前核
- 関
- anterior nuclei、anterior nucleus、pronuclear、pronucleus
WordNet
- the nucleus of the ovum or sperm after fertilization but before they fuse to form the nucleus of the zygote
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/12 14:55:14」(JST)
[Wiki en表示]
The process of fertilization in the ovum of a mouse.
A pronucleus (plural: pronuclei) is the nucleus of a sperm or an egg cell during the process of fertilization, after the sperm enters the ovum, but before they fuse. Sperm and egg cells are haploid, meaning they carry half the number of chromosomes. The male and female pronuclei don't fuse, although their genetic material does. Instead, their membranes dissolve, leaving no barriers between the male and female chromosomes. Their chromosomes can then combine and become part of a single diploid nucleus in the resulting embryo, containing a full set of chromosomes.
The appearance of two pronuclei is the first sign of successful fertilization as observed during in vitro fertilisation, and is usually observed 18 hours after insemination or ICSI. The zygote is then termed a two-pronuclear zygote (2PN). Two-pronuclear zygotes transitioning through 1PN or 3PN states tend to develop into poorer-quality embryos than ones who remain 2PN throughout development,[1] and may be significant in embryo selection in IVF.
References
- ^ Reichman DE, Jackson KV, Racowsky C (May 2009). "Incidence and development of zygotes exhibiting abnormal pronuclear disposition after identification of two pronuclei at the fertilization check". Fertil. Steril. 94 (3): 965–970. doi:10.1016/j.fertnstert.2009.04.018. PMID 19476942.
External links
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Look up pronucleus in Wiktionary, the free dictionary. |
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English Journal
- Presence of the Paternal Pronucleus Assists Embryo in Overcoming Cycloheximide Induced Abnormalities in Zygotic Mitosis.
- Ortega MA1, Ko M1, Marh J1, Finberg A1, Oshiro M1, Ward WS1.
- Journal of cellular biochemistry.J Cell Biochem.2016 Aug;117(8):1806-12. doi: 10.1002/jcb.25480. Epub 2016 Jan 21.
- After fertilization, the maternal and paternal chromosomes independently proceed through pronuclear formation. These chromatin reconfigurations occur within a shared cytoplasm thus exposing both gametes to the same factors. Here, we report that continuous cycloheximide [40 μg/mL] treatment of par
- PMID 26729559
- Pretreating porcine sperm with lipase enhances developmental competence of embryos produced by intracytoplasmic sperm injection.
- Wei Y1, Fan J1, Li L1, Liu Z1, Li K1.
- Zygote (Cambridge, England).Zygote.2016 Aug;24(4):594-602. doi: 10.1017/S096719941500057X. Epub 2015 Oct 7.
- Intracytoplasmic sperm injection (ICSI) has been widely applied in humans, mice, and some domestic animals to cure human infertility, or produce genetically superior or genetically engineered animals. However, the production efficiency of ICSI in pigs remains quite low. In this study, we developed a
- PMID 26443110
- Combination of oviduct fluid and heparin to improve monospermic zygotes production during porcine in vitro fertilization.
- Batista RI1, Moro LN2, Corbin E2, Alminana C2, Souza-Fabjan JM3, de Figueirêdo Freitas VJ3, Mermillod P2.
- Theriogenology.Theriogenology.2016 Jul 15;86(2):495-502. doi: 10.1016/j.theriogenology.2016.01.031. Epub 2016 Feb 9.
- In vivo, the oviduct provides appropriate microenvironment conditions for monospermic fertilization and early embryo development. In addition, glycosaminoglycans such as heparin are present in the oviduct and have been shown to modulate the activity of oviduct-secreted proteins on the regulation of
- PMID 26964763
★リンクテーブル★
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前核
- 関
- anterior nuclei、pronuclear、pronuclei、pronucleus
[★]
- 関
- anterior nuclei、anterior nucleus、pronuclear、pronuclei
[★]
- 関
- anterior nuclei、anterior nucleus、pronuclei、pronucleus
[★]
前核
- 関
- anterior nucleus、pronuclear、pronuclei、pronucleus
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雌性前核
- 関
- female pronucleus
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雄性前核
- 関
- male pronucleus