prepulse inhibition

出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/10/22 14:46:10」(JST)

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  • Frequency discrimination in rats exposed to noise as juveniles.
  • Šuta D1, Rybalko N2, Shen DW3, Popelář J2, Poon PW3, Syka J2.
  • Physiology & behavior.Physiol Behav.2015 May 15;144:60-5. doi: 10.1016/j.physbeh.2015.03.005. Epub 2015 Mar 4.
  • Sound exposure during the early postnatal period can significantly influence the function of the auditory system in rats during adulthood. In the present study, rat pups (strain Long-Evans) were exposed to broad-band noise at 125dB SPL for 8, 12 or 25min on postnatal day 14 and then at the age of 3-
  • PMID 25747769
  • Sex-specific alterations in behavioral and cognitive functions in a "three hit" animal model of schizophrenia.
  • Kekesi G1, Petrovszki Z2, Benedek G3, Horvath G4.
  • Behavioural brain research.Behav Brain Res.2015 May 1;284:85-93. doi: 10.1016/j.bbr.2015.02.015. Epub 2015 Feb 16.
  • Whereas schizophrenia affects both human sexes, there are known sex-dependent disparities. We developed a chronic animal model that shows some schizophrenia-related deficits in rats by applying selective breeding after subchronic ketamine administration connected with postweaning social isolation (c
  • PMID 25698594
  • Constant light uncovers behavioral effects of a mutation in the schizophrenia risk gene Dtnbp1 in mice.
  • Bhardwaj SK1, Stojkovic K1, Kiessling S1, Srivastava LK2, Cermakian N3.
  • Behavioural brain research.Behav Brain Res.2015 May 1;284:58-68. doi: 10.1016/j.bbr.2015.01.048. Epub 2015 Feb 9.
  • Various psychiatric disorders, including schizophrenia, are comorbid with sleep and circadian rhythm disruptions. To understand the links between circadian rhythms and schizophrenia, we analyzed wheel-running behavior of Sandy (Sdy) mice, which have a loss-of-function mutation in the schizophrenia r
  • PMID 25677649


  • P8-02 Definition of the Prepulse Inhibition related tegmentum containing GABAergic projection neurons in the rat
  • 日本組織細胞化学会総会プログラムおよび抄録集 (56), 77, 2015-10-03
  • NAID 110009996369
  • 自閉症スペクトラム障害児における聴覚性驚愕反射の特性とエンドフェノタイプ候補可能性の検討 (特集 自閉症スペクトラム障害の早期マーカー)
  • 日本生物学的精神医学会誌 = Japanese journal of biological psychiatry 26(2), 103-108, 2015-06
  • NAID 40020552449
  • Effects of sodium benzoate on pre-pulse inhibition deficits and hyperlocomotion in mice after administration of phencyclidine


Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease. Clin Psychopharmacol Neurosci: 2011, 9(3);102-10 [PubMed:23429840] [] [DOI] ↑ 2.0 2.1 2.2 Neal R Swerdlow, Martin ...
prepulse inhibition(PPI).先に弱い刺激を加えることで,突然与えられた強い刺激に対する驚愕反応が抑制される現象のこと.情報処理における障害の指標と考えられ,PPIの減少は統合失調症をはじめとするヒト精神疾患のみならず,動物 ...








prepulse inhibition, PPI



  • n.
  • 1.抑止、抑制、阻止、禁止
  • 2.抑止(阻止)するもの
  • 3.(心理学)(衝動などの)抑制
  • 4.(化)(化学反応の)抑制
  • 5.(生物)(酵素の働きなどの)抑制、阻害

WordNet   license wordnet

「(physiology) the process whereby nerves can retard or prevent the functioning of an organ or part; "the inhibition of the heart by the vagus nerve"」

WordNet   license wordnet

「(psychology) the conscious exclusion of unacceptable thoughts or desires」

WordNet   license wordnet

「the quality of being inhibited」

PrepTutorEJDIC   license prepejdic

「禁止; 抑制; (心理学で)抑制; (化学で)(反応の)阻害, 抑制」