3
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 起立性低血圧および食後低血圧の治療 treatment of orthostatic and postprandial hypotension
- 2. 閉経期のホルモン療法：利益とリスク menopausal hormone therapy benefits and risks
English Journal
- The discovery of the pressor effect of DOPS and its blunting by decarboxylase inhibitors.
- Kaufmann H.SourceMount Sinai School of Medicine, New York, NY 10029, USA. Horacio.Kaufmann@mssm.edu
- Journal of neural transmission. Supplementum.J Neural Transm Suppl.2006;(70):477-84.
- In the 1950s it was found that an artificial aminoacid, 3,4-threo-dihydroxyphenylserine (DOPS), was converted to norepinephrine (NE) in a single step by the enzyme L-aromatic amino acid decarboxylase (AADC), bypassing the need for the rate limiting enzyme dopamine beta hydroxylase. Trying to replica
- PMID 17017570
- DL-3,4-threo-DOPS in Parkinson's disease: effects on orthostatic hypotension and dizziness.
- Birkmayer W, Birkmayer G, Lechner H, Riederer P.AbstractParkinsonian patients with orthostatic hypotension and dizziness due to usual antiparkinson therapy have been treated with the precursor amino-acid of noradrenaline, DL-3,4-threo-dihydroxyphenylserine (DL-3,4-threo-DOPS). Oral and intravenous administration improved these side effects significantly. A combined treatment of L-dopa, peripheral decarboxylase inhibitor and DL-3,4-threo-DOPS seems to be of benefit with respect to akinesia and orthostatic hypotension.
- Journal of neural transmission.J Neural Transm.1983;58(3-4):305-13.
- Parkinsonian patients with orthostatic hypotension and dizziness due to usual antiparkinson therapy have been treated with the precursor amino-acid of noradrenaline, DL-3,4-threo-dihydroxyphenylserine (DL-3,4-threo-DOPS). Oral and intravenous administration improved these side effects significantly.
- PMID 6420517
Related Links
- 1. Yamagami, S., et al., Suppression of hyperemia after brain ischemia by L-threo-3,4-dihydroxyphenylserine. Neuroreport 9, 2939-2943, (1998) 2. Thomas, S.A., et al., Restoration of norepinephrine and reversal of phenotypes in mice ...
- DL-threo-3,4-Dihydroxyphenylserine [customers have already purchased DL-threo-3,4-Dihydroxyphenylserine.] Share | Get Latest Price Company Profile Added to your Inquiry onlie Product name:DL-threo-3,4-Dihydroxyphenylserine ...
Related Pictures
★リンクテーブル★
| リンク元 | 「3,4-threo-DOPS」「3,4-スレオジヒドロキシフェニルセリン」「threo-DOPS」 |
「3,4-threo-DOPS」
3