specific

出典: meddic

  • adj.
  • (~に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
  • (比較)(限定)特定の(particular)、一定の(⇔general)
  • (~に)特有の、独特の(to)
  • (比較)(医学)(~に)渡航のある(for)。特殊な
  • (生物)(生物)種の
  • 医学)特異の
  • (物理)比の。物質固有の。単位質量・長さ・面積・容積で


n.


specificallyspecificity

WordNet   license wordnet

「stated explicitly or in detail; "needed a specific amount"」

WordNet   license wordnet

「a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"」

WordNet   license wordnet

「(sometimes followed by `to'」

WordNet   license wordnet

「being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"」

WordNet   license wordnet

「relating to or distinguishing or constituting a taxonomic species; "specific characters"」

PrepTutorEJDIC   license prepejdic

「《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)」

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/05 09:08:49」(JST)

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英文文献

  • Demasking of epithelial cell adhesion molecule (EpCAM) on circulating epithelial tumor cells by Tween®20 treatment in breast cancer patients.
  • Hekimian K, Stein EL, Pachmann U, Pachmann K.AbstractAbstract Background: The epithelial cell adhesion molecule (EpCAM) embedded in the plasma membrane of circulating epithelial tumor cells (CETC) is used for detection and enrichment of circulating tumor cells in peripheral blood and as a target for anti-epithelial antibodies elicited during immune response in anti-tumor immunization. Although an efficient immune response against EpCAM can be generated, the clinical application of such approaches has not been successful so far and the detection of circulating epithelial cells is highly variable. One reason for these discrepancies may be that not all circulating tumor cells are equally accessible for the specific antibody. A possible reason might be masking of EpCAM by glycoproteins or membrane lipoproteins preventing antibody binding. Methods: We have tested the application of detergents as demasking agents known to be successful in demasking red blood cell epitopes and determined how and in which way they affect integral membrane proteins and membrane lipids. Results: The results showed that the polysorbate Tween®20, a non-ionic detergent like organic solvent is able to demask EpCAM on CETC and makes it better accessible to its specific antibody retaining at the same time full cell viability. Conclusions: The data presented in this study suggest that EpCAM is present on part of circulating tumor cells in a masked form and that it is possible to demask EpCAM on CETC of breast cancer patients using Tween®20 treatment. But further studies are needed to elucidate the mechanism of demasking.
  • Clinical chemistry and laboratory medicine : CCLM / FESCC.Clin Chem Lab Med.2012 Dec 7;50(4):701-8. doi: 10.1515/cclm.2011.812.
  • Abstract Background: The epithelial cell adhesion molecule (EpCAM) embedded in the plasma membrane of circulating epithelial tumor cells (CETC) is used for detection and enrichment of circulating tumor cells in peripheral blood and as a target for anti-epithelial antibodies elicited during immune re
  • PMID 22505561
  • Comparison of personality characteristics on the bear-fedio inventory between patients with epilepsy and those with non-epileptic seizures.
  • Tremont G, Smith MM, Bauer L, Alosco ML, Davis JD, Blum AS, Lafrance WC.AbstractThis study used the Bear-Fedio Personality Inventory (BFI) to compare 41 individuals with temporal lobe epilepsy (TLE) and 37 with psychogenic non-epileptic seizures (NES). Both groups exhibited similar elevations on the BFI, although TLE individuals show greater endorsement of at least one hypergraphia symptom, as compared with those with NES. The correlates of the BFI with demographic and seizure characteristics differed between the groups. These results argue against a specific TLE personality syndrome and suggest that personality characteristics may be related to the experience of having repeated seizures, rather than the specific underlying pathophysiology of temporal lobe epilepsy.
  • The Journal of neuropsychiatry and clinical neurosciences.J Neuropsychiatry Clin Neurosci.2012 Dec 1;24(1):47-52.
  • This study used the Bear-Fedio Personality Inventory (BFI) to compare 41 individuals with temporal lobe epilepsy (TLE) and 37 with psychogenic non-epileptic seizures (NES). Both groups exhibited similar elevations on the BFI, although TLE individuals show greater endorsement of at least one hypergra
  • PMID 22450613
  • Fixation Strategies in Total Hip Arthroplasty.
  • Geesink RD.SourceEmeritus Professor of Orthopaedic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Surgical technology international.Surg Technol Int.2012 Dec 1;XXI:240-247. [Epub ahead of print]
  • Substantial progress has been achieved in cementless arthroplasty in the recent decades where cementless arthroplasty has evolved from pressfit implantation to porous-coated and later HA-coated implant fixation as its ultimate current state-of-the-art incarnation. Key factors for success are adequat
  • PMID 22504997
  • Update 2012: Regenerative Medicine in Wounds: Current Use of Growth Factors, Cell Therapy, and Negative Pressure Wound Therapy for Chronic Wounds.
  • Lantis Ii JC.SourceChief of the Division of Vascular/Endovascular Surgery, St Luke's-Roosevelt Hospital, Associate Clinical Professor of Surgery, Columbia University, New York, New York.
  • Surgical technology international.Surg Technol Int.2012 Dec 1;XXI:43-49. [Epub ahead of print]
  • While we move toward the brink of being able to regenerate or replace human cells, tissues, or organs to restore or establish normal function, we are not there yet. The techniques that are available and being brought to bear on the field of chronic wounds include: growth factors, gene therapy, stem
  • PMID 22504969

