teniposide

出典: meddic

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VM-26

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/24 12:54:14」(JST)

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英文文献

  • Separating chemotherapy-related developmental neurotoxicity from cytotoxicity in monolayer and neurosphere cultures of human fetal brain cells.
  • Ivanov DP1, Al-Rubai AJ2, Grabowska AM3, Pratten MK4.
  • Toxicology in vitro : an international journal published in association with BIBRA.Toxicol In Vitro.2016 Dec;37:88-96. doi: 10.1016/j.tiv.2016.09.007. Epub 2016 Sep 10.
  • Chemotherapy-induced neurotoxicity can reduce the quality of life of patients by affecting their intelligence, senses and mobility. Ten percent of safety-related late-stage clinical failures are due to neurological side effects. Animal models are poor in predicting human neurotoxicity due to intersp
  • PMID 27622579
  • Preparation and evaluation of teniposide-loaded polymeric micelles for breast cancer therapy.
  • Chu B1, Shi S2, Li X2, Hu L3, Shi L3, Zhang H3, Xu Q3, Ye L3, Lin G3, Zhang N3, Zhang X4.
  • International journal of pharmaceutics.Int J Pharm.2016 Nov 20;513(1-2):118-129. doi: 10.1016/j.ijpharm.2016.09.005. Epub 2016 Sep 3.
  • Self-assembled polymeric micelles have been widely applied in anticancer drug delivery systems. Teniposide is a broad spectrum and effective anticancer drug, but its poor water-solubility and adverse effects of commercial formulation (VM-26) restrict its clinical application. In this work, teniposid
  • PMID 27596115
  • Biotechnological interventions for harnessing podophyllotoxin from plant and fungal species: current status, challenges, and opportunities for its commercialization.
  • Kumari A1,2, Singh D1, Kumar S1,2.
  • Critical reviews in biotechnology.Crit Rev Biotechnol.2016 Sep 20:1-15. [Epub ahead of print]
  • Podophyllotoxin is an aryltetralin lignan synthesized in several plant species, which is used in chemotherapies for cancers and tumor treatment. More potent semisynthetic derivatives of podophyllotoxin such as etoposide and teniposide are being developed and evaluated for their efficacy. To meet the
  • PMID 27644897

和文文献

  • Improved high-performance liquid chromatographic analysis of teniposide in human plasma
  • Journal of chromatography. B, Biomedical sciences and applications 709(2), 315-319, 1998-05-29
  • NAID 10024528775
  • Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132 : involvement of NF-κB activation in drug resistance
  • Randomized study of paclitaxel-cisplatin versus cisplatin-teniposide in patients with advanced non-small-cell lung cancer

関連リンク

Read more about the pharmacogenomics of teniposide on PharmGKB. ... Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they ...
Teniposide is a cancer medication that interferes with the growth and spread of cancer cells in the body. Teniposide is used to treat acute lymphoblastic leukemia (a type of blood cancer) in children. Teniposide is usually given after ...

関連画像

Téniposide (epidophyllotoxine)Teniposide (CAS 29767-20-2)Teniposide - Wikipedia, the free VUMON® (teniposide) Structural Formula File:Teniposide.svg - Wikimedia Commons220px-Teniposide.png


★リンクテーブル★
リンク元イリノテカン」「VM-26」「vumon

イリノテカン」

  [★]

irinotecan IRT, CPT-11
7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin]
塩酸イリノテカン irinotecan hydrochlorideイリノテカン塩酸塩
カンプトトポテシン
抗悪性腫瘍薬
抗腫瘍性植物成分製剤


概念

作用機序

  • トポイソメラーゼの機能を阻害してDNA合成を阻害する

block topoisomerase function

同じグループの薬剤


VM-26」

  [★]

tenoposide
teniposide
Teniposide
Teniposide


vumon」

  [★]

tenoposide
teniposide




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