skeletal muscle

出典: meddic

See also Muscle; Muscle contraction

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/19 19:16:14」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.


  • Retinoblastoma Protein Knockdown Favors Oxidative Metabolism and Glucose and Fatty Acid Disposal in Muscle Cells.
  • Petrov PD1, Ribot J1, López-Mejía IC2, Fajas L2, Palou A1, Bonet ML1.
  • Journal of cellular physiology.J Cell Physiol.2016 Mar;231(3):708-18. doi: 10.1002/jcp.25121.
  • Deficiency in the retinoblastoma protein (Rb) favors leanness and a healthy metabolic profile in mice largely attributed to activation of oxidative metabolism in white and brown adipose tissues. Less is known about Rb modulation of skeletal muscle metabolism. This was studied here by transiently kno
  • PMID 26241807
  • Selective Life-Long Skeletal Myofiber-Targeted VEGF Gene Ablation Impairs Exercise Capacity in Adult Mice.
  • Tang K1, Gu Y1, Dalton ND1, Wagner H1, Peterson KL1, Wagner PD1, Breen EC1.
  • Journal of cellular physiology.J Cell Physiol.2016 Feb;231(2):505-11. doi: 10.1002/jcp.25097.
  • Exercise is dependent on adequate oxygen supply for mitochondrial respiration in both cardiac and locomotor muscle. To determine whether skeletal myofiber VEGF is critical for regulating exercise capacity, independent of VEGF function in the heart, ablation of the VEGF gene was targeted to skeletal
  • PMID 26201683
  • Potential Role of Glycogen Synthase Kinase-3β in Regulation of Myocardin Activity in Human Vascular Smooth Muscle Cells.
  • Zhou YX1, Shi Z1, Singh P1, Yin H1, Yu YN2, Li L2, Walsh MP1, Gui Y3, Zheng XL1.
  • Journal of cellular physiology.J Cell Physiol.2016 Feb;231(2):393-402. doi: 10.1002/jcp.25084.
  • Glycogen synthase kinase (GSK)-3β, a serine/threonine kinase with an inhibitory role in glycogen synthesis in hepatocytes and skeletal muscle, is also expressed in cardiac and smooth muscles. Inhibition of GSK-3β results in cardiac hypertrophy through reducing phosphorylation and increasing transc
  • PMID 26129946


  • Relationship between Low Free Testosterone Levels and Loss of Muscle Mass
  • Yuki Atsumu,Otsuka Rei,Kozakai Rumi,Kitamura Itsuko,Okura Tomohiro,Ando Fujiko,Shimokata Hiroshi,大藏 倫博
  • Scientific reports 3, 1818, 2013-05-00
  • … We assessed longitudinal relationships between baseline testosterone and muscle mass changes in Japanese men. … Appendicular muscle mass (AMM) was measured with dual-energy X-ray absorptiometry at baseline and follow-up examinations. … The cut-off point of sarcopenia was defined as a skeletal muscle index (AMM/height2) < … Low FT may be a predictor of risk for muscle loss in Japanese men. …
  • NAID 120005293659
  • Fetal skeletal muscle progenitors have regenerative capacity after intramuscular engraftment in dystrophin deficient mice.
  • Sakai Hiroshi,Sato Takahiko,Sakurai Hidetoshi,Yamamoto Takuya,Hanaoka Kazunori,Montarras Didier,Sehara-Fujisawa Atsuko
  • PloS one 8(5), 2013-05-00
  • Muscle satellite cells (SCs) are stem cells that reside in skeletal muscles and contribute to regeneration upon muscle injury. … SCs arise from skeletal muscle progenitors expressing transcription factors Pax3 and/or Pax7 during embryogenesis in mice. … However, it is unclear whether these fetal progenitors possess regenerative ability when transplanted in adult muscle. …
  • NAID 120005245143
  • 電気刺激による培養骨格筋細胞の肥大効果
  • 岩田 全広,西浜 かすり,土田 和可子,鈴木 重行
  • 日本福祉大学健康科学論集 16, 1-7, 2013-03-30
  • … Electrical pulse stimulation (EPS) has a hypertrophic effect on mammalian skeletal muscle, and it is usually used to prevent muscle atrophy and improve muscle strength during rehabilitation therapy. … However, there is no clear explanation for the mechanisms of how EPS induces muscle hypertrophy. … Thus, to clarify the mechanisms, we performed cell culture of skeletal myotubes (C2C12 myotubes). …
  • NAID 110009573838


Skeletal Muscle is a peer-reviewed, open access, online journal that publishes articles investigating molecular mechanisms underlying the biology of skeletal muscle. A wide range of skeletal muscle biology is included: development ...
Skeletal muscle fibers are not all the same. Traditionally, they were categorized depending on their varying color, which is a reflection of myoglobin content. Red Fibers: Those containing high levels of myoglobin and oxygen storing ...



