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「synthetic antimalarial drug」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/02 13:34:10」(JST)

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  • Efficacy and safety of atovaquone-proguanil in treating imported malaria in Japan: The second report from the research group.
  • Kimura M, Koga M, Kikuchi T, Miura T, Maruyama H.SourceDepartment of Internal Medicine, Shin-Yamanote Hospital, Japan Anti-Tuberculosis Association, Tokyo, Japan.
  • Parasitology international.Parasitol Int.2012 Sep;61(3):466-9. Epub 2012 Mar 29.
  • Malaria remains an important health risk among travelers to tropical/subtropical regions. However, in Japan, only 2 antimalarials are licensed for clinical use - oral quinine and mefloquine. The Research Group on Chemotherapy of Tropical Diseases introduced atovaquone-proguanil in 1999, and reported
  • PMID 22484597
  • Extrahepatic exoerythrocytic forms of rodent malaria parasites at the site of inoculation: clearance after immunization, susceptibility to primaquine, and contribution to blood-stage infection.
  • Voza T, Miller JL, Kappe SH, Sinnis P.SourceDepartment of Medical Parasitology, New York University School of Medicine, New York, New York, USA.
  • Infection and immunity.Infect Immun.2012 Jun;80(6):2158-64. Epub 2012 Mar 19.
  • Plasmodium sporozoites are inoculated into the skin of the mammalian host as infected mosquitoes probe for blood. A proportion of the inoculum enters the bloodstream and goes to the liver, where the sporozoites invade hepatocytes and develop into the next life cycle stage, the exoerythrocytic, or li
  • PMID 22431651


  • Evidence of the formation of direct covalent adducts of primaquine, 2-tert-butylprimaquine (NP-96) and monohydroxy metabolite of NP-96 with glutathione and N-acetylcysteine
  • GARG Amit,PRASAD Bhagwat,TAKWANI Hardik,JAIN Meenakshi,JAIN Rahul,SINGH Saranjit
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 879(1), 1-7, 2011-01-01
  • NAID 10029025087
  • In vitro effect of current antimalarial drugs on the survival of paired Schistosoma mansoni adult worms and their egg production
  • MITSUI Yoshinori,AOKI Yoshiki
  • Tropical medicine and health 38(2), 69-73, 2010-06-01
  • NAID 10026955873


Primaquine is used alone or with another medication to treat malaria (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death) and to prevent the disease from coming back in ...
PharmGKB contains no dosing guidelines for this drug/small molecule. To report known genotype-based dosing guidelines, or if you are interested in developing ... PharmGKB gathers information regarding PGx on FDA drug labels ...


: Primaquine tablets (below) Primaquine  2D Image | Primaquine | C15H21N3OPRIMAQUINE DIPHOSPHATE SALTPrimaquine Tablets BP | NEW GPCPrimaquine and glucose-6-phosphate PRIMAQUINE-PHOSPHATE-1.png

拡張検索G6PD deficiency primaquine and

G6PD deficiency primaquine and」


Glucose-6-phosphate dehydrogenase deficiency