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  • A Hypersweet Protein: Removal of The Specific Negative Charge at Asp21 Enhances Thaumatin Sweetness.
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関連リンク

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(physics) characteristic of a property of a particular substance, esp in relation to the same property of a standard reference substance: specific gravity characteristic of a property of a particular substance per unit mass, length, area ...

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★リンクテーブル★
先読みgeneral
リンク元100Cases 28」「specificity」「specifically」「ratio」「特異的
拡張検索type I site-specific deoxyribonuclease」「regiospecific」「bispecific antibody

general」

  [★]

  • adj.
  • 一般の、総体的な、全般/総合的な、包括的な、普遍的な(opp. special)
  • (専門的でなく)一般的な。通常の。雑多な、雑用の
  • (詳細でなく)概括的な、大体の、概略の(opp. particular)。漠然とした、あいまいな(vague)
  • n.


commoncommonlyconventionalgenerallygenericgenericallyin generalnormalnormallyordinarilyordinarypopularprevailingsystemictotal bodyuniversaluniversallyusualusuallywhole bodywhole-body

WordNet   license wordnet

「somewhat indefinite; "bearing a general resemblance to the original"; "a general description of the merchandise"」

WordNet   license wordnet

「a general officer of the highest rank」
full general

WordNet   license wordnet

「the head of a religious order or congregation」
superior general

WordNet   license wordnet

「a fact about the whole (as opposed to particular); "he discussed the general but neglected the particular"」

PrepTutorEJDIC   license prepejdic

「(あるグループ)『全部の』,全部を含む / 『世間一般の』,広く行き渡った / 『一般の』,専門的でない / 『大体の』,概略の / 『陸軍大将』;(陸軍の)『将軍』,将官 / 概して,一般に」

WordNet   license wordnet

「affecting the entire body; "a general anesthetic"; "general symptoms"」

WordNet   license wordnet

「applying to all or most members of a category or group; "the general public"; "general assistance"; "a general rule"; "in general terms"; "comprehensible to the general reader"」

WordNet   license wordnet

「command as a general; "We are generaled by an incompetent!"」

WordNet   license wordnet

「not specialized or limited to one class of things; "general studies"; "general knowledge"」

WordNet   license wordnet

「prevailing among and common to the general public; "the general discontent"」


100Cases 28」

  [★]