リンク元骨格筋」「anterior tibial muscle」「soleus muscle」「voluntary muscle」「plantaris muscle
拡張検索skeletal muscle dihydropyridine receptor



skeletal muscle (K)
musculus skeleti
横紋筋 striated muscle



  • 1. 運動神経末端に活動電位が伝わると、神経末端周辺に局在する電位依存性Ca2+チャネルが開き、神経細胞内にCa2+が流入する。
  • 2. 神経細胞内のCa2+濃度が上昇すると、シナプス顆粒が開口分泌され、神経伝達物質であるアセチルコリンがシナプス間隙に放出される。
  • 3. アセチルコリンはシナプス間隙を経て筋細胞膜上のアセチルコリン受容体に結合する。
  • 4. アセチルコリン受容体は陽イオンチャネルであり、一時的に陽イオンを透過させ、筋細胞膜を脱分極する。
  • 5. アセチルコリンはアセチルコリンエステラーゼによりコリンに分解されて、神経細胞に取り込まれる。
  • 6. 筋細胞で局所的な脱分極が起こると、周辺の電位依存性Na+チャネルが開き、脱分極が筋細胞全体に広がる。
  • 7. 脱分極はT細管に伝わり、T細管に存在する電位依存性のタンパク質の構造を変化させ、筋小胞体の特殊な構造である終末槽上のCa2+放出チャネルを開く。
  • 8. 筋小胞体中のCa2+が細胞質に拡散する。
  • 9. ここで、筋収縮に関わるアクチンフィラメントにトロポミオシンとトロポニンが結合し、収縮開始を妨げているが、Ca2+がトロポニンに結合すると、トロポミオシンがアクチンフィラメント上で場所を変える。
  • 10. この結果、トロポミオシンが覆い隠していたアクチンフィラメントのミオシン結合部位が露出する。
  • 11. ミオシンはATPの加水分解のエネルギーを使って、アクチンフィラメントに結合できる構造をとり、アクチンに結合する。
  • 12. ミオシンがアクチンフィラメントで首振り運動をすることで筋収縮が起こる。

anterior tibial muscle」



gastrocnemius musclemusculus tibias anteriorplantaris muscleskeletal musclesoleus muscletibialis anterior musclevoluntary muscle

soleus muscle」



anterior tibial musclegastrocnemius musclemusculus soleusplantaris muscleskeletal musclevoluntary muscle

voluntary muscle」



anterior tibial musclegastrocnemius muscleplantaris muscleskeletal musclesoleus muscle

plantaris muscle」



anterior tibial musclegastrocnemius muscleskeletal musclesoleus musclevoluntary muscle

skeletal muscle dihydropyridine receptor」

  [★] 骨格筋ジヒドロピリジン受容体



  • n.

WordNet   license wordnet

「make one''s way by force; "He muscled his way into the office"」

WordNet   license wordnet

「animal tissue consisting predominantly of contractile cells」
muscular tissue

WordNet   license wordnet

「one of the contractile organs of the body」

WordNet   license wordnet

「authority or power or force (especially when used in a coercive way); "the senators used their muscle to get the party leader to resign"」

PrepTutorEJDIC   license prepejdic

「〈U〉(動物体の組織としての)『筋肉』,筋(きん);〈C〉(体の各部を動かす)筋肉 / 〈U〉力,(特に)筋力,腕力 / 《俗に》(…に)強引に割り込む《+『in on』(『into, through』)+『名』》」



  • adj.
  • 骨格の、骸骨の(ような)
scaffold, skeleton

WordNet   license wordnet

「of or relating to or forming or attached to a skeleton; "the skeletal system"; "skeletal bones"; "skeletal muscles"」

PrepTutorEJDIC   license prepejdic




PrepTutorEJDIC   license prepejdic

「筋肉の,筋力のある / 力ずくの」