English Journal

Formosusin A, a novel specific inhibitor of mammalian DNA polymerase β from the fungus Paecilomyces formosus.

Mizushina Y1, Suzuki-Fukudome H2, Takeuchi T2, Takemoto K2, Kuriyama I3, Yoshida H3, Kamisuki S2, Sugawara F2.
Bioorganic & medicinal chemistry.Bioorg Med Chem.2014 Feb 1;22(3):1070-6. doi: 10.1016/j.bmc.2013.12.038. Epub 2013 Dec 25.
Variotin (1) and three novel compounds, formosusin A (2), B (3), and C (4), were isolated from the cultures of the fungus Paecilomyces formosus, and their structures were determined by spectroscopic analyses. Compound 2 is (6Z,8E,10E)-variotin, a new cis-olefin analog of compound 1. Compound 2 selec
PMID 24411199

[Influence of incubation time on metabolites in mycelia of Paecilomyces militaris].

Zhang D1, Li S, Lu R, Li K, Luo F, Peng F, Hu F.
Wei sheng wu xue bao = Acta microbiologica Sinica.Wei Sheng Wu Xue Bao.2012 Dec 4;52(12):1477-88.
OBJECTIVE: To determine the secondary metabolites production in mycelia of Paecilomyces militaris.METHODS: Mycelia were cultured in plates with sabouraud dextrose agar yeast medium at 25 degrees C for 9 days. Sampling was done every day from the second to the ninth day. The secondary metabolites in
PMID 23457797

[Therapeutic efficacy of a topical tolnaftate preparation in guinea pig model of tinea pedis].

Yamaguchi H1, Uchida K, Tanaka T, Yamaguchi T.
The Japanese journal of antibiotics.Jpn J Antibiot.2001 Jun;54(6):323-30.
The therapeutic efficacy of a topical antifungal ointment containing 2% tolnaftate was studied in a guinea pig model of tinea pedis using the following four topical antifungal preparations commercially available as reference drugs: variotin (3,000 U/g ointment); phenyl-11-iodo-10-undecynoate (0.5% o
PMID 11521512