ras gene

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/07/12 23:39:04」(JST)

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  • Importance of epigenetic changes in cancer etiology, pathogenesis, clinical profiling, and treatment: What can be learned from hematologic malignancies?
  • Vecchio L, Seke Etet PF, Kipanyula MJ, Krampera M, Nwabo Kamdje AH.SourceLaboratory of Cytometry, Institute of Molecular Genetics, CNR, University of Pavia, 27100 Pavia, Italy.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2013 Aug;1836(1):90-104. doi: 10.1016/j.bbcan.2013.04.001. Epub 2013 Apr 17.
  • Epigenetic alterations represent a key cancer hallmark, even in hematologic malignancies (HMs) or blood cancers, whose clinical features display a high inter-individual variability. Evidence accumulated in recent years indicates that inactivating DNA hypermethylation preferentially targets the subse
  • PMID 23603458
  • Oncoapoptotic signaling and deregulated target genes in cancers: Special reference to oral cancer.
  • Khan Z, Bisen PS.SourceInstitut Pasteur, Viral Neuroimmunology, CNRS URA3015, Department of Virology, 25 Rue du Docteur Roux, F-75015, Paris, France; Institut Curie, TGF-β and Oncogenesis, CNRS UMR3347/INSERM U1021, Centre Universitaire, F-91405, Orsay Cedex, France; School of Biotechnology, Jiwaji University, Gwalior, 474011 (M.P.), India. Electronic address: zakirq.khan@gmail.com.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2013 Aug;1836(1):123-45. doi: 10.1016/j.bbcan.2013.04.002. Epub 2013 Apr 17.
  • Cancer is a class of diseases characterized by uncontrolled cell growth. The development of cancer takes place in a multi-step process during which cells acquire a series of mutations that eventually lead to unrestrained cell growth and division, inhibition of cell differentiation, and evasion of ce
  • PMID 23602834
  • The transcription factor NFAT1 induces apoptosis through cooperation with Ras/Raf/MEK/ERK pathway and upregulation of TNF-α expression.
  • Robbs BK, Lucena PI, Viola JP.SourceProgram of Cellular Biology, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2013 Aug;1833(8):2016-28. doi: 10.1016/j.bbamcr.2013.04.003. Epub 2013 Apr 10.
  • Nuclear factor of activated T cells (NFAT) was described as an activation and differentiation factor in T cells. NFAT1 protein is expressed in several cell types and has been implicated in the control of the cell cycle, death and migration. Overexpression or activation of NFAT1 has been demonstrated
  • PMID 23583303


  • Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma.
  • Cooperative induction of transmembrane prostate androgen induced protein TMEPAI/PMEPA1 by transforming growth factor-β and epidermal growth factor signaling
  • Biochemical and biophysical research communications 456(2), 580-585, 2015-01
  • NAID 120005596091
  • Establishment of a syngeneic orthotopic model of prostate cancer in immunocompetent rats


The first two ras genes, HRAS and KRAS, were first identified from studies of two cancer-causing viruses, the Harvey sarcoma virus and Kirsten sarcoma virus, by Edward M. Scolnick and colleagues at the National Institutes of Health (NIH).



拡張検索H-ras gene」「N-ras gene



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H-ras gene」



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N-ras gene」



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  [★] 遺伝子

WordNet   license wordnet

「(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"」
cistron, factor

PrepTutorEJDIC   license prepejdic






WordNet   license wordnet

「informal term for information; "give me the gen on your new line of computers"」



PrepTutorEJDIC   license prepejdic

「roentgen / recto」