英: targetand hit theory
関: LQモデル

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1. 心臓や血管の手術時のヘパリン起因性血小板減少症（HIT）のマネージメントmanagement of heparin induced thrombocytopenia hit during cardiac or vascular surgery [show details]
… an approach to the perioperative management of individuals with suspected HIT, a previous diagnosis of HIT, or known active HIT who require elective or emergency surgery that typically includes heparin …
2. ヘパリン起因性血小板減少症の臨床症状および診断clinical presentation and diagnosis of heparin induced thrombocytopenia [show details]
… between these two forms of HIT is made based on clinical parameters such as the timing and degree of platelet count drop, and laboratory testing if needed. HIT type I (HIT I) is a mild, transient drop …
3. ヘパリン起因性血小板減少症のマネージメントmanagement of heparin induced thrombocytopenia [show details]
… schedule, or route of administration. HIT results from an autoantibody directed against platelet factor 4 (PF4) in complex with heparin (referred to as a HIT antibody). HIT antibodies activate platelets and …
4. 静脈血栓症の原因の概要overview of the causes of venous thrombosis [show details]
… was HIT-associated. In this study, approximately one in every eight episodes of VTE occurring in UFH-treated patients was due to HIT. Accordingly, clinicians should suspect the possibility of HIT if VTE… A major theory delineating the pathogenesis of venous thromboembolism (VTE),…
5. 下肢深部静脈血栓症の治療の概要overview of the treatment of lower extremity deep vein thrombosis dvt [show details]
…therapy should be individualized . For patients with a DVT and a diagnosis of heparin-induced thrombocytopenia (HIT), all forms of heparin should be discontinued. This includes UFH, LMW heparin, heparin …