出典: meddic


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「the univalent anion O2-; "much of the O2 supporting cellular respiration is reduced to the superoxide anion O2-"」
superoxide anion

WordNet   license wordnet

「a metallic oxide containing the univalent anion O2-」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/14 19:51:33」(JST)

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  • High pressure homogenization increases antioxidant capacity and short-chain fatty acid yield of polysaccharide from seeds of Plantago asiatica L.
  • Hu JL, Nie SP, Xie MY.SourceState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
  • Food chemistry.Food Chem.2013 Jun 15;138(4):2338-45. doi: 10.1016/j.foodchem.2012.12.016. Epub 2012 Dec 26.
  • Physiological properties of homogenized and non-homogenized polysaccharide from the seeds of Plantago asiatica L., including antioxidant capacity and short-chain fatty acid (SCFA) production, were compared in this study. High pressure homogenization decreased particle size of the polysaccharide, and
  • PMID 23497894
  • Valuable compounds in macroalgae extracts.
  • Andrade PB, Barbosa M, Matos RP, Lopes G, Vinholes J, Mouga T, Valentão P.SourceREQUIMTE/Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira No 228, 4050-313 Porto, Portugal.
  • Food chemistry.Food Chem.2013 Jun 1;138(2-3):1819-28. doi: 10.1016/j.foodchem.2012.11.081. Epub 2012 Nov 28.
  • Bioactive compounds present in ethanolic extracts from 18 macroalgae of the Portuguese coast were analysed by gas chromatography-mass spectrometry (GC-MS), leading to the characterization of 14 compounds: proline, phloroglucinol, mannitol, 8 fatty acids and 3 sterols. A dose-dependent response again
  • PMID 23411314
  • Purification and characterisation of a novel antioxidant peptide derived from blue mussel (Mytilus edulis) protein hydrolysate.
  • Wang B, Li L, Chi CF, Ma JH, Luo HY, Xu YF.SourceSchool of Food and Pharmacy, Zhejiang Ocean University, Qixiangtai Road 51, Zhoushan 316004, PR China. Electronic address:
  • Food chemistry.Food Chem.2013 Jun 1;138(2-3):1713-9. doi: 10.1016/j.foodchem.2012.12.002. Epub 2012 Dec 8.
  • Protein derived from blue mussel (Mytilus edulis) was hydrolysed using four kinds of proteases (pepsin, papain, neutrase and alcalase), and the neutrase hydrolysate (BNH) obtained by 3-h hydrolysis exhibited the highest 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity compared to oth
  • PMID 23411302
  • In vitro studies on α-glucosidase inhibition, antioxidant and free radical scavenging activities of Hedyotis biflora L.
  • Nimal Christhudas IV, Praveen Kumar P, Sunil C, Vajravijayan S, Lakshmi Sundaram R, Jenifer Siril S, Agastian P.SourceDepartment of Plant Biology and Biotechnology, Loyola College, Chennai 600 034, India.
  • Food chemistry.Food Chem.2013 Jun 1;138(2-3):1689-95. doi: 10.1016/j.foodchem.2012.11.051. Epub 2012 Nov 20.
  • Aim of this study was to evaluate the in vitro α-glucosidase inhibition and antioxidant activity of hexane, ethyl acetate and methanol extracts of Hedyotis biflora L. (Rubiaceae). In in vitro α-glucosidase inhibition and antioxidant activity, the methanol extract showed potent effect compared to h
  • PMID 23411299


