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English Journal

New insights into the mode of action of the actin ADP-ribosylating virulence factors Salmonella enterica SpvB and Clostridium botulinum C2 toxin.

Barth H, Aktories K.SourceInstitut fur Pharmakologie und Toxikologie, Universitatsklinikum Ulm, Germany.
European journal of cell biology.Eur J Cell Biol.2011 Nov;90(11):944-50. Epub 2011 Jan 17.
The C2 toxin from Clostridium botulinum represents the prototype of the family of binary actin-ADP-ribosylating toxins. These toxins covalently transfer ADP-ribose from nicotinamide adenine dinucleotide (NAD(+)) onto arginine-177 of actin in the cytosol of eukaryotic cells resulting in depolymerizat
PMID 21247657

Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays.

Troiani S, Lupi R, Perego R, Re Depaolini S, Thieffine S, Bosotti R, Rusconi L.SourceDepartment of Biotechnology, BU Oncology, Nerviano Medical Sciences Srl, Italy.
The FEBS journal.FEBS J.2011 Oct;278(19):3676-87. doi: 10.1111/j.1742-4658.2011.08286.x. Epub 2011 Sep 6.
Poly(ADP-ribose) polymerase-2 (PARP2) belongs to the ADP-ribosyltransferase family of enzymes that catalyze the addition of ADP-ribose units to acceptor proteins, thus affecting many diverse cellular processes. In particular, PARP2 shares with PARP1 and, as recently highlighted, PARP3 the sole prope
PMID 21812934

鎌田洋一,服部恭代
The journal of veterinary medical science 69(1), 37-42, 2007-01-25
神経成長因子,レチノイン酸,ジブチリルcAMP,ガングリオシドG_<Q1b>,およびボツリヌスC3酵素のヒト神経芽細胞腫GOTO細胞における神経分化能を比較評価した.C3酵素はADPリボース転移酵素で,低分子量GTP結合タンパク質であるRhoタンパク質を不活性化する.C3酵素は検定した薬剤のなかでもっとも速やかにGOTO細胞を神経細胞に分化させ,またもっとも強く神経細胞を連結させ,ネッ …
NAID 110006151574

Neural Differentiation of Human Neuroblastoma GOTO Cells via a Rho-Rho Kinase-Phosphorylation Signal Transduction and Continuous Observation of a Single GOTO Cell during Differentiation

KAMATA Yoichi,HATTORI Yasuyo
Journal of Veterinary Medical Science 69(1), 37-42, 2007
… C3 exoenzyme is an ADP-ribosyltransferase inactivating Rho protein (a small GTP-binding protein). …
NAID 130000447724

リンク元	「リボシル基転移酵素」「リボシルトランスフェラーゼ」
拡張検索	「hypoxanthine phosphoribosyltransferase gene mutation」「hypoxanthine-guanine phosphoribosyltransferase」「ATP phosphoribosyltransferase」