☆case28 慢性経過する胸痛
症例
25歳 女性
主訴胸痛
現病歴:2年前より胸痛出現と消退が持続していた。胸痛は6ヶ月間は収まっていたが、最近10ヶ月間は出現してきていた。胸痛は胸部左方
にあり、左腋窩に放散していた。胸痛は胸を締め付けられる、あるいは握りつぶされるような痛みであり、5-30分持続した。胸痛はどんなときでも出現することがあった。労作時によく出現したが、ある場合には安静時にも出現し、特に夕方に出現した。胸痛には息切れが伴うことが良くあった。胸痛出現したときには、どんなときでも身動きができなくなり、痛みと共にが遠くなったり、めまいをかんじた。時々、胸痛と共に動悸があった。動悸は強く感じられたが、心拍動はしっかりしていた(steady heart beat)。
既往歴
 ・15歳 虫垂摘出
 ・30歳 腹症(irregular bowel habit)と腹痛精査(be investigated for)をうけたが、診断がつかず(no specific diagnosis was arrived at)。症状現在持続
 ・季節性鼻炎(seasonal rhinitis)
 ・2年前コレステロール測定したが4.1 mmol/Lであった
基準値(HIM A-10)
単位mg/dL (mmol/L)
desirable: <200 (<5.17)
borderline high: 200-239 (5.17-6.18)
high: ≧240 (≧6.21)
生活歴medical secretaryとして働いている。既婚子供はいない
家族歴:祖父が1年前MI死亡(77歳)。家族の数人に花粉症、あるいは喘息がある。
身体所見 examination
 血圧:102/65 mmHg脈拍:78/分、整。心音に異常所見はみとめない。左胸部、胸骨左部、乳腺下部に圧痛呼吸数22/分。肺に異常所見を認めない。左腸骨窩に圧痛
検査所見 investigations
 ECG
問診(S) 診察(O) 検査結果(O)
胸痛 左胸部、胸骨左部、乳腺下部に圧痛 ECG(異常なし)
息切れ 呼吸数多い(22/分)  
気が遠くなる感じ 左腸骨窩に圧痛  
めまい    
動悸    
排便習慣不順    
腹痛    
祖父が心筋梗塞死亡    
コレステロール値正常    
家族歴花粉症喘息あり    
アレルギー性鼻炎    
虫垂摘出    
     
1. 心臓神経症疑い    
2. 過敏性腸症候群 2 + 3 = 1を支持  
3. 心疾患心配する環境要因    
4. 喘息による胸痛を疑う要因    


specificity」

  [★]

  • n.
sensitivityspecialityspecific

WordNet   license wordnet

「the quality of being specific rather than general; "add a desirable note of specificity to the discussion"; "the specificity of the symptoms of the disease"」

WordNet   license wordnet

「the quality of being specific to a particular organism; "host specificity of a parasite"」

PrepTutorEJDIC   license prepejdic

「特性を持っていること;特質,特性」


specifically」

  [★]

  • adv.
  • 明確に、はっきりと
  • 特に、とりわけ(especially)
  • (文修飾)(しばしばmore~)もっと正確に言えば、すなわち、具体的に言えば
  • 他とは異なった、珍しく
specific

WordNet   license wordnet

「in distinction from others; "a program specifically for teenagers"; "he is interested specifically in poisonous snakes"」

PrepTutorEJDIC   license prepejdic

「明確に(clearly) / 特に,とりわけ / すなわち,言い替えれば(namely)」


ratio」

  [★]

fractionpercentageproportionratespecific

WordNet   license wordnet

「the relative magnitudes of two quantities (usually expressed as a quotient)」

PrepTutorEJDIC   license prepejdic

「『比』,比率,『割合』;『比例』」


特異的」

  [★]

specificspecifically
特異性


type I site-specific deoxyribonuclease」

  [★]

I型部位特異的デオキシリボヌクレアーゼ

type I restriction endonucleasetype I restriction enzyme


regiospecific」

  [★]

  • 位置特異的な、位置特異性の
regiospecificallytopographic

bispecific antibody」

  [★]

二重特異性抗体二特異性抗体

diabody




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