rejection reactions

出典: meddic

拒絶反応, RR

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  • Inducible costimulator (ICOS) up-regulation on activated T cells in chronic graft-versus-host disease after dog leukocyte antigen-nonidentical hematopoietic cell transplantation: a potential therapeutic target.
  • Sato M, Storb R, Loretz C, Stone D, Mielcarek M, Sale GE, Rezvani AR, Graves SS.Source1 Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA. 2 Division of Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA. 3 Department of Pathology, University of Washington School of Medicine, Seattle, WA. 4 Address correspondence to: Dr. Scott S. Graves, Clinical Research Division, Fred Hutchinson Cancer Research Center, P.O. Box 19024, D1-100 1100 Fairview Avenue North, Seattle, WA 98109.
  • Transplantation.Transplantation.2013 Jul 15;96(1):34-41. doi: 10.1097/TP.0b013e318295c025.
  • BACKGROUND: Inducible costimulator (ICOS), a member of the CD28 family of costimulatory molecules, is induced on CD4 and CD8 T cells after their activation. ICOS functions as an essential immune regulator and ICOS blockade is a potential approach to immune modulation in allogeneic transplantation. H
  • PMID 23694952
  • Concise Review: Immunological Properties of Ocular Surface and Importance of Limbal Stem Cells for Transplantation.
  • Shaharuddin B, Ahmad S, Meeson A, Ali S.SourceInstitute of Genetic Medicine and.
  • Stem cells translational medicine.Stem Cells Transl Med.2013 Jul 1. [Epub ahead of print]
  • Cornea transplantation has been considered to be different from other solid organ transplantation because of the assumed immune-privileged state of the anterior chamber of the eye. Three major lines of thought regarding the molecular mechanisms of immune privilege in the eye are as follows: (a) anat
  • PMID 23817133
  • Treatment of Graft-versus-Host Disease with Naturally Occurring T Regulatory Cells.
  • Trzonkowski P, Dukat-Mazurek A, Bieniaszewska M, Marek-Trzonkowska N, Dobyszuk A, Juścińska J, Dutka M, Myśliwska J, Hellmann A.SourceDepartment of Clinical Immunology and Transplantology, Medical University of Gdańsk, Ul. Dębinki 1, 80-211, Gdańsk, Poland,
  • BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.BioDrugs.2013 Jun 28. [Epub ahead of print]
  • A significant body of evidence suggests that treatment with naturally occurring CD4+CD25+ T regulatory cells (Tregs) is an appropriate therapy for graft-versus-host disease (GvHD). GvHD is a major complication of bone marrow transplantation in which the transplanted immune system recognizes recipien
  • PMID 23813436


  • 薬学的介入記録票解析による病棟薬剤師業務の効果検証
  • 高分子を利用した細胞の表面修飾と糖尿病治療への応用
  • Downregulating immunogenicity of Schwann cells via inhibiting a potential target of class II transactivator (CIITA) gene


transplant rejection Graft rejection, organ rejection, tissue rejection Immunology The constellation of host immune responses evoked when an allograft tissue is transplanted into a recipient; rejection phenomena may be minimized by ...
Research Article Defensive Physiological Reactions to Rejection The Effect of Self-Esteem and Attentional Control on Startle Responses Anett Gyurak and O¨zlem Ayduk University of California, Berkeley ABSTRACT—We examined ...






rejectionallograft rejection, graft rejection, rejection reaction RR


  反応時期 原因 治療
超急性拒絶反応 24時間以内 体液性 レシピエントの抗HLA抗体 移植臓器の摘出 免疫抑制薬無効
急性拒絶反応 1週間後~3ヶ月後 細胞性 レシピエント抗原提示細胞によるドナー抗原提示?   免疫抑制薬有効
慢性拒絶反応 3ヶ月後~ 体液性   再移植 免疫抑制薬無効






WordNet   license wordnet

「a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age"」

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「doing something in opposition to another way of doing it that you don''t like; "his style of painting was a reaction against cubism"」

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「(mechanics) the equal and opposite force that is produced when any force is applied to a body; "every action has an equal and opposite reaction"」

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「a response that reveals a person''s feelings or attitude; "he was pleased by the audience''s reaction to his performance"; "John feared his mother''s reaction when she saw the broken lamp"」

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「an idea evoked by some experience; "his reaction to the news was to start planning what to do"」

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「extreme conservatism in political or social matters; "the forces of reaction carried the election"」

PrepTutorEJDIC   license prepejdic

「{名}(…に対する)『反応』《+『to』+『名』》 / 〈U〉(…に対する)(政治的・社会的な)『反動』,逆コース《+『against』+『名』》 / 〈U〉〈C〉化学反応,化学変化 / 〈U〉〈C〉(物理学で)反作用」



  • n.

WordNet   license wordnet

「the act of rejecting something; "his proposals were met with rejection"」

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「(medicine) an immunological response that refuses to accept substances or organisms that are recognized as foreign; "rejection of the transplanted liver"」

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「the state of being rejected」

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「the speech act of rejecting」

PrepTutorEJDIC   license prepejdic

「〈U〉〈C〉断ること,拒絶;却下 / 〈C〉廃棄物」