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  • Using glow stick chemistry for biological imaging.
  • Tseng JC1, Bailey D, Tupper T, Kung AL.
  • Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.Mol Imaging Biol.2014 Aug;16(4):478-87. doi: 10.1007/s11307-014-0721-8.
  • PURPOSE: This study describes an imaging strategy based on glow stick chemistry to non-invasively image oxidative stress and reactive oxygen species (ROS) production in living animals.PROCEDURES: Upon stimulation, phagocytes produce toxic levels of ROS to kill engulfed microorganisms. The mitochondr
  • PMID 24510470
  • Nanoparticle uptake by airway phagocytes after fungal spore challenge in murine allergic asthma and chronic bronchitis.
  • Geiser M, Wigge C, Conrad ML, Eigeldinger-Berthou S, Künzi L, Garn H, Renz H, Mall MA.
  • BMC pulmonary medicine.BMC Pulm Med.2014 Jul 16;14(1):116. [Epub ahead of print]
  • BACKGROUND: In healthy lungs, deposited micrometer-sized particles are efficiently phagocytosed by macrophages present on airway surfaces; however, uptake of nanoparticles (NP) by macrophages appears less effective and is largely unstudied in lung disease. Using mouse models of allergic asthma and c
  • PMID 25027175
  • Early Induction of IL-10 Limits Antigen-specific CD4+ T Cell Expansion, Function and Secondary Recall Responses during Persistent Phagosomal Infection.
  • Singh AK1, Thirumalapura NR2.
  • Infection and immunity.Infect Immun.2014 Jul 14. pii: IAI.02101-14. [Epub ahead of print]
  • Diverse pathogens have evolved to survive and replicate in the endosomes or phagosomes of the host cells and establish persistent infection. Ehrlichia are Gram-negative, intracellular bacteria that are transmitted by ticks. Ehrlichia reside in the endosomes of the host phagocytic or endothelial cell
  • PMID 25024370


  • Amyloid β oligomers induce interleukin-1β production in primary microglia in a cathepsin B- and reactive oxygen species-dependent manner.
  • Taneo Jun,Adachi Takumi,Yoshida Aiko,Takayasu Kunio,Takahara Kazuhiko,Inaba Kayo
  • Biochemical and biophysical research communications 458(3), 561-567, 2015-03-13
  • … Moreover, Aβ oligomers induced endo/phagolysosome rupture, which released cathepsin B into the cytoplasm. …
  • NAID 120005575184
  • 結核菌ファゴソームの分子解剖
  • 瀬戸 真太郎,永田 年,堀井 俊伸 [他],小出 幸夫
  • 日本細菌学雑誌 69(3), 513-525, 2014
  • 結核菌は細胞内寄生性細菌であり, 貪食されたマクロファージ内で増殖することができる。結核菌の細胞内増殖能はファゴリソソーム形成を阻害することによって獲得している。一方で, 感染結核菌の排除には, 細胞質タンパク質分解機構であるオートファジー誘導が関与しているといわれている。これまで, 結核菌による細胞内増殖機構を解明するため, 結核菌感染マクロファージにおける小胞輸送について数多くの報告がなされて …
  • NAID 130004688030
  • 結核菌の細胞内寄生メカニズム (特集 結核とその類縁疾患--基礎と臨床の最新知見) -- (結核感染成立要因の基礎研究)
  • 瀬戸 真太郎,辻村 邦夫,小出 幸夫
  • 日本臨床 69(8), 1373-1377, 2011-08
  • NAID 40018932263


Looking for online definition of phagolysosome in the Medical Dictionary? phagolysosome explanation free. What is phagolysosome? Meaning of phagolysosome medical term. What does phagolysosome mean? http://medical ...
phagolysosome phag·o·ly·so·some (fāg'ə-lī'sə-sōm') n. A cellular body that is formed by the union of a phagosome or an ingested particle with a lysosome that contains hydrolytic enzymes.