orotidine-5'-phosphate decarboxylase

出典: meddic


orotidine-5'-monophosphate decarboxylase

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/11/08 23:21:10」(JST)

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  • Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks.
  • Gerlt JA1, Bouvier JT2, Davidson DB3, Imker HJ3, Sadkhin B3, Slater DR3, Whalen KL3.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2015 Aug;1854(8):1019-37. doi: 10.1016/j.bbapap.2015.04.015. Epub 2015 Apr 18.
  • The Enzyme Function Initiative, an NIH/NIGMS-supported Large-Scale Collaborative Project (EFI; U54GM093342; http://enzymefunction.org/), is focused on devising and disseminating bioinformatics and computational tools as well as experimental strategies for the prediction and assignment of functions (
  • PMID 25900361
  • Biotransformation of acetophenone and its halogen derivatives by Yarrowia lipolytica strains.
  • Janeczko T1, Bąkowski W1, Walczak E2, Robak M3, Dmochowska-Gładysz J4, Kostrzewa-Susłow E1.
  • Annals of microbiology.Ann Microbiol.2015;65(2):1097-1107. Epub 2014 Aug 22.
  • The ability of 16 strains of Yarrowia lipolytica to biotransform acetophenone and its derivatives has been studied. Thirteen of these strains were derived from a wild-type strain Y. lipolytica A-101; six had the invertase gene (SUC2) from Saccharomyces cerevisiae integrated into their genome, as wel
  • PMID 26005401
  • Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution.
  • Desai BJ1, Goto Y2, Cembran A3, Fedorov AA4, Almo SC4, Gao J5, Suga H2, Gerlt JA6.
  • Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Oct 21;111(42):15066-71. doi: 10.1073/pnas.1411772111. Epub 2014 Oct 1.
  • Hydrogen bonds between backbone amide groups of enzymes and their substrates are often observed, but their importance in substrate binding and/or catalysis is not easy to investigate experimentally. We describe the generation and kinetic characterization of a backbone amide to ester substitution in
  • PMID 25275007


  • A Ternary Conjugation System for the Construction of DNA Libraries for Geobacillus kaustophilus HTA426
  • SUZUKI Hirokazu,WADA Keisuke,FURUKAWA Megumi [他]
  • Bioscience, Biotechnology, and Biochemistry 77(11), 2316-2318, 2013-11
  • NAID 40019898399
  • Isolation of Mutants of the Nitrogen-Fixing Actinomycete Frankia
  • Kakoi Kentaro,Yamaura Masatoshi,Kamiharai Toshihito,Tamari Daiki,Abe Mikiko,Uchiumi Toshiki,Kucho Ken-Ichi
  • Microbes and Environments, 2013
  • … Firstly, we isolated uracil auxotrophs as gain-of-function mutants resistant to 5-fluoroorotic acid (5-FOA). … We obtained seven 5-FOA resistant mutants, all of which required uracil for growth. … Five strains carried a frame shift mutation in orotidine-5'-phosphate decarboxylase gene and two carried an amino acid substitution in the orotate phosphoribosyltransferase gene. …
  • NAID 130003382027
  • A Ternary Conjugation System for the Construction of DNA Libraries for Geobacillus kaustophilus HTA426
  • SUZUKI Hirokazu,WADA Keisuke,FURUKAWA Megumi,DOI Katsumi,OHSHIMA Toshihisa
  • Bioscience, Biotechnology, and Biochemistry, 2013
  • … kaustophilus and to identify the genes for orotidine-5'-phosphate decarboxylase by in vivo functional screening. …
  • NAID 130003381932


Orotidine 5'-phosphate decarboxylase (OMPdecase) (EC: [PMID: 2835631, PMID: 1730672] catalyzes the last step in the de novo biosynthesis of pyrimidines, the decarboxylation of OMP into UMP. In higher eukaryotes ...
cytosol, orotidine-5'-phosphate decarboxylase activity, 'de novo' pyrimidine nucleobase biosynthetic process, UMP biosynthetic process ... <p>Describes the metabolic pathway(s) associated with a protein.</p><p><a href='../manual ...






orotidine-5'-monophosphate decarboxylase、orotidine-5'-phosphate decarboxylase



orotidine-5'-phosphate decarboxylase



  • n.
inorganic phosphateorthophosphateorthophosphoric acidphosphophosphoesterphosphoricphosphoric acidphosphoric acid esterphosphorus

WordNet   license wordnet

「a salt of phosphoric acid」
orthophosphate, inorganic phosphate

WordNet   license wordnet

「carbonated drink with fruit syrup and a little phosphoric acid」

PrepTutorEJDIC   license prepejdic

「〈U〉リン酸塩 / 《複数形で》リン酸肥料」





WordNet   license wordnet

「any of the enzymes that hydrolize the carboxyl group」