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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/07 23:00:22」(JST)

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  • Tissue and urokinase plasminogen activators instigate the degeneration of retinal ganglion cells in a mouse model of glaucoma.
  • Chintala SK1.
  • Experimental eye research.Exp Eye Res.2016 Feb;143:17-27. doi: 10.1016/j.exer.2015.10.003. Epub 2015 Oct 22.
  • Elevated intraocular pressure (IOP) promotes the degeneration of retinal ganglion cells (RGCs) during the progression of Primary Open-Angle Glaucoma (POAG). However, the molecular mechanisms underpinning IOP-mediated degeneration of RGCs remain unclear. Therefore, by employing a mouse model of POAG,
  • PMID 26474495
  • Decreased expression of the plasminogen activator inhibitor type 1 is involved in degradation of extracellular matrix surrounding cervical cancer stem cells.
  • Sato M1, Kawana K1, Adachi K1, Fujimoto A1, Yoshida M1, Nakamura H1, Nishida H1, Inoue T1, Taguchi A1, Takahashi J1, Kojima S1, Yamashita A1, Tomio K1, Nagamatsu T1, Wada-Hiraike O1, Oda K1, Osuga Y1, Fujii T1.
  • International journal of oncology.Int J Oncol.2016 Feb;48(2):829-35. doi: 10.3892/ijo.2015.3283. Epub 2015 Dec 9.
  • The plasminogen activator (PA) system consists of plasminogen activator inhibitor type 1 (PAI-1), urokinase-type plasminogen activator and its receptor (uPA and uPAR). PAI-1 inhibits the activation of uPA (which converts plasminogen to plasmin), and is involved in cancer invasion and metastasis, by
  • PMID 26676222
  • Hypoxia inducible factor-1 mediates upregulation of urokinase-type plasminogen activator receptor gene transcription during hypoxia in cervical cancer cells.
  • Nishi H1, Sasaki T1, Nagamitsu Y1, Terauchi F1, Nagai T2, Nagao T2, Isaka K1.
  • Oncology reports.Oncol Rep.2016 Feb;35(2):992-8. doi: 10.3892/or.2015.4449. Epub 2015 Nov 25.
  • Hypoxia occurs during development of cervical cancer and is considered to correlate with its invasion. Hypoxia mediates tumor cells to have more invasive property in a variety of cancers. Urokinase plasminogen activator receptor (uPAR) which mediates invasion is considered to be induced by hypoxia.
  • PMID 26718775


  • 症例報告 Streptococcus intermediusとBacillus circulansを起炎菌とした膿胸に対しウロキナーゼによる胸腔内注入が有効であった1例
  • 藤原 清宏,大田 正秀,小林 真也 [他]
  • 救急医学 = The Japanese journal of acute medicine 39(8), 1006-1011, 2015-08
  • NAID 40020560255
  • 内視鏡下脊柱管拡大術におけるウロキナーゼ固定化抗血栓性ドレーンの効果とドレーン設置法の工夫 (日本脊椎・脊髄神経手術手技学会 特集号) -- (合併症)
  • 中村 周
  • Journal of spine research : official journal of the Japanese Society for Spine Surgery and Related Research 6(7), 1215-1219, 2015-07
  • NAID 40020546274
  • 急性期脳梗塞における,治療別に見た急性期血行再建術の成績の比較
  • 竹中 朋文,芝野 克彦,梅垣 昌士,佐々木 学,鶴薗 浩一郎,松本 勝美
  • 脳卒中 advpub(0), 2015
  • 要旨:急性期脳梗塞への治療は,血管内治療併用や閉塞血管別の治療方針など未確定な部分が多い.我々は2005 年4 月~2014 年10 月の間に急性期脳梗塞にてrt-PA 静注療法および血管内治療,あるいはその双方を施行した急性期脳梗塞患者191 例に対し,A 群(rt-PA 静注),B 群(ウロキナーゼ動注),C 群(機械的血栓除去),D 群(failed rt-PA 患者に血管内治療を追加)に分 …
  • NAID 130005101624


Urokinase Urokinase、 また呼ばれたurokinase タイプはPlasminogen 活性剤(uPA) である 酵素 (欧州共同体 a として使用されて thrombolytic 厳しくか大きいの処置の代理店 深い静脈の血栓症、 肺エンボリズム、 心筋梗塞 ...
urokinase / ˌyʊər əˈkaɪ neɪs, -neɪz / Show Spelled [y oo r-uh-kahy-neys, -neyz] Show IPA noun Biochemistry, Pharmacology. an enzyme, present in the blood and urine of mammals, that activates plasminogen and is used ...



リンク元ウロキナーゼ」「u-PA」「urinary plasminogen activator」「uPA
拡張検索urokinase-type plasminogen activator



英:urokinase, UK
尿型プラスミノゲン活性化酵素 urinary plasminogen activator uPA
PT. 264

  • 腎上皮細胞で形成され、尿中に排泄されるプラスミノゲン活性化因子



urinary plasminogen activatorurokinaseurokinase-type plasminogen activator

urinary plasminogen activator」



u-PAurokinaseurokinase-type plasminogen activator




urokinase-type plasminogen activator」


u-PAurinary plasminogen activatorurokinase