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「an inhaled antiviral agent (trade name Virazole) that may be used to treat serious virus infections」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/09/06 21:18:34」(JST)

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  • Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients.
  • Boltjes A, Op den Brouw ML, Biesta PJ, Binda RS, van der Molen RG, Boonstra A, Janssen HL, Woltman AM.SourceLiver Unit, Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, 's Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.
  • Molecular immunology.Mol Immunol.2013 Jan;53(1-2):72-8. Epub 2012 Jul 20.
  • The combination of ribavirin and peginterferon is the current standard of anti-viral treatment for chronic HCV patients. However, little is known on the mode of action of ribavirin in the anti-viral treatment of HCV patients. To investigate the immunomodulatory mechanism of ribavirin, we studied peg
  • PMID 22814486
  • Different mechanisms of hepatitis C virus RNA polymerase activation by cyclophilin A and B in vitro.
  • Weng L, Tian X, Gao Y, Watashi K, Shimotohno K, Wakita T, Kohara M, Toyoda T.SourceUnit of Viral Genome Regulation, Institut Pasteur of Shanghai, Chinese Academy of Sciences, 411 Hefei Road, 200025 Shanghai, People's Republic of China.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2012 Dec;1820(12):1886-92. doi: 10.1016/j.bbagen.2012.08.017. Epub 2012 Aug 28.
  • BACKGROUND: Cyclophilins (CyPs) are cellular proteins that are essential to hepatitis C virus (HCV) replication. Since cyclosporine A was discovered to inhibit HCV infection, the CyP pathway contributing to HCV replication is a potential attractive stratagem for controlling HCV infection. Among them
  • PMID 22954804


  • The Safety Profile of Telaprevir-Based Triple Therapy in Clinical Practice : A Retrospective Cohort Study
  • Risk Factors for Treatment Discontinuation Caused by Adverse Events When Using Telaprevir, Peginterferon, and Ribavirin to Treat Chronic Hepatitis C : A Real-World Retrospective Cohort Study
  • Reduced telaprevir dosing in combination therapy for patients with chronic hepatitis C


Ribavirin is also sometimes used to treat viral hemorrhagic fevers (viruses that can cause bleeding inside and outside of the body, problems with many organs, and death). In the event of biological warfare, ribavirin may be ...
Ribavirin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. ... Pediatric Patients Peginterferon alfa-2a is administered as 180 mcg/1.73m 2 x BSA ...


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ribavirin, RBV
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