strychnine-induced seizures

出典: meddic

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  • Anticonvulsant action of indazole.
  • Matsumura N, Kikuchi-Utsumi K, Sakamaki K, Watabe M, Aoyama K, Nakaki T.SourceDepartment of Pharmacology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
  • Epilepsy research.Epilepsy Res.2012 Dec 5. pii: S0920-1211(12)00324-5. doi: 10.1016/j.eplepsyres.2012.11.001. [Epub ahead of print]
  • Here we report that indazole is characterized as a potential anticonvulsant, inhibiting pentylenetetrazole-, electroshock- and strychnine-induced convulsions in mice (ED(50)'s: 39.9, 43.2 and 82.4mg/kg, respectively) but not bicuculline- and picrotoxin-induced convulsions. The median toxic dose (TD(
  • PMID 23219048
  • Anticonvulsant action of Calotropis procera latex proteins.
  • Lima RC, Silva MC, Aguiar CC, Chaves EM, Dias KC, Macêdo DS, de Sousa FC, Carvalho Kde M, Ramos MV, Vasconcelos SM.SourceInstituto Superior de Biomedicina. Universidade Estadual do Ceará, Ceará, Brazil.
  • Epilepsy & behavior : E&B.Epilepsy Behav.2012 Feb;23(2):123-6. doi: 10.1016/j.yebeh.2011.11.008. Epub 2012 Jan 9.
  • Calotropis procera (Ait.) R.Br. is a laticiferous plant belonging to the Apocynaceae family. C. procera latex proteins were evaluated with respect to anticonvulsant and sedative activity in mouse models of pentylenetetrazol (PTZ)-, pilocarpine-, and strychnine-induced convulsions or turning behavior
  • PMID 22227595


  • L-NAME inhibits pentylenetetrazole and strychnine-induced seizures in mice
  • Strychnine-induced seizures in mice: the role of noradrenaline
  • Comparative study of tiapride and neuroleptics with anti-dopamine activity on convulsive seizure in mice.


The Journal of Neuroscience, October 1988, 8(10): 3822-3828 Glycine Potentiates Strychnine-Induced Convulsions: Role of NMDA Receptors Alice A. Larson and Alvin J. Beitz Department of Veterinary Biology ...
Amabeoku, George and Raymond Chandomba: Strychnine-induced seizures in mice: the role of noradrenaline. Prog. Neuro-psyohopharmacol. & Biol. Psychiat. 1994, : 3 ... Abstract Amabeoku, George and Raymond Chandomba ...






  • v.
  • 誘発する、誘導する、誘起する、導入する、引き起こす

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「reason or establish by induction」

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「〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する」

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「cause to arise; "induce a crisis"」
bring on

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「produce electric current by electrostatic or magnetic processes」

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「cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa"」
stimulate, cause, have, get, make

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「cause to occur rapidly; "the infection precipitated a high fever and allergic reactions"」
stimulate, rush, hasten


  [★] てんかん発作

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「a sudden occurrence (or recurrence) of a disease; "he suffered an epileptic seizure"」
ictus, raptus

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「〈U〉〈C〉つかむ(つかまれる)こと / 〈U〉〈C〉強奪;差し押さえ;逮捕 / 〈C〉(病気・恐怖などが)襲うこと,発作」

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「the taking possession of something by legal process」


  [★] ストリキニーネ

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「an alkaloid plant toxin extracted chiefly from nux vomica; formerly used as a stimulant」

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  • v.
  • (induceの過去分詞)誘導される、引き起こされる
hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎

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「brought about or caused; not spontaneous; "a case of steroid-induced weakness"」