potassium channel agonist

出典: meddic



  • Pharmacological Evidence Showing Significant Roles for Potassium Channels and CYP Epoxygenase Metabolites in the Relaxant Effects of Docosahexaenoic Acid on the Rat Aorta Contracted with U46619
  • Sato Kyosuke,Chino Daisuke,Nishioka Nanako [他],Kanai Keisuke,Aoki Mika,Obara Keisuke,Miyauchi Seiji,Tanaka Yoshio
  • Biological and Pharmaceutical Bulletin 37(3), 394-403, 2014
  • … In endothelium-denuded rat thoracic aorta, DHA (10−5 <span style="font-variant: small-caps;">M</span>) almost completely relaxed U46619 (a thromboxane A2 (TP) receptor agonist)-contracted muscle without substantially affecting noradrenaline (NA)-induced contraction. … tetraethylammonium (TEA) which non-selectively inhibits K+ channel activity. …
  • NAID 130003382129
  • Ionic and Cellular Mechanisms Underlying the Development of Acquired Brugada Syndrome in Patients Treated with Antidepressants
  • Minoura Yoshino,M. Di Diego Jose,Barajas-Martinez Hector,C. Zygmunt Andrew,Hu Dan,Sicouri Serge,Antzelevitch Charles
  • Journal of Arrhythmia 27(Supplement), CP2_01-CP2_01, 2011
  • … In the presence of NS5806 (8 µM), a transient outward potassium channel current (I<SUB>to</SUB>) agonist, a therapeutic concentration of amitriptyline (0.2 µM) accentuated the epicardial AP notch leading to ST-segment elevation of the ECG. …
  • NAID 130002130143







  • n.
  • 川床、川底。水路、河道
  • 海峡
  • 水管、導管
  • 経路、ルート。道筋、方向
ion channelionic channel

WordNet   license wordnet

「direct the flow of; "channel information towards a broad audience"」
canalize, canalise

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「a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels"」
television channel, TV channel

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「a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"」

WordNet   license wordnet

「(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms"」
communication channel, line

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「a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company"」
transmission channel

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「a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"」

PrepTutorEJDIC   license prepejdic

「〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す」


  [★] カリウム

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「a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite」
K, atomic number 19

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  [★] 作動薬

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「(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction」

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「a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"」

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「someone involved in a contest or battle (as in an agon)」


  [★] チャネル

WordNet   license wordnet

「official routes of communication; "you have to go through channels"」