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Transarterial embolization with sorafenib in animal livers: a pharmacokinetics study.

Chatziioannou AN, Siskos AP, Loxas D, Kavatzas N, Agrogiannis G, Fokas D, Malagari K, Kostomitsopoulos NG, Tsigkou O, Tamvakopoulos C.Source1st and 2nd Departments of Radiology, University of Athens, Athens.
Journal of vascular and interventional radiology : JVIR.J Vasc Interv Radiol.2013 Nov;24(11):1657-1663.e1. doi: 10.1016/j.jvir.2013.08.007. Epub 2013 Sep 21.
PURPOSE: To assess the safety and feasibility of the targeted delivery of the antiangiogenic drug sorafenib to the liver using transarterial chemoembolization methodology as a novel approach to hepatocellular carcinoma (HCC) therapy.MATERIALS AND METHODS: Seven healthy New Zealand white rabbits were
PMID 24060438

Radical-mediated reduction of the dithiocarbamate group under tin-free conditions.

McMaster C, Bream RN, Grainger RS.SourceSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Organic & biomolecular chemistry.Org Biomol Chem.2012 Jun 28;10(24):4752-8. doi: 10.1039/c2ob25434d. Epub 2012 May 15.
Reductive desulfurisation of dithiocarbamates is conveniently achieved using H(3)PO(2)-Et(3)N-ACCN in refluxing dioxane. Fused and spirocyclic β-lactams, prepared through 4-exo trig carbamoyl radical cyclisation-dithiocarbamate group transfer reactions, are reduced without fragmentation of the stra
PMID 22588594

Garcia-Dominic O, Lengerich EJ, Wray LA, Parrott R, Aumiller B, Kluhsman B, Renderos C, Dignan M.SourceDepartment of Public Health Sciences, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA. odominic@hes.hmc.psu.edu
American journal of health behavior.Am J Health Behav.2012 Mar;36(2):153-67. doi: 10.5993/AJHB.36.2.2.
OBJECTIVES: To describe knowledge of and barriers to colorectal cancer (CRC) screening by sex and geography among Latino adults in Pennsylvania.METHODS: Eighty-two Latinos >50 years old engaged in one of 8 focus groups. Focus groups consisted of 4 components. Focus group data were audiotaped, tr
PMID 22370254

HONGO Toshio,HIKAGE Sakari,SATO Atsushige
Dental materials journal 25(2), 298-302, 2006-06
… BPO was dissolved in acetone, acetonitrile (AcCN), 50% acetonitrile-50% distilled water (50% AcCN), ethyl alcohol (EtOH), and methyl alcohol (MeOH). … In MeOH, BPO rapidly decomposed into benzoic acid (BA) and methyl benzoate (MeBA) time-dependently, whereas BPO in acetone, AcCN, and 50% AcCN was relatively stable. …
NAID 110004757982

Design and Synthesis of a Novel Water-Soluble NMDA Receptor Antagonist with a 1, 4, 7, 10-Tetraazacyclododecane Group

MASUKO Takashi,METORI Koichi,KIZAWA Yasuo,KUSAMA Tadashi,MIYAKE Muneharu
Chemical & pharmaceutical bulletin 53(4), 444-447, 2005-04-01
… Two types of water-soluble NMDA receptor antagonist, ACCn (1) and TGCn (2), with a 1, 4, 7, 10-tetraazacyclododecane cyclic polyamine group, were synthesized and the effects of both compounds on NMDA receptors were studied using voltage-clamp recordings of recombinant NMDA receptors expressed in Xenopus oocytes. … The inhibitory effects of ACCn (1) on both NMDA receptors were more potent than those of TGCn (2). …
NAID 10016653290