- 腫瘍抑制遺伝子産物、(日本語ではこのほうが多い)癌抑制遺伝子産物
WordNet
- a chemical substance formed as a result of a chemical reaction; "a product of lime and nitric acid"
- a consequence of someones efforts or of a particular set of circumstances; "skill is the product of hours of practice"; "his reaction was the product of hunger and fatigue"
- an artifact that has been created by someone or some process; "they improve their product every year"; "they export most of their agricultural production" (同)production
- a quantity obtained by multiplication; "the product of 2 and 3 is 6" (同)mathematical product
- to put down by force or authority; "suppress a nascent uprising"; "stamp down on littering"; "conquer ones desires" (同)stamp down, inhibit, subdue, conquer, curb
- reduce the incidence or severity of or stop; "suppress a yawn"; "this drug can suppress the hemorrhage"
- put out of ones consciousness (同)repress
- an electrical device for suppressing unwanted currents (同)suppresser
- someone who suppresses; "dictators are suppressors of free speech" (同)suppresser
- a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene) (同)suppresser, suppressor_gene, suppresser gene
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
- an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm
PrepTutorEJDIC
- 『産物』;製品 / (…の)結果,帰結《+『of』+『名』(do『ing』)》 / (数の)積 / (化学の)生成物
- 〈反乱など〉‘を'『鎮圧する』…,‘の'活動を押える / 〈感情・欲望など〉‘を'『抑制する』,抑える / …‘の'発表を禁止する,伏せる
- 抑圧する人,鎮圧者 / (ラジオ・テレビの)妨害電波(混信)防止装置
- 遺伝子
UpToDate Contents
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- 1. 甲状腺結節および非髄様甲状腺癌におけるオンコジーンおよび腫瘍抑制遺伝子oncogenes and tumor suppressor genes in thyroid nodules and nonmedullary thyroid cancer [show details]
- 2. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化head and neck squamous cell carcinogenesis molecular and genetic alterations [show details]
- 3. 前立腺癌の分子生物学molecular biology of prostate cancer [show details]
- 4. 軟部および骨肉腫の病原因子pathogenetic factors in soft tissue and bone sarcomas [show details]
- 5. 大腸癌の分子遺伝学molecular genetics of colorectal cancer [show details]
English Journal
- Rapid Detection Method for the Four Most Common CHEK2 Mutations Based on Melting Profile Analysis.
- Borun P1, Salanowski K1, Godlewski D2, Walkowiak J3, Plawski A4,5.
- Molecular diagnosis & therapy.Mol Diagn Ther.2015 Oct 7. [Epub ahead of print]
- INTRODUCTION: CHEK2 is a tumor suppressor gene, and the mutations affecting the functionality of the protein product increase cancer risk in various organs. The elevated risk, in a significant percentage of cases, is determined by the occurrence of one of the four most common mutations in the CHEK2
- PMID 26446916
- HAND2‑mediated proteolysis negatively regulates the function of estrogen receptor α.
- Fukuda T1, Shirane A1, Wada-Hiraike O1, Oda K1, Tanikawa M1, Sakuabashi A1, Hirano M1, Fu H1, Morita Y1, Miyamoto Y1, Inaba K1, Kawana K1, Osuga Y1, Fujii T1.
- Molecular medicine reports.Mol Med Rep.2015 Oct;12(4):5538-44. doi: 10.3892/mmr.2015.4070. Epub 2015 Jul 9.
- A previous study demonstrated that the progesterone‑inducible HAND2 gene product is a basic helix‑loop‑helix transcription factor and prevents mitogenic effects of estrogen receptor α (ERα) by inhibiting fibroblast growth factor signalling in mouse uteri. However, whether HAND2 directly affe
- PMID 26166202
- ATM-dependent phosphorylation of the Fanconi anemia protein PALB2 promotes the DNA Damage Response.
- Guo Y1, Feng W1, Sy SM1, Huen MS2.
- The Journal of biological chemistry.J Biol Chem.2015 Sep 29. pii: jbc.M115.672626. [Epub ahead of print]
- The Fanconi anemia protein PALB2, also known as FANCN, protects genome integrity by regulating DNA repair and cell cycle checkpoints. Exactly how PALB2 functions may be temporally coupled with detection and signaling of DNA damage is not known. Intriguingly, we found that PALB2 is transformed into a
- PMID 26420486
Japanese Journal
- Cloning and expression analysis of prohibitin mRNA in canine mammary tumors
- MATSUYAMA Satoshi,NAKANO Yuko,NAKAMURA Mieko,YAMAMOTO Ryohei,SHIMADA Terumasa,OHASHI Fumihito,KUBO Kihei
- Journal of Veterinary Medical Science 77(1), 101-104, 2015
- … Prohibitin is an antiproliferative protein that is a product of a putative tumor suppressor gene. … Canine prohibitin mRNA was expressed in all normal mammary and tumor samples examined. …
- NAID 130004781004
- Cloning and expression analysis of prohibitin mRNA in canine mammary tumors
- MATSUYAMA Satoshi,NAKANO Yuko,NAKAMURA Mieko,YAMAMOTO Ryohei,SHIMADA Terumasa,OHASHI Fumihito,KUBO Kihei
- Journal of Veterinary Medical Science, 2014
- … Prohibitin is an antiproliferative protein that is a product of a putative tumor suppressor gene. … Canine prohibitin mRNA was expressed in all normal mammary and tumor samples examined. …
- NAID 130004693919
- ATMを介してRBタンパク質はDNMT1タンパク質の安定性とDNAメチル化を制御する
- Shamma Awad,Suzuki Misa,Hayashi Naoyuki,Kobayashi Masahiko,Sasaki Nobunari,Nishiuchi Takumi,Doki Yuichiro,Okamoto Takahiro,Kohno Susumu,Muranaka Hayato,Kitajima Shunsuke,Yamamoto Ken-ichi,Takahashi Chiaki
- Molecular biology of the cell 33(16), 3113-3124, 2013-08
- … The retinoblastoma tumor suppressor gene (RB) product has been implicated in epigenetic control of gene expression owing to its ability to physically bind to many chromatin modifiers. … To address this, we performed genetic and epigenetic analyses in an Rb-deficient mouse thyroid C cell tumor model. …
- NAID 120005312327
Related Pictures
★リンクテーブル★
| リンク元 | 「癌抑制遺伝子産物」「腫瘍抑制遺伝子産物」 |
| 関連記事 | 「product」「suppress」「suppressor」「tumor suppressor」「gene product」 |
「癌抑制遺伝子産物」
「腫瘍抑制遺伝子産物」
「product」
- n.
「suppress」
- v.
- 抑制する、抑える、抑止する
- 関
- abrogate、abrogation、arrest、curb、depress、depression、inhibit、inhibition、restrain、restraint、subdue、suppression
「suppressor」
「tumor suppressor」
「gene product」
- 遺伝子産物、・訳産物