WordNet

any of several hemolysins derived from strains of streptococcus

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/09 22:54:47」(JST)

wiki en

Streptolysin is a streptococcal hemolytic exotoxin.^[1]^[2]

Types include streptolysin O (SLO), which is oxygen-labile, and streptolysin S (SLS), which is oxygen-stable.^[3]

An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre.

Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oxygen. Another difference is that that SLO is antigenic, while SLS is not antigenic due to its small size.

References

^ "streptolysin" at Dorland's Medical Dictionary
^ Streptolysin at the US National Library of Medicine Medical Subject Headings (MeSH)
^ Sierig G, Cywes C, Wessels MR, Ashbaugh CD (January 2003). "Cytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococci". Infect. Immun. 71 (1): 446–55. doi:10.1128/IAI.71.1.446-455.2003. PMC 143243. PMID 12496195.

This medical article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. A群レンサ球菌：病原性因子および発症機序 group a streptococcus virulence factors and pathogenic mechanisms
2. 急性リウマチ熱の臨床症状および診断 clinical manifestations and diagnosis of acute rheumatic fever
3. C群およびG群レンサ球菌感染症 group c and group g streptococcal infection
4. 成人における急性咽頭炎の評価 evaluation of acute pharyngitis in adults
5. 結節性紅斑 erythema nodosum

English Journal

Unique Genomic Arrangements in an Invasive Serotype M23 Strain of Streptococcus pyogenes Identify Genes That Induce Hypervirulence.

Bao Y1, Liang Z2, Booyjzsen C2, Mayfield JA2, Li Y3, Lee SW4, Ploplis VA2, Song H3, Castellino FJ5.
Journal of bacteriology.J Bacteriol.2014 Dec 1;196(23):4089-102. doi: 10.1128/JB.02131-14. Epub 2014 Sep 15.
The first genome sequence of a group A Streptococcus pyogenes serotype M23 (emm23) strain (M23ND), isolated from an invasive human infection, has been completed. The genome of this opacity factor-negative (SOF(-)) strain is composed of a circular chromosome of 1,846,477 bp. Gene profiling showed tha
PMID 25225265

On the Connection Between Autoimmunity, tic Disorders and Obsessive-Compulsive Disorders: A Meta-Analysis on Anti-Streptolysin O Titres.

Pozzi M1, Pellegrino P, Carnovale C, Perrone V, Antoniazzi S, Perrotta C, Radice S, Clementi E.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.J Neuroimmune Pharmacol.2014 Dec;9(5):606-14. doi: 10.1007/s11481-014-9561-1. Epub 2014 Aug 5.
Anti-streptolysin O (ASO) titration is useful in the context of autoimmune pathologies, including specific cases of tic and obsessive-compulsive disorders occurring after streptococcal infections. There is currently a lack of consensus on the use of ASO titres; therefore we performed a meta-analysis
PMID 25091468

Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages.

Latvala S1, Mäkelä SM, Miettinen M, Charpentier E, Julkunen I.
Clinical and experimental immunology.Clin Exp Immunol.2014 Nov;178(2):320-33. doi: 10.1111/cei.12425.
In the present study, we have analysed the ability of Streptococcus pyogenes [Group A streptococcus (GAS)] to activate the NACHT-domain-, leucine-rich repeat- and PYD-containing protein 3 (NALP3) inflammasome complex in human monocyte-derived macrophages and the molecules and signalling pathways inv
PMID 25079511

Japanese Journal

Clostridium perfringens TpeL Induces Formation of Stress Fibers via Activation of RhoA-ROCK Signaling Pathway

, , [他], , , ,
Biological and Pharmaceutical Bulletin 38(5), 732-739, 2015
… A recombinant protein (TpeL1–525) derived from the TpeL N-terminal catalytic domain in the presence of streptolysin O (SLO) induced the formation of actin stress fibers in Madin–Darby canine kidney (MDCK) cells in a dose-dependent manner. …
NAID 130005068100

A streptolysin S homologue is essential for beta-haemolytic Streptococcus constellatus subsp constellatus cytotoxicity

Tabata A,Sato Y,Maya K,Nakano K,Kikuchi K,Whiley RA,Ohkura K,Tomoyasu T,Nagamune H
MICROBIOLOGY-SGM 160, 980-991, 2014
NAID 120005597641

Highly Sensitive and Rapid Assay of Substance P and Streptolysin O in Human Serum Using Immuno-liposomes and Gramicidin Channels

SAKAMOTO Misato,SHOJI Atsushi,SUGAWARA Masao
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 29(9), 877-883, 2013-09-10
NAID 10031196098

Related Pictures

Google Images Streptolysin S-like virulence factors: the SDS-PAGE - Streptolysin protein (ab63978) streptolysin streptolysin een soort kan streptolysin S precursor. Best Priced streptolysin o staph aureus streptolysin o streptolysin s m protein