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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/25 17:11:43」(JST)
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In human genetics, the Atlantic Modal Haplotype (AMH) or haplotype 15 is a Y chromosome haplotype of Y-STR microsatellite variations, associated with the Haplogroup R1b. It was discovered prior to many of the SNPs now used to identify subclades of R1b and references to it can be found in some of the older literature. It corresponds most closely with subclade R1b1a2a1a(1) [L11].
The AMH is the most frequently occurring haplotype amongst human males in Atlantic Europe. It is characterized by the following marker alleles:
- DYS388 12
- DYS390 24
- DYS391 11
- DYS392 13
- DYS393 13
- DYS394 14 (also known as DYS19)
It reaches the highest frequencies in the Iberian Peninsula, in Great Britain and Ireland. In the Iberian Peninsula it reaches 70% in Portugal as a whole, more than 90% in NW Portugal and nearly 90% in Galicia (NW Spain), while the highest value is to be found among Spain and the Basques.
One mutation in either direction, would be AMH 1.15+. The AMH 1.15 set of haplotypes is also referred to as the Atlantic Modal Cluster or AMC.
See also
- Modal haplotype
- Haplotype
- Haplogroup
- Haplogroup R1b
- List of Y-STR markers
External links
- Some Haplotype Definitions
- Some Variations of DYS390
- A PNAS article on AMH and variations on the British Isles
English Journal
- Three two-component transporters with channel-like properties have monovalent cation/proton antiport activity.
- Fujisawa M1, Ito M, Krulwich TA.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2007 Aug 14;104(33):13289-94. Epub 2007 Aug 6.
- Properties of four two-component bacterial transport systems of the cation/proton antiporter-2 (CPA2) family led to suggestions that this CPA2 subset may use a channel rather than an antiport mechanism [see Booth IR, Edwards MD, Gunasekera B, Li C, Miller S (2005) in Bacterial Ion Channels, eds Kuba
- PMID 17679694
- Fifty years in medical informatics.
- Collen MF.
- Yearbook of medical informatics.Yearb Med Inform.2006:174-9.
- OBJECTIVES: An overview of personal experiences in medical informatics based on Dr. Morris Collen's 50 years of research in the field.METHODS: A personal reminiscence and historical overview, focusing on the first two decades of medical informatics, when Dr. Collen began working with Dr. Sidney Garf
- PMID 17051312
Japanese Journal
- Automated Computer Assisted Diagnosis of ECG and PCG in the Cardiovascular Screening System : PANEL DISCUSSION ON INFORMATION PROCESSING AND AUTOMATIC DIAGNOSIS OF CIRCULATORY SYSTEM
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