光線過敏性反応、光過敏性反応

WordNet

(mechanics) the equal and opposite force that is produced when any force is applied to a body; "every action has an equal and opposite reaction"
a response that reveals a persons feelings or attitude; "he was pleased by the audiences reaction to his performance"; "John feared his mothers reaction when she saw the broken lamp"
a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age" (同)response
doing something in opposition to another way of doing it that you dont like; "his style of painting was a reaction against cubism"
an idea evoked by some experience; "his reaction to the news was to start planning what to do"
extreme conservatism in political or social matters; "the forces of reaction carried the election"
sensitivity to the action of radiant energy (同)radiosensitivity

PrepTutorEJDIC

{名}(…に対する)『反応』《+『to』+『名』》 / 〈U〉(…に対する)(政治的・社会的な)『反動』,逆コース《+『against』+『名』》 / 〈U〉〈C〉化学反応,化学変化 / 〈U〉〈C〉(物理学で)反作用

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/05/01 14:32:53」(JST)

wiki en

Photodermatitis, sometimes referred to as "sun poisoning" or photoallergy is a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous.

Causes

Many medications and conditions can cause sun sensitivity, including:

Psoralens, coal tars, photo-active dyes (eosin, acridine orange)
Musk ambrette, methylcoumarin, lemon oil (may be present in fragrances)
PABA (found in sunscreens)
Salicylanilide (found in industrial cleaners)
St John's Wort, used to treat clinical depression
Hexachlorophene (found in some ℞ antibacterial soaps)
Contact with sap from Giant Hogweed. Common Rue (Ruta graveolins) is another phototoxic plant commonly found in gardens.
Tetracycline antibiotics
NSAIDs.
Fluoroquinolone antibiotic: Sparfloxacin in 2% of cases.
Amiodarone, used to treat atrial fibrillation
Pellagra

Photodermatitis can also be caused by plants. This is called phytophotodermatitis.

Symptoms

May result in swelling, a burning sensation, a red itchy rash sometimes resembling small blisters, and peeling of the skin. Nausea may also occur. There may also be blotches of large to small areas where the itching may persist for long periods of time. In these areas an unsightly orange to brown tint may form, usually near or on the face.

Prevention

Prevention includes avoiding exposure to the sun and wearing sun block on the affected area.

Cover up: wear long sleeves, slacks, and a wide-brimmed hat whenever harsh exposure is probable
Avoid chemicals that may trigger a reaction
Wear sunscreen^[1]^[2] at least factor 30 with a high UVA protection level
Wear gloves and/or remain indoors after handling fruits or plants which increase sensitivity to light

References

^ Archived AAD - The Sun and Your Skin, "Allergic Reactions" section
^ AAD - Sunscreens

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UpToDate Contents

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1. 光線過敏症（光線皮膚症）：臨床症状、診断、および治療 photosensitivity disorders photodermatoses clinical manifestations diagnosis and treatment
2. 皮膚光線過敏症の概要：光生物学、患者評価、および光保護 overview of cutaneous photosensitivity photobiology patient evaluation and photoprotection
3. 分子標的剤およびその他の生物製剤を用いた癌治療による皮膚合併症 cutaneous complications of molecularly targeted therapy and other biologic agents used for cancer therapy
4. 顔面紅斑が認められる患者に対するアプローチ approach to the patient with facial erythema
5. 従来の癌の化学療法による皮膚合併症 cutaneous complications of conventional chemotherapy agents

English Journal

Photochromic Properties of [2.2]Paracyclophane-Bridged Imidazole Dimer with Increased Photosensitivity by Introducing Pyrenyl Moiety.

Yamashita H, Abe J.AbstractThe photochromic [2.2]paracyclophane-bridged imidazole dimers show instantaneous coloration upon exposure to UV light and rapid fading in the dark. A new [2.2]paracyclophane-bridged imidazole dimer, pseudogem-PPI-DPI[2.2]PC, with high photosensitivity to UVA radiation was developed. In order to enhance the photosensitivity, we introduced pyrenyl moieties to the [2.2]paracyclophane-bridged imidazole dimer. The localized Π-Π*?transition of pyrenyl moieties appears in the UVA radiation region by introducing a pyrenyl moietiy on the 4-position of the imidazole rings. The expansion of Π-electron system also affects the absorption spectrum of the colored species. The broad absorption band of the colored species covers whole range of visible light region and its absorbance is approximately equal throughout the visible light region. Thus, pseudogem-PPI-DPI[2.2]PC shows the photochromic reaction coloring black upon light irradiation and successive fast thermal bleaching following the monoexponential kinetics with a time constant of 12 ms at room temperature.
The journal of physical chemistry. A.J Phys Chem A.2011 Oct 8. [Epub ahead of print]
The photochromic [2.2]paracyclophane-bridged imidazole dimers show instantaneous coloration upon exposure to UV light and rapid fading in the dark. A new [2.2]paracyclophane-bridged imidazole dimer, pseudogem-PPI-DPI[2.2]PC, with high photosensitivity to UVA radiation was develope
PMID 21980950

Ultraviolet recall dermatitis reaction with sorafenib.

Magne N, Chargari C, Auberdiac P, Moncharmont C, Merrouche Y, Spano JP.SourceDepartment of Radiotherapy, Institut de Cancerologie de la Loire, 108 bis, avenue Albert Raimond, BP 60008, 42271 Saint Priest en Jarez, France. nicolas.magne@icloire.fr
Investigational new drugs.Invest New Drugs.2011 Oct;29(5):1111-3. Epub 2010 Jun 22.
PURPOSE: Recall dermatitis is a rare and poorly understood drug-related event. Activated by exposure to sunlight or Ultraviolet (UV), drug-related phototoxic reactions have been reported with conventional chemotherapy agents or antibiotics.METHODS: Here, we report the first case of acute dermatologi
PMID 20567994

Japanese Journal

ポリマー/現像液間の反応を鍵とした新規画像形成法-反応現像画像形成-によるエンジニアリングプラスチックの感光化

大山俊幸
有機合成化学協会誌 68(8), 802-813, 2010-08-01
… Here, we report a novel design for preparation of photosensitive polyimides, reaction development patterning(RDP). … RDP utilizes nucleophilic acyl substitution reaction of nucleophiles in developer with imide groups in polyimides as the key reaction of pattern formation, and therefore, no introduction of specific functional groups into polyimide framework is needed. …
NAID 10026870120

耳鼻咽喉科・頭頸部外科領域に対する光線力学的治療

吉田知之
耳鼻咽喉科臨床 102(11), 889-899, 2009-11-01
… This treatment is a first-line treatment for carcinoma based on a photochemical reaction in which a photosensitizer is excited by laser irradiation, causing selective death of tumor tissue. … No adverse experience/event was seen in terms of critical photosensitivity and blood biochemical toxicity. …
NAID 10025527272

Related Pictures

★リンクテーブル★

リンク元	「光過敏性反応」「光線過敏性反応」
関連記事	「reaction」「photosensitivity」

「光過敏性反応」

Photodermatitis
	Classification and external resources
	; An image of a patch of sun poisoning on the left forearm
ICD-10	L57.8
ICD-9	692.79
DiseasesDB	24609
MeSH	D010787