English Journal
- [Clinical evaluation of imipenem/cilastatin sodium in children].
- Meguro H, Arimasu O, Kobayashi M, Shiraishi H, Fujii R, Izumi K.AbstractImipenem/cilastatin sodium (MK-0787/MK-0791) was evaluated for its safety, efficacy and pharmacokinetics in children. Thirty cases of bacterial infections were treated with MK-0787/MK-0791 at a daily dose of 40 to 222 mg/kg for 2.25 to 13 days. Clinical cure rate was 93% and bacteriological efficacy rate was 88%. Treated diseases included severe tonsillitis due to mixed anaerobic infections, pneumonia, sepsis, brain abscess and soft tissue infections. Two cases, one with periosteomyelitis due to methicillin-resistant S. aureus and the other with pulmonary abscess due to Haemophilus influenzae (other than type b), failed to respond to the MK-0787/MK-0791 therapy. The serum half-life of MK-0787 was 0.892 hour in children with normal renal functions. An episode of convulsions in a case of sepsis with bacterial croup and brain edema was considered to be associated with the MK-0787/MK-0791 therapy. From the present study, MK-0787/MK-0791 appears a safe and effective antibiotic when used in children with a variety of bacterial infections.
- The Japanese journal of antibiotics.Jpn J Antibiot.1986 Jul;39(7):1715-32.
- Imipenem/cilastatin sodium (MK-0787/MK-0791) was evaluated for its safety, efficacy and pharmacokinetics in children. Thirty cases of bacterial infections were treated with MK-0787/MK-0791 at a daily dose of 40 to 222 mg/kg for 2.25 to 13 days. Clinical cure rate was 93% and bacteriological efficacy
- PMID 3464775
- [Therapeutic course of infantile periosteomyelitis and the present status of resistance of pyogenic bacteria].
- Yanase T, Sugiyama Y, Yamazaki M.
- Seikeigeka. Orthopedic surgery.Seikei Geka.1966 Jan;17(1):47-52.
- PMID 6006590
Japanese Journal
- 先天梅毒による多発性骨髄骨膜炎の一例
- 北沢 俊郎,KITAZAWA Toshiro
- 東京女子医科大学雑誌 27(12), 774-778, 1957-12
- NAID 120002362449
Related Links
- Acronyms. Idioms. Encyclopedia. Wikipedia encyclopedia ? periosteomyelitis. 0.01 sec. periosteomyelitis /peri·os·teo·my·eli·tis/ (-os″te-o-mi″ĕ-li´tis) inflammation of the entire bone, including periosteum and marrow. per·i·os·te·o· my·e·li·tis (p r ...
- 6 Nov 2012 ... Periosteomyelitis information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.
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★リンクテーブル★
| リンク元 | 「骨髄炎」「骨膜骨髄炎」 |
「骨髄炎」
- 英
- osteomyelitis
- 同
- 骨膜骨髄炎 periosteomyelitis
- 関
- [[]]
分類
- 急性化膿性骨髄炎：成長期における長管骨骨幹端部の血行系の解剖学的特異性に起因する血行性感染で、小児、特に男児に多い。大腿骨、脛骨、上腕骨の順に多発する。黄色ブドウ球菌。骨髄内で膿瘍を形成、さらに骨膜下に波及して骨膜下膿瘍を形成する。骨壊死をきたした壊死骨は腐骨と呼ばれる。その周囲は膿や炎症性肉芽で取り囲まれ汚溝と呼ばれる。その外側を反応性に骨形成が起こり腐骨と汚溝を取り囲む。これが骨柩となる。
- 慢性骨髄炎
- ブローディ膿瘍 Brodie膿瘍：急性症状を欠く慢性骨髄炎。長管骨骨幹端部。黄色ブドウ球菌。小児や青年期に好発。辺縁の骨硬化を伴う円形ないし楕円形の骨透明巣
- ガレー硬化性骨髄炎 Garré硬化性骨髄炎：急性期を欠く慢性骨髄炎。膿瘍や腐骨の形成を欠きXP上骨硬化像を認める。皮質骨の骨肥厚により骨が紡錘状に膨隆する。下顎骨に多い。
- 化膿性脊椎炎
「骨膜骨髄炎」
- 英
- periosteomyelitis
- 関
- 骨髄炎、骨膜炎