、hantaviral

「アンデスウイルス」

　　[★]

英

Andes virus

関

ハンタウイルス

「virus」

　　[★] ウイルス