同: アジソン病

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/08/17 21:40:21」(JST)

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1. 成人における副腎不全の臨床症状 clinical manifestations of adrenal insufficiency in adults
2. 成人における副腎不全の診断 diagnosis of adrenal insufficiency in adults
3. 成人における副腎不全の治療 treatment of adrenal insufficiency in adults
4. 原発性副腎不全（アジソン病）の原因 causes of primary adrenal insufficiency addisons disease
5. 小児における副腎不全の診断 diagnosis of adrenal insufficiency in children

English Journal

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.

Husebye ES, Allolio B, Arlt W, Badenhoop K, Bensing S, Betterle C, Falorni A, Gan EH, Hulting AL, Kasperlik-Zaluska A, Kämpe O, Løvås K, Meyer G, Pearce SH.Author information Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway.AbstractPrimary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex. Consequently, patients with PAI are at higher risk of developing other autoimmune diseases. The diagnosis of PAI is often delayed by many months, and most patients present with symptoms of acute adrenal insufficiency. Because PAI is rare, even medical specialists in this therapeutic area rarely manage more than a few patients. Currently, the procedures for diagnosis, treatment and follow-up of this rare disease vary greatly within Europe. The common autoimmune form of PAI is characterized by the presence of 21-hydroxylase autoantibodies; other causes should be sought if no autoantibodies are detected. Acute adrenal crisis is a life-threatening condition that requires immediate treatment. Standard replacement therapy consists of multiple daily doses of hydrocortisone or cortisone acetate combined with fludrocortisone. Annual follow-up by an endocrinologist is recommended with the focus on optimization of replacement therapy and detection of new autoimmune diseases. Patient education to enable self-adjustment of dosages of replacement therapy and crisis prevention is particularly important in this disease. The authors of this document have collaborated within an EU project (Euadrenal) to study the pathogenesis, describe the natural course and improve the treatment for Addison's disease. Based on a synthesis of this research, the available literature, and the views and experiences of the consortium's investigators and key experts, we now attempt to provide a European Expert Consensus Statement for diagnosis, treatment and follow-up.
Journal of internal medicine.J Intern Med.2014 Feb;275(2):104-15. doi: 10.1111/joim.12162. Epub 2013 Dec 16.
Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex. Consequently, patients with PAI are at higher risk of developing other autoimmune diseases. The diagnosis of
PMID 24330030

Gallbladder carcinoma: a New Zealand centre's 10-year experience with presentation, ethnic diversity and survival rate.

Lilic N, Addison B, Hammodat H.Author information Department of Otolaryngology Head and Neck Surgery, Middlemore Hospital, Auckland, New Zealand.AbstractBACKGROUND: Gallbladder cancer is a high-mortality cancer with a wide range of incidence worldwide. Some indigenous populations are known to have a higher incidence of gallbladder cancer. Commonly, it is incidentally discovered during routine gallbladder surgery. The primary aim was to determine the incidence and characteristics of gallbladder cancer in a New Zealand population. The secondary aim was to determine if inequalities in gallbladder cancer rates between Māori and non-Māori have decreased.
ANZ journal of surgery.ANZ J Surg.2014 Jan 20. doi: 10.1111/ans.12503. [Epub ahead of print]
BACKGROUND: Gallbladder cancer is a high-mortality cancer with a wide range of incidence worldwide. Some indigenous populations are known to have a higher incidence of gallbladder cancer. Commonly, it is incidentally discovered during routine gallbladder surgery. The primary aim was to determine the
PMID 24438645

Face-to-Face Handoff: Improving Transfer to the Pediatric Intensive Care Unit After Cardiac Surgery.

Vergales J, Addison N, Vendittelli A, Nicholson E, Carver DJ, Stemland C, Hoke T, Gangemi J.Author information 1University of Virginia Health System, Charlottesville, VA.AbstractThe goal was to develop and implement a comprehensive, primarily face-to-face handoff process that begins in the operating room and concludes at the bedside in the intensive care unit (ICU) for pediatric patients undergoing congenital heart surgery. Involving all stakeholders in the planning phase, the framework of the handoff system encompassed a combination of a formalized handoff tool, focused process steps that occurred prior to patient arrival in the ICU, and an emphasis on face-to-face communication at the conclusion of the handoff. The final process was evaluated by the use of observer checklists to examine quality metrics and timing for all patients admitted to the ICU following cardiac surgery. The process was found to improve how various providers view the efficiency of handoff, the ease of asking questions at each step, and the overall capability to improve patient care regardless of overall surgical complexity.
American journal of medical quality : the official journal of the American College of Medical Quality.Am J Med Qual.2014 Jan 17. [Epub ahead of print]
The goal was to develop and implement a comprehensive, primarily face-to-face handoff process that begins in the operating room and concludes at the bedside in the intensive care unit (ICU) for pediatric patients undergoing congenital heart surgery. Involving all stakeholders in the planning phase,
PMID 24443318