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1. 皮膚筋炎および多発性筋炎における悪性腫瘍malignancy in dermatomyositis and polymyositis [show details]
…population . There is a strong association between ovarian cancer and the presence of the anti-transcription intermediary factor 1 (TIF1) antibody . Cancer can be diagnosed before, simultaneously with, or after …
2. 炎症性ミオパチーの病因pathogenesis of inflammatory myopathies [show details]
…subtypes associated with anti-melanoma differentiation-associated protein 5 (anti-MDA5), anti-transcription intermediary factor 1-gamma (anti-TIF1-gamma), anti-nuclear matrix protein 2 (anti-NXP2), and anti-small…
3. 脊髄、末梢神経、筋肉に影響を与える腫瘍随伴性症候群paraneoplastic syndromes affecting spinal cord peripheral nerve and muscle [show details]
…confer increased risk of cancer (eg, antibodies to nuclear matrix protein 2 [NXP-2] and transcription intermediary factor 1 gamma). The most common tumors are cancer of the breast, lung, ovary, and stomach…
4. 脂肪酸酸化障害の概要overview of fatty acid oxidation disorders [show details]
…of FAO enzyme gene transcription. Bezafibrate, used in the treatment of hyperlipidemia, is an agonist of peroxisome proliferator-activated receptor (PPAR) and promotes transcription of many genes encoding …
5. 遺伝学の基礎概念：DNA制御と遺伝子発現basic genetics concepts dna regulation and gene expression [show details]
…circumstances. Transcription occurs from the antisense DNA strand, in the 5' to 3' direction. Transcription requires that cellular machinery unfold the DNA to allow transcriptional regulators (transcription factors) …