WordNet

of or involving the pancreas; "pancreatic cancer"
absence of gastric juices (partial or complete) (同)achylia_gastrica

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膵臓の

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1. 膵臓ステント留置術およびその合併症の概要 overview of pancreatic stenting and its complications
2. 膵外分泌癌の治療における外科手術の概要 overview of surgery in the treatment of exocrine pancreatic cancer and prognosis
3. 膵嚢胞の分類 classification of pancreatic cysts
4. 膵嚢胞性腫瘍 pancreatic cystic neoplasms
5. 膵外分泌癌の臨床症状、診断、および病期分類 clinical manifestations diagnosis and staging of exocrine pancreatic cancer

English Journal

Histogenesis and Natural History of Gut Neuroendocrine Tumors: Present Status.

Solcia E1, Vanoli A.Author information 1Fondazione IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy, solciae@smatteo.pv.it.AbstractImportant progress has been made during the last decade in the histopathologic characterization and overall prognostic evaluation of gut neuroendocrine tumors. However, some issues like tumor histogenesis, typing, functional characterization, and preferred site of origin deserve further clarification. This is a survey of the present status of the matter outlining some of the open points. In particular, careful comparison of normal gut endocrine cell types with related endocrine tumors so far identified shows an unexplained lack of neoplasms involving upper small intestine cells like secretin, cholecystokinin, motilin, and GIP cells, as well as the equally unexplained concentration of serotonin EC cell tumors in the ileum and appendix or of somatostatin cell tumors in the duodenal papillary region, despite their wide distribution in the normal gut, not to mention gastrinomas arising in the pancreas, normally devoid of gastrin cells. Special functional (e.g., achlorhydria-driven hypergastrinemia) or pathologic (as chronic inflammation) conditions may locally influence the proliferative and differentiation state of the endocrine cells thus promoting tumor growth. Tumor histologic structure, differentiation level, and proliferative index as well as gastrointestinal wall barriers to tumor diffusion may account for most prognostic parameters, with considerable changes, however, according to the tumor type and site. Thus, further work is needed to develop tumor- and site-adjusted prognostic parameters.
Endocrine pathology.Endocr Pathol.2014 Apr 4. [Epub ahead of print]
Important progress has been made during the last decade in the histopathologic characterization and overall prognostic evaluation of gut neuroendocrine tumors. However, some issues like tumor histogenesis, typing, functional characterization, and preferred site of origin deserve further clarificatio
PMID 24699926

Hypochlorhydria and achlorhydria are associated with false-positive secretin stimulation testing for Zollinger-Ellison syndrome.

Shah P1, Singh MH, Yang YX, Metz DC.Author information 1Division of Gastroenterology and Nutrition, Memorial-Sloan Kettering Cancer Center, New York, NY, USA.AbstractOBJECTIVES: Secretin stimulation testing (SST) is used to evaluate patients with hypergastrinemia in the diagnosis of Zollinger-Ellison syndrome. Case series have documented false-positive SST in patients with achlorhydria. This study reviews our experience with SST in hypochlorhydric and achlorhydric patients.
Pancreas.Pancreas.2013 Aug;42(6):932-6. doi: 10.1097/MPA.0b013e3182847b2e.
OBJECTIVES: Secretin stimulation testing (SST) is used to evaluate patients with hypergastrinemia in the diagnosis of Zollinger-Ellison syndrome. Case series have documented false-positive SST in patients with achlorhydria. This study reviews our experience with SST in hypochlorhydric and achlorhydr
PMID 23851430