ACTINEX

English Journal

Nordihydroguiaretic acid attenuates skin tumorigenesis in Swiss albino mice with the condition of topical co-administration of an immunosuppressant.

Rahman S1, Farooque A2, Anjum S1, Ansari RA1, Adhikari JS2, Dwarakanath BS2, Raisuddin S3.
Chemico-biological interactions.Chem Biol Interact.2015 May 25;233:106-14. doi: 10.1016/j.cbi.2015.03.006. Epub 2015 Mar 11.
Drug and chemically-induced immunosuppression has been implicated as a confounding factor for cancer development. Management of cancer in such situation is often a challenging task. We tested the efficacy of nordihydroguiaretic acid (NDGA) against immunosuppressant tacrolimus-induced augmentation of
PMID 25770929

Pickering AM, Lehr M, Miller RA.
The Journal of clinical investigation.J Clin Invest.2015 May;125(5):2059-68. doi: 10.1172/JCI80514. Epub 2015 Apr 13.
There is large variation in lifespan among different species, and there is evidence that modulation of proteasome function may contribute to longevity determination. Comparative biology provides a powerful tool for identifying genes and pathways that control the rate of aging. Here, we evaluated ski
PMID 25866968

Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2.

Wang Z1, Wang B1, Shi Y1, Xu C1, Xiao HL1, Ma LN1, Xu SL1, Yang L1, Wang QL1, Dang WQ1, Cui W1, Yu SC1, Ping YF1, Cui YH1, Kung HF1, Qian C1, Zhang X1, Bian XW1.
Oncogene.Oncogene.2015 Mar 12;34(11):1407-19. doi: 10.1038/onc.2014.75. Epub 2014 Apr 7.
Emerging evidence has shown that cancer stem cells (CSCs) are the cellular determinants to promote cancer invasion and metastasis. However, the mechanism underlying CSC invasion remains unknown. MicroRNAs are evolutionally conserved small noncoding RNAs that are critical for the regulation of gene e
PMID 24704830