sodium nitroprusside

出典: meddic

ニトロプルシドニトロプルシドナトリウム, sodium nitroprusside SNP

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/10/29 23:56:44」(JST)

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  • The mediation of platelet quiescence by NO-releasing polymers via cGMP-induced serine 239 phosphorylation of vasodilator-stimulated phosphoprotein.
  • Major TC, Handa H, Brisbois EJ, Reynolds MM, Annich GM, Meyerhoff ME, Bartlett RH.SourceDepartment of Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA. Electronic address:
  • Biomaterials.Biomaterials.2013 Nov;34(33):8086-96. doi: 10.1016/j.biomaterials.2013.07.041. Epub 2013 Jul 29.
  • Nitric oxide (NO) releasing (NORel) materials have been shown to create localized increases in NO concentration by the release of NO from a diazeniumdiolate-containing or S-nitrosothiol-containing polymer coating and the improvement of extracorporeal circulation (ECC) hemocompatibility. However, the
  • PMID 23906514
  • Complement activation is critical for placental ischemia-induced hypertension in the rat.
  • Lillegard KE, Johnson AC, Lojovich SJ, Bauer AJ, Marsh HC, Gilbert JS, Regal JF.SourceDepartment of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN 55812, USA.
  • Molecular immunology.Mol Immunol.2013 Nov;56(1-2):91-7. doi: 10.1016/j.molimm.2013.04.009. Epub 2013 May 15.
  • Preeclampsia is a major obstetric problem defined by new-onset hypertension and proteinuria associated with compromised placental perfusion. Although activation of the complement system is increased in preeclampsia compared to normal pregnancy, it remains unclear whether excess complement activation
  • PMID 23685261
  • Do iodinated nano-emulsions designed for preclinical vascular imaging alter the vascular reactivity in rat aorta?
  • Anton N, Atzenhoffer M, Daubeuf F, Li X, Schini-Kerth VB, Delmotte B, Vandamme TF, Chataigneau T.SourceUMR 7199 CNRS, Laboratoire de Conception et Application de Molécules Bioactives, équipe de Pharmacie Biogalénique, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, BP 60024, 67401 Illkirch Cedex, France.
  • International journal of pharmaceutics.Int J Pharm.2013 Sep 15;454(1):143-8. doi: 10.1016/j.ijpharm.2013.07.007. Epub 2013 Jul 10.
  • This study proposes a new methodology to evaluate the putative consequences of the long-lasting circulation in the blood pool of nanoparticulate systems widely used in nanomedicine, Indeed, the blood pool contrast agent for micro-computed tomography, i.e. iodinated nano-emulsions, have recently been
  • PMID 23850235


  • Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model
  • Mikami Shinsuke,Nakashima Ayumu,Nakagawa Keigo,Maruhashi Tatsuya,Iwamoto Yumiko,Kajikawa Masato,Matsumoto Takeshi,Kihara Yasuki,Chayama Kazuaki,Noma Kensuke,Ochi Mitsuo,Nishimura Masahiro,Tsuji Koichiro,Kato Yukio,Goto Chikara,Higashi Yukihito
  • PLoS ONE 8(7), e67739, 2013-07-04
  • … Background:The purpose of this study was to determine whether autologous mesenchymal stem cells (MSCs) implantation improves endothelial dysfunction in a rabbit ischemic limb model.Methods:We evaluated the effect of MSC implantation on limb blood flow (LBF) responses to acetylcholine (ACh), an endothelium-dependent vasodilator, and sodium nitroprusside (SNP), an endothelium-independent vasodilator, in rabbits with limb ischemia in which cultured MSCs were implanted (n = 20) or saline was injected as a control group (n = 20). …
  • NAID 120005311939
  • Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells
  • Ota Yuki,Kawanai Takuya,Watanabe Ryo,Nishimura Akira,Ago Yukio,Takuma Kazuhiro,Matsuda Toshio
  • Journal of Pharmacological Sciences 121(4), 351-354, 2013
  • … There was no difference in the cytotoxic effects of the NO donors sodium nitroprusside and S-nitroso-N-acetylpenicillamine between control and transfected cells. …
  • NAID 130003382585
  • Protective Effect of Luteolin on an Oxidative-Stress Model Induced by Microinjection of Sodium Nitroprusside in Mice
  • Nazari Qand Agha,Kume Toshiaki,Takada-Takatori Yuki [他],Izumi Yasuhiko,Akaike Akinori
  • Journal of Pharmacological Sciences 122(2), 109-117, 2013
  • … The purpose of this study was to examine whether luteolin can protect against sodium nitroprusside (SNP)-induced oxidative damage in mouse brain. …
  • NAID 130003362709


Sodium nitroprusside is the inorganic compound with the formula Na2[Fe(CN)5 NO]·2H2O. This red-coloured salt, which is often abbreviated SNP, is a potent vasodilator. The sodium salt dissolves in water and to a lesser extent in ethanol to ...






ニトロプルシドナトリウム, sodium nitroprusside SNP

  • 血管拡張薬・緊急降圧薬、グアニル酸シクラーゼ活性化





sodium nitroprusside


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「a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt)」
Na, atomic number 11

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