WordNet

(medicine) an immunological response that refuses to accept substances or organisms that are recognized as foreign; "rejection of the transplanted liver"
the state of being rejected
the act of rejecting something; "his proposals were met with rejection"
the speech act of rejecting
any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

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1. 肝移植：急性細胞性拒絶反応の診断 liver transplantation diagnosis of acute cellular rejection
2. 造血細胞移植後の移植片対腫瘍効果の生物学 biology of the graft versus tumor effect following hematopoietic cell transplantation
3. 虫垂癌および腹膜偽粘液腫 cancer of the appendix and pseudomyxoma peritonei
4. 移植免疫 transplantation immunobiology
5. 小腸腫瘍の診断および病期分類 diagnosis and staging of small bowel neoplasms

UV irradiation of immunized mice induces type 1 regulatory T cells that suppress tumor antigen specific cytotoxic T lymphocyte responses.

Toda M, Wang L, Ogura S, Torii M, Kurachi M, Kakimi K, Nishikawa H, Matsushima K, Shiku H, Kuribayashi K, Kato T.SourceDepartment of Cellular and Molecular Immunology, Mie Graduate School of Medicine, Tsu, Japan.
International journal of cancer. Journal international du cancer.Int J Cancer.2011 Sep 1;129(5):1126-36. doi: 10.1002/ijc.25775. Epub 2011 Jan 12.
We previously showed that exposure to UV radiation after immunization suppresses Th1 and Th2 immune responses, leading to impaired Ab and allo-immune responses, but the impact of UV radiation after immunization on anti-tumor immune responses mediated by tumor-specific CD8(+) T cell responses remains
PMID 21710495

The ICOS/ICOSL Pathway Is Required for Optimal Antitumor Responses Mediated by Anti-CTLA-4 Therapy.

Fu T, He Q, Sharma P.SourceAuthors' Affiliations: Departments of Genitourinary Medical Oncology and Immunology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.
Cancer research.Cancer Res.2011 Aug 2. [Epub ahead of print]
The anti-CTL-associated antigen 4 (anti-CTLA-4) antibody ipilimumab is the first agent to show improved survival in a randomized phase III trial that enrolled patients with metastatic melanoma. Studies are ongoing to identify mechanisms that elicit clinical benefit in the setting of anti-CTLA-4 ther
PMID 21708958

木庭幸子
Skin Cancer 24(2), 159-163, 2009
生体内での腫瘍拒絶の主たるエフェクターはCD8陽性T細胞であり，その分子認識機構を利用して，腫瘍抗原を標的とした免疫療法が行われてきた。しかしながら，抗原刺激によって特異的T細胞の誘導が確認できても，臨床的に明らかな腫瘍拒絶にいたる例は少なく奏功率は低迷している。かねてから，腫瘍の免疫回避機構として，腫瘍や間質による抑制的サイトカイン産生，アポトーシス誘導，抗原の発現低下/消失，MHCの発現低下な …
NAID 130000909843