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English Journal

Hokkaido genotype of Puumala virus in the grey red-backed vole (Myodes rufocanus) and northern red-backed vole (Myodes rutilus) in Siberia.

Yashina LN1, Abramov SA2, Dupal TA2, Danchinova GA3, Malyshev BS4, Hay J5, Gu SH6, Yanagihara R7.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.Infect Genet Evol.2015 Jul;33:304-13. doi: 10.1016/j.meegid.2015.05.021. Epub 2015 May 21.
Three species of Myodes voles known to harbor hantaviruses include the bank vole (Myodes glareolus), which serves as the reservoir host of Puumala virus (PUUV), the prototype arvicolid rodent-borne hantavirus causing hemorrhagic fever with renal syndrome (HFRS) in Europe, and the grey red-backed vol
PMID 26003760

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion.

Kleinfelter LM1, Jangra RK1, Jae LT2, Herbert AS3, Mittler E1, Stiles KM4, Wirchnianski AS3, Kielian M4, Brummelkamp TR2, Dye JM5, Chandran K6.
mBio.MBio.2015 Jun 30;6(4). pii: e00801-15. doi: 10.1128/mBio.00801-15.
Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) in the Old World and a highly fatal hantavirus cardiopulmonary syndrome (HCPS) in the New World. No vaccines or antiviral therapies are currently available to prevent or treat hantavirus disease, and gaps in our understanding of how han
PMID 26126854

Construction and evaluation of DNA vaccine encoding Hantavirus glycoprotein N-terminal fused with lysosome-associated membrane protein.

Jiang DB1, Sun YJ2, Cheng LF3, Zhang GF1, Dong C4, Jin BQ2, Song CJ2, Ma Y2, Zhang FL5, Yang K6.
Vaccine.Vaccine.2015 Jun 26;33(29):3367-76. doi: 10.1016/j.vaccine.2015.05.007. Epub 2015 May 28.
BACKGROUND: Hantaviral diseases can have a high case fatality rate within the absence of broadly effective antiviral treatments or vaccines. We developed a DNA vaccine targeting the Hantavirus glycoprotein N-terminal (Gn) to major histocompatibility complex class II compartment by fusing the antigen
PMID 26027907

特別講演 Emergence and control of Hantaviral diseases〔含抄訳〕 (第45回日本感染症学会中日本地方会総会学術講演会後抄録)

Epizootiological survey of hantavirus among rodent species in Ningxia Hui Autonomous Province, China

KARIWA Hiroaki,CUI Bai Zhong,ARAKI Koichi,YOSHIMATSU Kumiko,LOKUGAMAGE Kumari,LOKUGAMAGE Nandadeva,MURPHY Michael E.,MIZUTANI Tetsuya,ARIKAWA Jiro,FUKUSHIMA Hiroshi,HU Xiong,CHEN Jiehua,TAKASHIMA Ikuo
Japanese Journal of Veterinary Research 49(2), 105-114, 2001-08-31
… Hantaviral antibodies were detected in the sera from Apodemus (A.) agrarius and A. … peninsulae were positive for hantaviral antibodies. … By WB, positive sera showed the same specific reaction pattern of baculovirus-expressed recombinant hantaviral nucleocapsid protein, as shown in hantavirus-immune serum. …
NAID 110001101457

Murphy Michael E.,苅和宏明,水谷哲也 [他],田辺寛樹,吉松組子,有川二郎,高島郁夫
The journal of veterinary medical science 63(6), 637-645, s・vi-s・vii, 2001-06-25
牛のラクトフェリン(LF)とリバビリン(Rbv)の抗ハンタウイルス活性の作用機序を解析した.ハンタウイルスのフォーカス形成はウイルス接種前に400μl/mlのLFを37℃で1時間処理すると,対照に比べ15%にまで低下した.ウイルス接種後に100μl/mlのRbvを作用するとフォーカス形成は対照の2.5%まで阻害された.LF前処理とRbv後処理の併用は完全にフォーカス形成を阻害した.ウイルスの糖蛋白 …
NAID 110003920667