- 関
- anterior nuclei、anterior nucleus、pronuclei、pronucleus
WordNet
- the nucleus of the ovum or sperm after fertilization but before they fuse to form the nucleus of the zygote
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/01/02 12:00:27」(JST)
[Wiki en表示]
The process of fertilization in the ovum of a mouse.
A pronucleus (plural: pronuclei) is the nucleus of a sperm or an egg cell during the process of fertilization, after the sperm enters the ovum, but before they fuse. Sperm and egg cells are haploid, meaning they carry half the number of chromosomes. The male and female pronuclei don't fuse, although their genetic material do. Instead, their membranes dissolve, leaving no barriers between the male and female chromosomes. Their chromosomes can then combine and become part of a single diploid nucleus in the resulting embryo, containing a full set of chromosomes.
The appearance of two pronuclei is the first sign of successful fertilization as observed during in vitro fertilisation, and is usually observed 18 hours after insemination or ICSI. The zygote is then termed a two-pronuclear zygote (2PN). Two-pronuclear zygotes transitioning through 1PN or 3PN states tend to develop into poorer-quality embryos than ones who remain 2PN throughout development,[1] and may be significant in embryo selection in IVF.
References
- ^ Reichman DE, Jackson KV, Racowsky C (May 2009). "Incidence and development of zygotes exhibiting abnormal pronuclear disposition after identification of two pronuclei at the fertilization check". Fertil. Steril. 94 (3): 965–970. doi:10.1016/j.fertnstert.2009.04.018. PMID 19476942.
External links
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Look up pronucleus in Wiktionary, the free dictionary. |
UpToDate Contents
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English Journal
- Sharpening the cutting edge: additional considerations for the UK debates on embryonic interventions for mitochondrial diseases.
- Haimes E1, Taylor K2.
- Life sciences, society and policy.Life Sci Soc Policy.2017 Dec;13(1):1. doi: 10.1186/s40504-016-0046-2. Epub 2017 Jan 13.
- In October 2015 the UK enacted legislation to permit the clinical use of two cutting edge germline-altering, IVF-based embryonic techniques: pronuclear transfer and maternal spindle transfer (PNT and MST). The aim is to use these techniques to prevent the maternal transmission of serious mitochondri
- PMID 28092013
- Impact of FMR1 Pre-Mutation Status on Blastocyst Development in Patients Undergoing Pre-Implantation Genetic Diagnosis.
- Hutchinson AP1, Pereira N, Lilienthal DP, Coveney S, Lekovich JP, Elias RT, Rosenwaks Z.
- Gynecologic and obstetric investigation.Gynecol Obstet Invest.2017 Feb 22. doi: 10.1159/000455849. [Epub ahead of print]
- BACKGROUND/AIMS: The study aimed to investigate the impact of fragile X mental retardation 1 (FMR1) pre-mutation status on blastocyst development in patients undergoing pre-implantation genetic diagnosis (PGD).METHODS: Case-control study of patients <40 years undergoing PGD at blastocyst stage fo
- PMID 28222427
- Quisinostat treatment improves histone acetylation and developmental competence of porcine somatic cell nuclear transfer embryos.
- Jin L1, Guo Q1, Zhu HY1, Xing XX1, Zhang GL1, Xuan MF1, Luo QR1, Luo ZB1, Wang JX1, Yin XJ1, Kang JD1.
- Molecular reproduction and development.Mol Reprod Dev.2017 Feb 22. doi: 10.1002/mrd.22787. [Epub ahead of print]
- Abnormal epigenetic modifications are considered a main contributing factor to low cloning efficiency. In the present study, we explored the effects of quisinostat, a novel histone deacetylase inhibitor, on blastocyst formation rate in porcine somatic-cell nuclear transfer (SCNT) embryos, on acetyla
- PMID 28224725
Japanese Journal
- Successful vitrification of pronuclear-stage pig embryos with a novel cryoprotective agent, carboxylated ε-poly-L-lysine
- 〈Original Papers〉ウサギ半数体ES細胞樹立に向けた雌性半数体胚の解析
- 近畿大学先端技術総合研究所紀要 = Memoirs of Institute of Advanced Technology, Kindai University (22), 13-23, 2017-03-31
- NAID 120006332225
- Efficient mutagenesis by CRISPR/Cas system during meiotic maturation of porcine oocytes
Related Links
- pro·nu·cle·us (prō-no o′klē-əs, -nyo o′-) n. pl. pro·nu·cle·i (-klē-ī′) The haploid nucleus of a sperm or egg before fusion of the nuclei in fertilization. pro·nu′cle·ar adj. pronuclear (ˌprəʊˈnjuːklɪə) adj (Government, Politics & Diplomacy) in ...
- pronuclearとは。意味や和訳。[形容詞] 原子力発電推進派の;核兵器支持派の.⇒NUCLEAR【発音】[語源]1963pronuclearist [名詞], [形容詞] - 80万項目以上収録、例文・コロケーションが豊富な無料英和和英辞典。
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前核
- 関
- anterior nuclei、pronuclear、pronuclei、pronucleus
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- 関
- anterior nuclei、anterior nucleus、pronuclear、pronuclei
[★]
前核
- 関
- anterior nuclei、anterior nucleus、pronuclear、pronucleus
[★]
前核
- 関
- anterior nucleus、pronuclear、pronuclei、pronucleus