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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/24 01:12:58」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/03/14 00:33:54」(JST)

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  • USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration.
  • Huang Z1, Wen P, Kong R, Cheng H, Zhang B, Quan C, Bian Z, Chen M, Zhang Z, Chen X, Du X, Liu J, Zhu L, Fushimi K, Hua D, Wu JY.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2015 Apr 15;136(8):1792-802. doi: 10.1002/ijc.29226. Epub 2014 Sep 29.
  • Originally discovered in neuronal guidance, the Slit-Robo pathway is emerging as an important player in human cancers. However, its involvement and mechanism in colorectal cancer (CRC) remains to be elucidated. Here, we report that Slit2 expression is reduced in CRC tissues compared with adjacent no
  • PMID 25242263
  • Andrographolide decreased VEGFD expression in hepatoma cancer cells by inducing ubiquitin/proteasome-mediated cFos protein degradation.
  • Ji L1, Zheng Z2, Shi L2, Huang Y2, Lu B2, Wang Z3.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2015 Apr;1850(4):750-8. doi: 10.1016/j.bbagen.2015.01.005. Epub 2015 Jan 14.
  • BACKGROUND: Andrographolide (Andro) is reported to inhibit hepatoma tumor growth in our previous studies. This study aims to further search the critical signals involved in such Andro-induced inhibition.METHODS: The anti-tumor effect of Andro was evaluated in vivo. Cancer PathwayFinder RT(2) Profile
  • PMID 25596551
  • Heterogeneous expression and biological function of ubiquitin carboxy-terminal hydrolase-L1 in osteosarcoma.
  • Zheng S1, Qiao G1, Min D1, Zhang Z2, Lin F1, Yang Q2, Feng T1, Tang L1, Sun Y1, Zhao H1, Li H1, Yu W1, Yang Y1, Shen Z3, Yao Y3.
  • Cancer letters.Cancer Lett.2015 Apr 1;359(1):36-46. doi: 10.1016/j.canlet.2014.12.001. Epub 2015 Jan 8.
  • Ubiquitin carboxyl terminal hydrolase 1 (UCHL1), a member of the UCH class of DUBs, has been reported as either an oncogene or a tumor suppressor. However, the molecular mechanism underlying the biological function of UCHL1 in osteosarcoma is still unclear. This study was aimed at elucidating the ro
  • PMID 25578779


  • NPM1変異陽性急性骨髄性白血病に対するATRAおよびATOの有効性
  • KIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition
  • Dietary Supplementation with Isoflavones Prevents Muscle Wasting in Tumor-Bearing Mice
  • Journal of nutritional science and vitaminology 62(3), 178-184, 2016-06
  • NAID 40020863779


Ubiquitin definition, a small protein, present in all eukaryotic cells, that participates in the destruction of defective proteins and in the synthesis of new proteins. See more. Dictionary.com Word of the Day Translate Games Blog ...
Ubiquitin is a small protein that is found in almost all cellular tissues in humans and other eukaryotic organisms, which helps to regulate the processes of other proteins in the body.



リンク元ubiquitin-like protein
拡張検索ubiquitin ligase」「small ubiquitin-related modifier」「ubiquitin-mediated proteolysis」「ubiquitin-conjugating enzyme

ubiquitin-like protein」



ubiquitin ligase」



ubiquitin-protein ligase

small ubiquitin-related modifier」


small ubiquitin-like modifierSUMO

ubiquitin-mediated proteolysis」


ubiquitin-dependent proteolysis

ubiquitin-conjugating enzyme」



ubiquitin-conjugating enzyme E2