  • A marine phytoplankton (Prymnesium parvum) up-regulates ABC transporters and several other proteins to acclimatize with Fe-limitation
  • Rahman M. Mamunur,Rahman M. Azizur,Maki Teruya,Nishiuchi Takumi,Asano T.,Hasegawa Hiroshi
  • Chemosphere (95), 213-219, 2014-01-01
  • … parvum increases the synthesis of ribulose biphosphate carboxylase (RuBisCo), malate dehydrogenase, and two Fe-independent oxidative stress response proteins, manganese superoxide dismutase (MnSOD) and Serine threonine kinase (STK). …
  • NAID 120005350316
  • Effects of Atorvastatin, Amlodipine, and Their Combination on Vascular Dysfunction in Insulin-Resistant Rats
  • Okamura Tomio,Tawa Masashi,Geddawy Ayman,Shimosato Takashi,Iwasaki Hirotaka,Shintaku Haruo,Yoshida Yuichi,Masada Masahiro,Shinozaki Kazuya,Imamura Takeshi
  • Journal of Pharmacological Sciences, 2014
  • … Deficiency of tetrahydrobiopterin (BH4) in the vascular tissue contributes to endothelial dysfunction through reduced eNOS activity and increased superoxide anion (O2−) generation in the insulin-resistant state. …
  • NAID 130003382630
  • レシチン化スーパーオキシドジスムターゼ(PC-SOD)の特発性肺線維症治療薬としての開発
  • 水島 徹
  • YAKUGAKU ZASSHI 134(1), 69-76, 2014
  • …   Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) are thought to involve lung injury induced by reactive oxygen species (ROS), in particular superoxide anion. … The enzyme, superoxide dismutase (SOD) catalyses the dismutation of superoxide anion to hydrogen peroxide. …
  • NAID 130003382312
  • Effects of Systemic Chlorogenic Acid on Random-Pattern Dorsal Skin Flap Survival in Diabetic Rats
  • Bagdas Deniz,Cam Etoz Betul,Inan Ozturkoglu Sevda,Cinkilic Nilufer,Ozyigit Musa Ozgur,Gul Zulfiye,Isbil Buyukcoskun Naciye,Ozluk Kasim,Gurun Mine Sibel
  • Biological and Pharmaceutical Bulletin, 2014
  • … The malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD) and nitric oxide (NO) levels were evaluated from the flap tissue. …
  • NAID 130003382132


Lewis electron configuration of superoxide. The six outer-shell electrons of each oxygen atom are shown in black; one electron pair is shared (middle); the unpaired electron is shown in the upper-left; and the additional electron ...
superoxide [soo″per-ok´sīd] any compound containing the highly reactive superoxide ion O 2 −, a common intermediate in numerous biological oxidations. su·per·ox·ide (sū'pĕr-oks'īd), An oxygen free radical, O 2-, which is toxic to ...
Superoxide definition, a compound containing the univalent ion O 2 − . See more. Thesaurus Translate Puzzles & Games Word of the Day Blog Slideshows Apps by Dictionary My Account Log Out Log In follow ...


SuperoxideDescription Superoxide.svgSuperoxides (Superoxide Radical)superoxideSuperoxide anion. Image source: Wikipedia  for Superoxide Dismutase | Sigma-AldrichImage:superoxide(-).PNGSuperoxides; Superoxide Radical

拡張検索manganese superoxide dismutase」「Cu-Zn superoxide dismutase」「copper-zinc superoxide dismutase」「superoxide anion free radical



azurophilic granule


  • アズールによって赤紫色に染色される細胞質内の顆粒で、血液細胞(顆粒球、単球、リンパ球)にみられる。顆粒球において顕著で、前骨髄球段階から出現
  • アズール好性
  • アズール→紫褐、紫赤
  • リンパ球、単球、前骨髄球、血小板、巨核球
  • リンパ球では0.3-0.6μm


NADPH + O2 -(NADPH oxidase)→ O2-・ (superoxide)
O2-・ -(spontaneous dismutation)→ H2O2 (gydrogen peroxide)
H2O2 -(myeloperoxidase)→ HOCl



スーパーオキシドラジカル superoxide radicalスーパーオキシドアニオン superoxide anion活性酸素
[show details]



obligate anaerobe, obligate anaerobes

  • first aid step1 2006 p.137
  • Clostridium, Bacteroides, and Actinomyces.
catalase and/or superoxideを欠く
  • アミノグリコシド系抗菌薬は無効。微生物の細胞内に薬剤が入るためにO2が必要だから

manganese superoxide dismutase」



Cu-Zn superoxide dismutaseMn-SODMnSODsuperoxide dismutase

Cu-Zn superoxide dismutase」



copper-zinc superoxide dismutasemanganese superoxide dismutaseMn-SODsuperoxide dismutase

copper-zinc superoxide dismutase」



Cu-Zn superoxide dismutase

superoxide anion free radical」


See also Free radicals