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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/10/16 20:32:35」(JST)

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  • Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas.
  • Zappasodi R1, Cavanè A, Iorio MV, Tortoreto M, Guarnotta C, Ruggiero G, Piovan C, Magni M, Zaffaroni N, Tagliabue E, Croce CM, Zunino F, Gianni AM, Di Nicola M.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2014 Nov 1;135(9):2034-45. doi: 10.1002/ijc.28852. Epub 2014 Mar 26.
  • Histone deacetylases (HDAC) extensively contribute to the c-Myc oncogenic program, pointing to their inhibition as an effective strategy against c-Myc-overexpressing cancers. We, thus, studied the therapeutic activity of the new-generation pan-HDAC inhibitor ITF2357 (Givinostat®) against c-Myc-over
  • PMID 24648290
  • Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogen.
  • Robinson KM1, Dunning Hotopp JC2.
  • Cancer letters.Cancer Lett.2014 Oct 1;352(2):137-44. doi: 10.1016/j.canlet.2014.05.021. Epub 2014 Jun 21.
  • Insertional mutagenesis has been repeatedly demonstrated in cancer genomes and has a role in oncogenesis. Mobile genetic elements can induce cancer development by random insertion into cancer related genes or by inducing translocations. L1s are typically implicated in cancers of an epithelial cell o
  • PMID 24956175
  • Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin.
  • Weinreb I1, Zhang L, Tirunagari LM, Sung YS, Chen CL, Perez-Ordonez B, Clarke BA, Skalova A, Chiosea SI, Seethala RR, Waggott D, Boutros PC, How C, Liu FF, Irish JC, Goldstein DP, Gilbert R, Ud Din N, Assaad A, Hornick JL, Thompson LD, Antonescu CR.
  • Genes, chromosomes & cancer.Genes Chromosomes Cancer.2014 Oct;53(10):845-56. doi: 10.1002/gcc.22195. Epub 2014 Jun 18.
  • Polymorphous low-grade adenocarcinoma (PLGA) and cribriform adenocarcinoma of minor salivary gland (CAMSG) are low-grade carcinomas arising most often in oral cavity and oropharynx, respectively. Controversy exists as to whether these tumors represent separate entities or variants of one spectrum, a
  • PMID 24942367


  • Phytofiltration of arsenic and cadmium by using an aquatic plant, Micranthemum umbrosum: Phytotoxicity, uptake kinetics, and mechanism
  • Islam Md. Shariful,Saito Takeshi,Kurasaki Masaaki
  • Ecotoxicology and Environmental Safety 112, 193-200, 2015-02
  • … Plant and water samples were analyzed for assessing the As and Cd accumulations, translocations, phytotoxic effects, uptake mechanisms and kinetics, and for evaluating the potential of M. …
  • NAID 120005517729
  • 急性リンパ性白血病の分子機構
  • 玉井 勇人,猪口 孝一
  • 臨床血液 56(3), 253-260, 2015
  • 急性リンパ性白血病(ALL)は成人がんも含め,過去30年間にもっとも予後が改善した悪性腫瘍のひとつである。ALLにおいてはこれまで形態学を中心とした病態解析の研究が進んできたが,近年のゲノム解析技術の進歩により,詳細な分子病態の解析や分類がなされるようになってきた。この項では急性リンパ性白血病の分子機構について解説した。小児急性リンパ性白血病acute lymphoblastic leukemia …
  • NAID 130005065343
  • Secondary EML4–ALK-positive Lung Adenocarcinoma in a Patient Previously Treated for Acute Lymphoblastic Leukemia in Childhood: A Case Reportated for Acute Lymphoblastic Leukemia in Childhood: A Case Report
  • Nakamura Yoichi,Taniguchi Hirokazu,Mizoguchi Kosuke,Ikeda Takaya,Motoshima Kohei,Yamaguchi Hiroyuki,Nagashima Seiji,Nakatomi Katsumi,Soda Manabu,Mano Hiroyuki,Kohno Shigeru
  • Japanese Journal of Clinical Oncology 44(6), 593-596, 2014-06
  • … These are mainly hematological malignancies, and recurrent chromosome translocations are commonly detected in such cases. … On the other hand, while secondary epithelial malignancies have sometimes been reported, chromosome translocations in these epithelial malignancies have not. …
  • NAID 120005457083


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Genetically, markers on nonhomologous chromosomes appear to be linked if these chromosomes take part in a translocation and the loci are close to the translocation breakpoint. Figure 17-25 shows a situation in which a translocation heterozygote ...



拡張検索AMLs with recurrent cytogenetic translocations」「Robertsonian translocations

AMLs with recurrent cytogenetic translocations」



Robertsonian translocations」

  [★] ロバートソン転座



  • n.

WordNet   license wordnet

「(genetics) an exchange of chromosome parts; "translocations can result in serious congenital disorders"」

WordNet   license wordnet

「the transport of dissolved material within a plant」